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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cell fate specification
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Accession:GO:0009996 term browser browse the term
Definition:Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
Synonyms:exact_synonym: down regulation of cell fate specification;   downregulation of cell fate specification;   suppression of cell fate
 narrow_synonym: inhibition of cell fate specification


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negative regulation of cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor ISO MGI:2449921 (MGI:3606816|PMID:16230531) RGD PMID:16230531 MGI:3606816 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd7 frizzled class receptor 7 ISO (PMID:18681827) RGD PMID:18681827 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      cellular developmental process 4457
        cell fate specification 100
          negative regulation of cell fate specification 6
            negative regulation of atrichoblast fate specification 0
            negative regulation of auditory receptor cell fate specification 0
            negative regulation of cardiac cell fate specification + 1
            negative regulation of compound eye cone cell fate specification 0
            negative regulation of ectodermal cell fate specification 1
            negative regulation of endodermal cell fate specification 1
            negative regulation of fusion cell fate specification 0
            negative regulation of mesodermal cell fate specification + 3
            negative regulation of neural crest cell fate specification 0
            negative regulation of retinal cone cell fate specification 0
            negative regulation of terminal cell fate specification, open tracheal system 0
            negative regulation of trichoblast fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        negative regulation of biological process 5689
          negative regulation of developmental process 1015
            negative regulation of cell differentiation 735
              negative regulation of cell fate commitment 16
                negative regulation of cell fate specification 6
                  negative regulation of atrichoblast fate specification 0
                  negative regulation of auditory receptor cell fate specification 0
                  negative regulation of cardiac cell fate specification + 1
                  negative regulation of compound eye cone cell fate specification 0
                  negative regulation of ectodermal cell fate specification 1
                  negative regulation of endodermal cell fate specification 1
                  negative regulation of fusion cell fate specification 0
                  negative regulation of mesodermal cell fate specification + 3
                  negative regulation of neural crest cell fate specification 0
                  negative regulation of retinal cone cell fate specification 0
                  negative regulation of terminal cell fate specification, open tracheal system 0
                  negative regulation of trichoblast fate specification 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.