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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of double-strand break repair via homologous recombination
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Accession:GO:0010569 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.


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regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:1624291
RGD:1600115
G Fign fidgetin, microtubule severing factor JBrowse link 3 49,992,250 50,120,601 RGD:13792537
G Fignl1 fidgetin-like 1 JBrowse link 14 91,895,902 91,904,474 RGD:1624291
RGD:13792537
RGD:1600115
G Kdm1a lysine demethylase 1A JBrowse link 5 154,909,003 154,965,171 RGD:1624291
G Ppp4c protein phosphatase 4, catalytic subunit JBrowse link 1 198,219,012 198,225,775 RGD:1600115
RGD:1624291
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 4 133,285,552 133,323,755 RGD:1624291
G Rad51 RAD51 recombinase JBrowse link 3 110,918,240 110,942,920 RGD:1624291
G Rad51ap1 RAD51 associated protein 1 JBrowse link 4 159,469,803 159,482,869 RGD:1624291
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1624291
RGD:1600115
G Rtel1 regulator of telomere elongation helicase 1 JBrowse link 3 176,818,012 176,856,531 RGD:1624291
RGD:13792537
RGD:1600115
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:1624291
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1624291
G Spidr scaffold protein involved in DNA repair JBrowse link 11 89,009,931 89,260,361 RGD:1624291
G Terf2ip TERF2 interacting protein JBrowse link 19 44,231,317 44,238,406 RGD:1624291
RGD:1600115
G Tex15 testis expressed 15, meiosis and synapsis associated JBrowse link 16 62,313,284 62,373,288 RGD:1624291
G Usp51 ubiquitin specific peptidase 51 JBrowse link X 19,268,352 19,273,753 RGD:1624291
G Zfp365 zinc finger protein 365 JBrowse link 20 22,060,160 22,083,766 RGD:1624291
RGD:1600115
negative regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
RGD:13792537
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fbh1 F-box DNA helicase 1 JBrowse link 17 70,399,093 70,437,151 RGD:1624291
G Helb DNA helicase B JBrowse link 7 64,860,641 64,888,146 RGD:1624291
RGD:13792537
G Klhl15 kelch-like family member 15 JBrowse link X 63,342,277 63,390,915 RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Parpbp PARP1 binding protein JBrowse link 7 28,654,707 28,724,412 RGD:1624291
RGD:1600115
G Polq DNA polymerase theta JBrowse link 11 66,585,860 66,695,369 RGD:1624291
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:1624291
RGD:1600115
G Recql5 RecQ like helicase 5 JBrowse link 10 104,443,735 104,482,889 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Rmi2 RecQ mediated genome instability 2 JBrowse link 10 4,904,458 4,910,339 RGD:13792537
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 JBrowse link 9 119,675,750 119,818,620 RGD:1624291
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
G Ubqln4 ubiquilin 4 JBrowse link 2 187,915,701 187,931,035 RGD:1624291
positive regulation of double-strand break repair via homologous recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 actin related protein 2 JBrowse link 14 104,338,486 104,375,840 RGD:1600115
RGD:1624291
G Arid2 AT-rich interaction domain 2 JBrowse link 7 137,680,564 137,798,329 RGD:1600115
RGD:1624291
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:1624291
G Fancb FA complementation group B JBrowse link X 31,124,018 31,140,790 RGD:1624291
RGD:13792537
G Fus FUS RNA binding protein JBrowse link 1 199,412,805 199,426,705 RGD:1624291
G Mms19 MMS19 homolog, cytosolic iron-sulfur assembly component JBrowse link 1 261,191,646 261,229,070 RGD:1624291
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1600115
RGD:1624291
G Timeless timeless circadian regulator JBrowse link 7 2,643,288 2,667,329 RGD:1600115
RGD:1624291
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1624291
G Wrap53 WD repeat containing, antisense to TP53 JBrowse link 10 56,169,024 56,185,800 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      regulation of metabolic process 6582
        regulation of macromolecule metabolic process 6057
          regulation of DNA metabolic process 384
            regulation of DNA recombination 107
              regulation of double-strand break repair via homologous recombination 45
                negative regulation of double-strand break repair via homologous recombination + 17
                positive regulation of double-strand break repair via homologous recombination 12
                regulation of double-strand break repair via break-induced replication + 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      cellular metabolic process 10644
        cellular aromatic compound metabolic process 5507
          nucleobase-containing compound metabolic process 5278
            nucleic acid metabolic process 4788
              DNA metabolic process 885
                DNA repair 473
                  recombinational repair 134
                    double-strand break repair via homologous recombination 133
                      regulation of double-strand break repair via homologous recombination 45
                        negative regulation of double-strand break repair via homologous recombination + 17
                        positive regulation of double-strand break repair via homologous recombination 12
                        regulation of double-strand break repair via break-induced replication + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.