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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3-K36 methylation
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Accession:GO:0010452 term browser browse the term
Definition:The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.
Synonyms:exact_synonym: histone H3K36me;   histone lysine H3 K36 methylation


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histone H3-K36 methylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100910833 histone-lysine N-methyltransferase setd3-like IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:131,602,149...131,650,424
Ensembl chr 6:131,602,413...131,648,661
JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr17:9,840,859...9,955,391
Ensembl chr17:9,844,133...9,952,898
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO (MGI:MGI:3850584|PMID:19483677), (MGI:MGI:5462481|PMID:23241889) RGD PMID:19483677, PMID:23241889 MGI:MGI:3850584, MGI:MGI:5462481 NCBI chr14:82,119,210...82,196,501
Ensembl chr14:82,119,210...82,171,480
JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:71,126,276...71,237,118
Ensembl chr16:71,130,668...71,237,118
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO MGI:MGI:4437211 (MGI:MGI:3772493|PMID:18157086), (MGI:MGI:4431136|PMID:20133625) RGD PMID:18157086, PMID:20133625 MGI:MGI:3772493, MGI:MGI:4431136 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setd3 SET domain containing 3, actin histidine methyltransferase IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:132,023,128...132,090,072
Ensembl chr 6:132,023,945...132,075,875
JBrowse link
G Setmar SET domain and mariner transposase fusion gene ISS
ISO
GO_REF:0000024
(PMID:16332963), (PMID:22231448)
UniProt
RGD
PMID:16332963, PMID:22231448 GO_REF:0000024 NCBI chr 4:140,092,346...140,104,495
Ensembl chr 4:140,092,352...140,105,316
JBrowse link
G Smyd2 SET and MYND domain containing 2 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:108,642,156...108,686,293
Ensembl chr13:108,642,156...108,686,290
JBrowse link
histone H3-K36 dimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash1l ASH1 like histone lysine methyltransferase ISO (PMID:26002201) RGD PMID:26002201 NCBI chr 2:188,252,592...188,389,251
Ensembl chr 2:188,253,220...188,389,250
JBrowse link
G Prdm9 PR/SET domain 9 ISO
ISS
(PMID:24634223)
(MGI:MGI:5784565|PMID:27362481)
GO_REF:0000024
RGD
UniProt
PMID:24634223, PMID:27362481 GO_REF:0000024, MGI:MGI:5784565 NCBI chr 1:57,533,602...57,555,155
Ensembl chr 1:57,533,577...57,555,048
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:26002201) RGD PMID:26002201 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setmar SET domain and mariner transposase fusion gene ISO (PMID:21187428) RGD PMID:21187428 NCBI chr 4:140,092,346...140,104,495
Ensembl chr 4:140,092,352...140,105,316
JBrowse link
histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prdm9 PR/SET domain 9 ISS
ISO
GO_REF:0000024
(MGI:MGI:5784565|PMID:27362481)
UniProt
RGD
PMID:27362481 GO_REF:0000024, MGI:MGI:5784565 NCBI chr 1:57,533,602...57,555,155
Ensembl chr 1:57,533,577...57,555,048
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO (PMID:19141475), (PMID:23043551), (PMID:23325844), (PMID:23622243), (PMID:24843002), (PMID:26002201), (PMID:27474439), (PMID:28753426)
(MGI:MGI:5528755|PMID:24036311), (MGI:MGI:5908786|PMID:25242323)
RGD PMID:19141475, PMID:23043551, PMID:23325844, PMID:23622243, PMID:24036311, PMID:24843002, PMID:25242323, PMID:26002201, PMID:27474439, PMID:28753426 MGI:MGI:5528755, MGI:MGI:5908786 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setd5 SET domain containing 5 ISO (MGI:MGI:6381850|PMID:31515109) RGD PMID:31515109 MGI:MGI:6381850 NCBI chr 4:145,017,549...145,095,247
Ensembl chr 4:145,017,608...145,095,245
JBrowse link
negative regulation of histone H3-K36 methylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcor BCL6 co-repressor ISO (PMID:19578371) RGD PMID:19578371 NCBI chr  X:11,570,155...11,692,022
Ensembl chr  X:11,648,989...11,691,099
JBrowse link
G Fh fumarate hydratase ISS
ISO
GO_REF:0000024
(PMID:26237645)
UniProt
RGD
PMID:26237645 GO_REF:0000024 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
positive regulation of histone H3-K36 methylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paxip1 PAX interacting protein 1 ISO (MGI:MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:MGI:4821506 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326
JBrowse link
positive regulation of histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 ISO (PMID:21555454) RGD PMID:21555454 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 ISO (PMID:21555454) RGD PMID:21555454 NCBI chr16:71,126,276...71,237,118
Ensembl chr16:71,130,668...71,237,118
JBrowse link
G Prdm9 PR/SET domain 9 ISO
ISS
(PMID:24634223)
GO_REF:0000024
RGD
UniProt
PMID:24634223 GO_REF:0000024 NCBI chr 1:57,533,602...57,555,155
Ensembl chr 1:57,533,577...57,555,048
JBrowse link
regulation of histone H3-K36 methylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsd1 nuclear receptor binding SET domain protein 1 ISO (PMID:20837538) RGD PMID:20837538 NCBI chr17:9,840,859...9,955,391
Ensembl chr17:9,844,133...9,952,898
JBrowse link
regulation of histone H3-K36 trimethylation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iws1 interacts with SUPT6H, CTD assembly factor 1 IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(PMID:19141475)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19141475, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr18:24,849,508...24,891,339
Ensembl chr18:24,849,545...24,880,317
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      methylation 369
        macromolecule methylation 334
          protein methylation 204
            peptidyl-lysine methylation 143
              histone lysine methylation 128
                histone H3-K36 methylation 16
                  histone H3-K36 dimethylation 4
                  histone H3-K36 trimethylation + 6
                  negative regulation of histone H3-K36 methylation + 2
                  positive regulation of histone H3-K36 methylation + 4
                  regulation of histone H3-K36 methylation + 8
Path 2
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      organic substance metabolic process 11639
        organonitrogen compound metabolic process 7135
          protein metabolic process 6217
            cellular protein metabolic process 5555
              cellular protein modification process 3939
                peptidyl-amino acid modification 1317
                  peptidyl-lysine modification 414
                    peptidyl-lysine methylation 143
                      histone lysine methylation 128
                        histone H3-K36 methylation 16
                          histone H3-K36 dimethylation 4
                          histone H3-K36 trimethylation + 6
                          negative regulation of histone H3-K36 methylation + 2
                          positive regulation of histone H3-K36 methylation + 4
                          regulation of histone H3-K36 methylation + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.