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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of heart rate
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Accession:GO:0010459 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency or rate of heart contraction.


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negative regulation of heart rate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO (MGI:MGI:3626025|PMID:9449684) RGD PMID:9449684 MGI:MGI:3626025 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B ISO (MGI:MGI:3621834|PMID:12837242) RGD PMID:12837242 MGI:MGI:3621834 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Npff neuropeptide FF-amide peptide precursor IDA RGD PMID:8680863 RGD:2316573 NCBI chr 7:144,127,084...144,127,873
Ensembl chr 7:144,127,085...144,127,873
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IMP RGD PMID:19015400 RGD:4108483 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pln phospholamban ISO (PMID:16432188) RGD PMID:16432188 NCBI chr20:34,633,157...34,642,904
Ensembl chr20:34,633,157...34,642,904
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO (PMID:15841207) RGD PMID:15841207 NCBI chr 1:251,828,285...252,101,963
Ensembl chr 1:251,828,290...252,100,759
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 ISO MGI:MGI:1856134 (MGI:MGI:4837024|PMID:20877009) RGD PMID:20877009 MGI:MGI:4837024 NCBI chr 1:84,168,494...84,254,679
Ensembl chr 1:84,168,495...84,254,645
JBrowse link
G Spx spexin hormone IDA PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr 4:176,629,597...176,635,698
Ensembl chr 4:176,629,800...176,641,008
JBrowse link
G Sri sorcin ISO (PMID:12754254) RGD PMID:12754254 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
G Tac1 tachykinin, precursor 1 IDA RGD PMID:2471579 RGD:2305984 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:7875478 RGD:14975128 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:27335281 RGD:13792700 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:12217424 RGD:2306871 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:9316844 RGD:2303391 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A ISO MGI:MGI:2387663 (MGI:MGI:2182494|PMID:12093905) RGD PMID:12093905 MGI:MGI:2182494 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological quality 4283
        regulation of heart rate 109
          negative regulation of heart rate 15
            negative regulation of heart rate by acetylcholine + 1
            negative regulation of heart rate in other organism 0
            negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
Path 2
Term Annotations click to browse term
  biological_process 20017
    multicellular organismal process 9055
      system process 3445
        circulatory system process 578
          heart process 255
            heart contraction 246
              regulation of heart contraction 200
                regulation of heart rate 109
                  negative regulation of heart rate 15
                    negative regulation of heart rate by acetylcholine + 1
                    negative regulation of heart rate in other organism 0
                    negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.