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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cell fate commitment
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Accession:GO:0010453 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.


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regulation of cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Gdf3 growth differentiation factor 3 JBrowse link 4 155,417,667 155,422,014 RGD:1624291
RGD:1600115
G Pax7 paired box 7 JBrowse link 5 158,211,001 158,313,510 RGD:1624291
RGD:1600115
G Zfp157 zinc finger protein 157 JBrowse link 12 18,461,283 18,495,871 RGD:1624291
RGD:1600115
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1624291
RGD:1600115
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
negative regulation of cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glis1 GLIS family zinc finger 1 JBrowse link 5 127,043,344 127,233,395 RGD:1600115
RGD:1624291
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:1624291
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Sostdc1 sclerostin domain containing 1 JBrowse link 6 55,812,820 55,816,994 RGD:1624291
RGD:1600115
G Spdef SAM pointed domain containing ets transcription factor JBrowse link 20 7,292,823 7,308,053 RGD:1624291
RGD:1600115
negative regulation of cell fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
negative regulation of cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fzd7 frizzled class receptor 7 JBrowse link 9 66,305,731 66,308,550 RGD:1624291
RGD:1600115
negative regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
RGD:1600115
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
negative regulation of retinal cone cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casz1 castor zinc finger 1 JBrowse link 5 165,625,119 165,777,053 RGD:1624291
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
RGD:1600115
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
RGD:1600115
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
RGD:1600115
positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
positive regulation of cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkx6-2 NK6 homeobox 2 JBrowse link 1 211,922,389 211,923,929 RGD:1624291
RGD:1600115
G Spdef SAM pointed domain containing ets transcription factor JBrowse link 20 7,292,823 7,308,053 RGD:1624291
RGD:1600115
positive regulation of cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:729590
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:13792537
regulation of cardiac cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
RGD:1600115
regulation of cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lmo4 LIM domain only 4 JBrowse link 2 250,218,635 250,235,435 RGD:1624291
RGD:1600115
regulation of endodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esrp1 epithelial splicing regulatory protein 1 JBrowse link 5 24,576,988 24,631,758 RGD:1600115
RGD:1624291
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
regulation of mesodermal cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:1624291
regulation of neural crest cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
site-specific DNA replication termination at RTS1 barrier term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rtfdc1 replication termination factor 2 domain containing 1 JBrowse link 3 170,443,895 170,473,456 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    regulation of biological process 12516
      regulation of cellular process 11839
        regulation of cell differentiation 1969
          regulation of cell fate commitment 32
            negative regulation of cell fate commitment + 17
            positive regulation of cell fate commitment + 8
            regulation of T-helper 17 cell lineage commitment + 4
            regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 2
            regulation of cell fate determination + 1
            regulation of cell fate specification + 15
            regulation of mating type switching + 1
            regulation of retinal cone cell fate commitment + 1
            regulation of retinal rod cell fate commitment + 0
            regulation of sevenless signaling pathway + 0
            regulation of trichome patterning + 0
            regulation of venous endothelial cell fate commitment + 0
Path 2
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cellular developmental process 4400
        cell differentiation 4180
          cell fate commitment 282
            regulation of cell fate commitment 32
              negative regulation of cell fate commitment + 17
              positive regulation of cell fate commitment + 8
              regulation of T-helper 17 cell lineage commitment + 4
              regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment + 2
              regulation of cell fate determination + 1
              regulation of cell fate specification + 15
              regulation of mating type switching + 1
              regulation of retinal cone cell fate commitment + 1
              regulation of retinal rod cell fate commitment + 0
              regulation of sevenless signaling pathway + 0
              regulation of trichome patterning + 0
              regulation of venous endothelial cell fate commitment + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.