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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell fate specification
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Accession:GO:0009996 term browser browse the term
Definition:Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:exact_synonym: down regulation of cell fate specification;   downregulation of cell fate specification;   suppression of cell fate
 narrow_synonym: inhibition of cell fate specification


show annotations for term's descendants       view all columns           Sort by:
 
negative regulation of cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fzd7 frizzled class receptor 7 JBrowse link 9 66,305,731 66,308,550 RGD:1624291
negative regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    developmental process 6637
      cellular developmental process 4414
        cell fate specification 104
          negative regulation of cell fate specification 6
            negative regulation of atrichoblast fate specification 0
            negative regulation of auditory receptor cell fate specification 0
            negative regulation of cardiac cell fate specification + 1
            negative regulation of compound eye cone cell fate specification 0
            negative regulation of ectodermal cell fate specification 1
            negative regulation of endodermal cell fate specification 1
            negative regulation of fusion cell fate specification 0
            negative regulation of mesodermal cell fate specification + 3
            negative regulation of neural crest cell fate specification 0
            negative regulation of retinal cone cell fate specification 0
            negative regulation of terminal cell fate specification, open tracheal system 0
            negative regulation of trichoblast fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 19332
    biological regulation 13335
      regulation of biological process 12650
        negative regulation of biological process 5553
          negative regulation of developmental process 1096
            negative regulation of cell differentiation 811
              negative regulation of cell fate commitment 16
                negative regulation of cell fate specification 6
                  negative regulation of atrichoblast fate specification 0
                  negative regulation of auditory receptor cell fate specification 0
                  negative regulation of cardiac cell fate specification + 1
                  negative regulation of compound eye cone cell fate specification 0
                  negative regulation of ectodermal cell fate specification 1
                  negative regulation of endodermal cell fate specification 1
                  negative regulation of fusion cell fate specification 0
                  negative regulation of mesodermal cell fate specification + 3
                  negative regulation of neural crest cell fate specification 0
                  negative regulation of retinal cone cell fate specification 0
                  negative regulation of terminal cell fate specification, open tracheal system 0
                  negative regulation of trichoblast fate specification 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.