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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of gastrulation
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Accession:GO:0010470 term browser browse the term
Definition:Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.


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regulation of gastrulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLASP1 cytoplasmic linker associated protein 1 IEA Ensembl GO_REF:0000107 NCBI chr15:29,782,613...30,042,727
Ensembl chr15:29,782,604...30,042,734
JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 IEA Ensembl GO_REF:0000107 NCBI chr13:19,305,430...19,510,589
Ensembl chr13:19,305,180...19,510,585
JBrowse link
G CRB2 crumbs cell polarity complex component 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:264,277,549...264,301,731
Ensembl chr 1:264,276,572...264,301,725
JBrowse link
G DAG1 dystroglycan 1 IEA Ensembl GO_REF:0000107 NCBI chr13:32,028,019...32,092,450
Ensembl chr13:32,029,329...32,092,453
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha IEA Ensembl GO_REF:0000107 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G NODAL nodal growth differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr14:73,350,358...73,357,064
Ensembl chr14:73,349,965...73,360,618
JBrowse link
G PHLDB1 pleckstrin homology like domain family B member 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:45,902,099...45,949,415
Ensembl chr 9:45,902,105...45,949,417
JBrowse link
G PHLDB2 pleckstrin homology like domain family B member 2 IEA Ensembl GO_REF:0000107 NCBI chr13:147,778,420...148,025,943
Ensembl chr13:147,778,053...148,087,744
JBrowse link
G PLCXD2 phosphatidylinositol specific phospholipase C X domain containing 2 IEA Ensembl GO_REF:0000107 NCBI chr13:148,033,712...148,087,766
Ensembl chr13:147,778,053...148,087,744
JBrowse link
G POGLUT1 protein O-glucosyltransferase 1 IEA Ensembl GO_REF:0000107 NCBI chr13:140,763,231...140,793,645
Ensembl chr13:140,764,185...140,793,596
JBrowse link
G TGIF1 TGFB induced factor homeobox 1 ISO (MGI:MGI:4430444|PMID:20040491) MGI PMID:20040491 MGI:MGI:4430444 NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,397...103,235,856
JBrowse link
G TGIF2 TGFB induced factor homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr17:39,840,649...39,858,162
Ensembl chr17:39,675,084...39,858,159
JBrowse link
negative regulation of ectodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FZD7 frizzled class receptor 7 IEA Ensembl GO_REF:0000107 NCBI chr15:105,644,164...105,648,860
Ensembl chr15:105,644,188...105,648,854
JBrowse link
negative regulation of endodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL5A1 collagen type V alpha 1 chain IEA Ensembl GO_REF:0000107 NCBI chr 1:273,934,219...274,083,264
Ensembl chr 1:273,971,971...274,085,426
JBrowse link
G COL5A2 collagen type V alpha 2 chain IEA Ensembl GO_REF:0000107 NCBI chr15:93,611,856...93,981,131
Ensembl chr15:93,611,856...93,981,110
JBrowse link
negative regulation of endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MESP1 mesoderm posterior bHLH transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:55,322,016...55,327,600
Ensembl chr 7:55,322,010...55,325,732
JBrowse link
negative regulation of heterotypic cell-cell adhesion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IEA
ISS
Ensembl
UniProt
GO_REF:0000024, GO_REF:0000107 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G APOA1 apolipoprotein A1 IEA Ensembl GO_REF:0000107 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,393...44,218,978
JBrowse link
G IL10 interleukin 10 IEA Ensembl GO_REF:0000107 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO (PMID:2139180) BHF-UCL PMID:2139180
G KLF4 Kruppel like factor 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:248,604,817...248,609,574
Ensembl chr 1:248,604,820...248,609,574
JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 1:165,458,263...165,733,452
Ensembl chr 1:165,458,258...165,740,319
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 IEA Ensembl GO_REF:0000107 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,128,686...60,149,270
JBrowse link
G MBP myelin basic protein ISO (PMID:22524708) CAFA PMID:22524708 NCBI chr 1:147,649,516...147,685,289
Ensembl chr 1:147,568,673...147,685,288
JBrowse link
G MYADM myeloid associated differentiation marker ISO (PMID:23264465) UniProtKB PMID:23264465 NCBI chr 6:56,236,306...56,278,577
Ensembl chr 6:56,236,306...56,278,582
JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 ISO (PMID:27400149) BHF-UCL PMID:27400149 NCBI chr 5:68,000,792...68,142,533
Ensembl chr 5:68,001,104...68,140,757
