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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chr 4:51,648,293...51,941,329
Ensembl chr 4:57,966,197...58,259,404
JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 ISO (PMID:21724588) UniProtKB PMID:21724588 NCBI chr16:37,896,177...37,942,040
Ensembl chr16:57,036,425...57,074,221
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO (PMID:12958148) BHF-UCL PMID:12958148 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G IL1B interleukin 1 beta ISO (PMID:12794819) UniProt PMID:12794819 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL6 interleukin 6 ISO (PMID:12794819) UniProt PMID:12794819 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G TNF tumor necrosis factor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23804076 RGD:10402115 NCBI chr13:9,584,850...9,779,542 JBrowse link
G NUTF2 nuclear transport factor 2 ISO RGD PMID:19404486 RGD:9831377 NCBI chr16:48,188,533...48,214,205
Ensembl chr16:67,575,842...67,601,053
JBrowse link
G SARS1 seryl-tRNA synthetase 1 ISO (PMID:24940000) UniProtKB PMID:24940000 NCBI chr 1:111,590,850...111,615,068
Ensembl chr 1:110,755,054...110,779,704
JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:MGI:3806198|PMID:18559975) MGI PMID:18559975 MGI:MGI:3806198 NCBI chr17:34,849,466...34,880,088 JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator ISO (PMID:8756616) BHF-UCL PMID:8756616 NCBI chr 1:126,160,017...126,226,222
Ensembl chr 1:129,809,431...129,875,629
JBrowse link
G ATF4 activating transcription factor 4 ISO (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO (PMID:23415688) BHF-UCL PMID:23415688 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815
JBrowse link
G C3 complement C3 ISO (PMID:16452172) BHF-UCL PMID:16452172 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C3AR1 complement C3a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chr12:8,178,064...8,186,206
Ensembl chr12:8,220,933...8,222,381
JBrowse link
G C5 complement C5 ISO (PMID:14566334), (PMID:16452172) BHF-UCL PMID:14566334, PMID:16452172 NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856
JBrowse link
G C5AR1 complement C5a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chr19:44,293,612...44,310,430
Ensembl chr19:52,950,317...52,966,146
JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chr18:52,819,591...53,087,772
Ensembl chr18:56,149,036...56,412,222
JBrowse link
G CXCL17 C-X-C motif chemokine ligand 17 ISO (PMID:23115081) UniProtKB PMID:23115081 NCBI chr19:39,315,929...39,331,651
Ensembl chr19:47,908,179...47,922,120
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO (MGI:MGI:5492227|PMID:23568032) UniProtKB PMID:23568032 MGI:MGI:5492227 NCBI chr2A:38,087,863...38,096,529 JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:5607215|PMID:22915762)
(PMID:22915762)
ParkinsonsUK-UCL PMID:22915762 MGI:MGI:5607215 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 ISO (PMID:19779139) UniProtKB PMID:19779139 NCBI chr 5:175,804,728...175,852,703
Ensembl chr 5:183,115,856...183,149,006
JBrowse link
G GATA4 GATA binding protein 4 ISO (MGI:MGI:3763665|PMID:17975667) BHF-UCL PMID:17975667 MGI:MGI:3763665 NCBI chr 8:7,442,921...7,526,731 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO (PMID:8756616)
(PMID:18658046)
BHF-UCL
UniProtKB
PMID:8756616, PMID:18658046 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HPSE heparanase ISO (PMID:16452201) UniProtKB PMID:16452201 NCBI chr 4:40,863,491...40,905,693
Ensembl chr 4:46,709,621...46,755,157
JBrowse link
G IL1A interleukin 1 alpha ISO (MGI:MGI:2652930|PMID:12598651) BHF-UCL PMID:12598651 MGI:MGI:2652930 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO (PMID:12958148)
(MGI:MGI:2652930|PMID:12598651)
BHF-UCL PMID:12598651, PMID:12958148 MGI:MGI:2652930 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL6 interleukin 6 ISO (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ISL1 ISL LIM homeobox 1 ISO (MGI:MGI:5437583|PMID:22727192) BHF-UCL PMID:22727192 MGI:MGI:5437583 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674
JBrowse link
G NODAL nodal growth differentiation factor ISO (PMID:21116837) BHF-UCL PMID:21116837 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972
JBrowse link
G NOX1 NADPH oxidase 1 ISO (PMID:11805326) BHF-UCL PMID:11805326 NCBI chr  X:90,046,023...90,076,968
Ensembl chr  X:100,182,398...100,215,192
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G RORA RAR related orphan receptor A ISO (PMID:18658046) UniProtKB PMID:18658046 NCBI chr15:39,461,553...40,200,118
Ensembl chr15:57,771,735...57,980,460
JBrowse link
G SULF1 sulfatase 1 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chr 8:65,992,961...66,194,112
Ensembl chr 8:67,744,801...67,848,704
JBrowse link
G SULF2 sulfatase 2 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chr20:43,992,927...44,122,598
Ensembl chr20:45,074,069...45,173,893
JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chr18:20,108,607...20,122,381
Ensembl chr18:23,713,146...23,726,919
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO (MGI:MGI:3840068|PMID:14566334) BHF-UCL PMID:14566334 MGI:MGI:3840068 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO (MGI:MGI:3840068|PMID:14566334) BHF-UCL PMID:14566334 MGI:MGI:3840068 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G IL6 interleukin 6 ISO (PMID:8557680) BHF-UCL PMID:8557680 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G NDRG2 NDRG family member 2 ISO (MGI:MGI:4835375|PMID:19815093) MGI PMID:19815093 MGI:MGI:4835375 NCBI chr14:1,831,764...1,840,819
Ensembl chr14:19,913,674...19,967,470
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    multicellular organismal process 6470
      cytokine production 701
        vascular endothelial growth factor production 37
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 26
          regulation of vascular endothelial growth factor production + 33
Path 2
Term Annotations click to browse term
  biological_process 12561
    metabolic process 7977
      organic substance metabolic process 7668
        macromolecule metabolic process 6621
          gene expression 4111
            cytokine production 701
              vascular endothelial growth factor production 37
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 26
                regulation of vascular endothelial growth factor production + 33
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.