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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of hydrogen peroxide metabolic process
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Accession:GO:0010310 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
Synonyms:exact_synonym: regulation of hydrogen peroxide metabolism


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regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insr insulin receptor ISO in cerebellar granule neurons RGD PMID:17919343 RGD:2290474 NCBI chrNW_004936588:4,345,306...4,453,380 JBrowse link
G Noxa1 NADPH oxidase activator 1 ISO (PMID:16636067) BHF-UCL PMID:16636067 NCBI chrNW_004936669:632,864...641,257 JBrowse link
G Pink1 PTEN induced kinase 1 ISO (MGI:MGI:5558956|PMID:24553947) ParkinsonsUK-UCL PMID:24553947 MGI:MGI:5558956 NCBI chrNW_004936474:6,574,471...6,589,478 JBrowse link
G Prdx2 peroxiredoxin 2 ISO (MGI:MGI:3758374|PMID:17325201) MGI PMID:17325201 MGI:MGI:3758374 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctns cystinosin, lysosomal cystine transporter ISO RGD PMID:26482480 RGD:12910938 NCBI chrNW_004936677:342,964...360,890 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like ISO (PMID:22306510) BHF-UCL PMID:22306510 NCBI chrNW_004936501:3,017,071...3,028,294 JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RGD PMID:23590160 RGD:8694322 NCBI chrNW_004936490:17,119,189...17,178,402 JBrowse link
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101976500 haptoglobin ISO (PMID:19740759) BHF-UCL PMID:19740759 NCBI chrNW_004936475:21,841,054...21,845,821 JBrowse link
G Mt3 metallothionein 3 ISO RGD PMID:12058024 RGD:625483 NCBI chrNW_004936475:8,864,512...8,866,516 JBrowse link
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:11991626 RGD:10003093 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duoxa1 dual oxidase maturation factor 1 ISO (PMID:22814254) UniProt PMID:22814254 NCBI chrNW_004936471:7,836,790...7,846,437 JBrowse link
G Duoxa2 dual oxidase maturation factor 2 ISO (PMID:16651268)
(PMID:22814254)
UniProt PMID:16651268, PMID:22814254 NCBI chrNW_004936471:7,832,234...7,835,488 JBrowse link
G Mfn2 mitofusin 2 ISO RGD PMID:27997345 RGD:12910740 NCBI chrNW_004936474:767,754...795,258 JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chrNW_004936489:11,178,338...11,191,601 JBrowse link
G Znf205 zinc finger protein 205 ISO (PMID:22306510) BHF-UCL PMID:22306510 NCBI chrNW_004936694:1,072,633...1,084,923 JBrowse link
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nnt nicotinamide nucleotide transhydrogenase ISO RGD PMID:24722990 RGD:13513981 NCBI chrNW_004936480:18,599,037...18,692,097 JBrowse link
G Snca synuclein alpha ISO (PMID:23507046) ParkinsonsUK-UCL PMID:23507046 NCBI chrNW_004936685:2,077,017...2,175,298 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    metabolic process 7653
      cellular metabolic process 7051
        reactive oxygen species metabolic process 268
          hydrogen peroxide metabolic process 41
            regulation of hydrogen peroxide metabolic process 18
              negative regulation of hydrogen peroxide metabolic process + 7
              positive regulation of hydrogen peroxide metabolic process + 7
              regulation of hydrogen peroxide biosynthetic process + 9
              regulation of hydrogen peroxide catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 11968
    biological regulation 8764
      regulation of biological process 8316
        regulation of metabolic process 5088
          regulation of cellular metabolic process 4554
            regulation of reactive oxygen species metabolic process 201
              regulation of hydrogen peroxide metabolic process 18
                negative regulation of hydrogen peroxide metabolic process + 7
                positive regulation of hydrogen peroxide metabolic process + 7
                regulation of hydrogen peroxide biosynthetic process + 9
                regulation of hydrogen peroxide catabolic process + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.