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IEA Ensembl GO_REF:0000107 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,450
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:55,322,016...55,327,600
Ensembl chr 7:55,322,010...55,325,732
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,133...75,345,926
JBrowse link
positive regulation of endodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2AFY H2A histone family, member Y IEA Ensembl GO_REF:0000107 NCBI chr 2:137,535,128...137,623,886
Ensembl chr 2:137,535,131...137,623,889
JBrowse link
positive regulation of gastrulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXA2 forkhead box A2 ISO (MGI:MGI:2157654|PMID:11291865) UniProtKB PMID:11291865 MGI:MGI:2157654 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,400...30,001,707
JBrowse link
G LHX1 LIM homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr12:38,450,708...38,457,583
Ensembl chr12:38,450,708...38,456,139
JBrowse link
G OSR1 odd-skipped related transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:118,368,471...118,765,107
Ensembl chr 3:118,521,296...118,932,446
JBrowse link
G OSR2 odd-skipped related transciption factor 2 ISO (MGI:MGI:5009762|PMID:21281489) UniProtKB PMID:21281489 MGI:MGI:5009762 NCBI chr 4:37,890,200...37,897,935
Ensembl chr 4:37,852,587...37,897,935
JBrowse link
G OTX2 orthodenticle homeobox 2 ISO (MGI:MGI:2157654|PMID:11291865) UniProtKB PMID:11291865 MGI:MGI:2157654 NCBI chr 1:186,028,575...186,039,026
Ensembl chr 1:186,028,575...186,038,229
JBrowse link
G RACK1 receptor for activated C kinase 1 ISS UniProt GO_REF:0000024 NCBI chr 2:57,280,192...57,284,846
Ensembl chr 2:57,279,857...57,284,855
JBrowse link
G SCX scleraxis bHLH transcription factor ISO (MGI:MGI:1343990|PMID:10477299) UniProtKB PMID:10477299 MGI:MGI:1343990 NCBI chr 4:500,884...503,276
Ensembl chr 4:501,172...502,994
JBrowse link
G TENM4 teneurin transmembrane protein 4 ISO (MGI:MGI:3531238|PMID:15489520) UniProtKB PMID:15489520 MGI:MGI:3531238 NCBI chr 9:13,040,615...13,826,957 JBrowse link
positive regulation of mesodermal cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,515...41,002,137
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT3A Wnt family member 3A IEA Ensembl GO_REF:0000107 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,154,086...51,202,176
JBrowse link
regulation of endodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IEA Ensembl GO_REF:0000107 NCBI chr14:97,487,854...97,490,118
Ensembl chr14:97,487,226...97,490,450
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1A bone morphogenetic protein receptor type 1A IEA Ensembl GO_REF:0000107 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,793
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,746
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    developmental process 6285
      anatomical structure morphogenesis 2766
        regulation of anatomical structure morphogenesis 1097
          regulation of gastrulation 41
            negative regulation of gastrulation + 6
            positive regulation of gastrulation + 11
            regulation of apical constriction involved in ventral furrow formation + 0
            regulation of cell-cell adhesion involved in gastrulation + 10
            regulation of convergent extension involved in gastrulation + 0
            regulation of ectodermal cell fate specification + 1
            regulation of endodermal cell differentiation + 5
            regulation of epiboly involved in gastrulation with mouth forming second + 0
            regulation of mesoderm formation + 7
            regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 0
Path 2
Term Annotations click to browse term
  biological_process 16524
    developmental process 6285
      anatomical structure development 5826
        multicellular organism development 5330
          embryo development 1253
            embryonic morphogenesis 665
              gastrulation 193
                regulation of gastrulation 41
                  negative regulation of gastrulation + 6
                  positive regulation of gastrulation + 11
                  regulation of apical constriction involved in ventral furrow formation + 0
                  regulation of cell-cell adhesion involved in gastrulation + 10
                  regulation of convergent extension involved in gastrulation + 0
                  regulation of ectodermal cell fate specification + 1
                  regulation of endodermal cell differentiation + 5
                  regulation of epiboly involved in gastrulation with mouth forming second + 0
                  regulation of mesoderm formation + 7
                  regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.