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ONTOLOGY REPORT - ANNOTATIONS


Term:cardioblast differentiation
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Accession:GO:0010002 term browser browse the term
Definition:The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
Synonyms:exact_synonym: cardiac precursor cell differentiation;   cardioblast cell differentiation
 related_synonym: cardiomyocyte generation


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cardioblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
cardiac muscle cell myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
RGD:1600115
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1624291
RGD:1600115
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prickle1 prickle planar cell polarity protein 1 JBrowse link 7 134,702,964 134,799,437 RGD:1600115
RGD:1624291
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
positive regulation of cardioblast differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1600115
RGD:1624291
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1624291
RGD:1600115
G Nkx2-5 NK2 homeobox 5 JBrowse link 10 16,635,989 16,638,758 RGD:1624291
RGD:1600115
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:1600115
RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Srf serum response factor JBrowse link 9 16,737,637 16,747,226 RGD:1624291
G Tbxt T-box transcription factor T JBrowse link 1 52,887,067 52,900,691 RGD:1624291
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Tbx2 T-box transcription factor 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17241
      cellular developmental process 4415
        cell differentiation 4195
          cardiocyte differentiation 183
            cardioblast differentiation 19
              cardiac muscle cell myoblast differentiation + 11
              cardioblast cell fate commitment + 1
              endocardial precursor cell differentiation + 0
              negative regulation of cardioblast differentiation + 2
              positive regulation of cardioblast differentiation + 6
              regulation of cardioblast differentiation + 8
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            circulatory system development 1201
              heart development 682
                cardiocyte differentiation 183
                  cardioblast differentiation 19
                    cardiac muscle cell myoblast differentiation + 11
                    cardioblast cell fate commitment + 1
                    endocardial precursor cell differentiation + 0
                    negative regulation of cardioblast differentiation + 2
                    positive regulation of cardioblast differentiation + 6
                    regulation of cardioblast differentiation + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.