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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts3 ADAM metallopeptidase with thrombospondin type 1 motif 3 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chrNW_004955447:803,287...1,036,435
Ensembl chrNW_004955447:803,057...1,036,485
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 ISO (PMID:21724588) UniProtKB PMID:21724588 NCBI chrNW_004955433:15,253,196...15,288,982
Ensembl chrNW_004955433:15,259,720...15,289,151
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (PMID:12958148) BHF-UCL PMID:12958148 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Il1b interleukin 1 beta ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il6 interleukin 6 ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23804076 RGD:10402115 NCBI chrNW_004955497:7,653,309...7,831,737
Ensembl chrNW_004955497:7,653,248...7,831,472
JBrowse link
G Nutf2 nuclear transport factor 2 ISO RGD PMID:19404486 RGD:9831377 NCBI chrNW_004955484:8,832,871...8,854,151
Ensembl chrNW_004955484:8,832,871...8,854,135
JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO (PMID:24940000) UniProtKB PMID:24940000 NCBI chrNW_004955435:12,642,485...12,659,833
Ensembl chrNW_004955435:12,641,776...12,660,682
JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO (MGI:MGI:3806198|PMID:18559975) MGI PMID:18559975 MGI:MGI:3806198 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO (PMID:8756616) BHF-UCL PMID:8756616 NCBI chrNW_004955588:159,462...233,047
Ensembl chrNW_004955588:159,462...233,047
JBrowse link
G Atf4 activating transcription factor 4 ISO (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218
JBrowse link
G Brca1 BRCA1 DNA repair associated ISO (PMID:23415688) BHF-UCL PMID:23415688 NCBI chrNW_004955451:16,819,463...16,870,780 JBrowse link
G Bsg basigin (Ok blood group) ISO (PMID:19837976)
(PMID:15833850)
UniProt PMID:15833850, PMID:19837976 NCBI chrNW_004955495:7,148,806...7,156,296 JBrowse link
G C3 complement C3 ISO (PMID:16452172) BHF-UCL PMID:16452172 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G C3ar1 complement C3a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chrNW_004955413:6,707,003...6,715,689
Ensembl chrNW_004955413:6,707,689...6,715,689
JBrowse link
G C5ar1 complement C5a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chrNW_004955574:1,221,942...1,229,634
Ensembl chrNW_004955574:1,221,187...1,231,655
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chrNW_004955402:43,551,810...43,819,731
Ensembl chrNW_004955402:43,555,924...43,819,706
JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 ISO (PMID:23115081) UniProtKB PMID:23115081 NCBI chrNW_004955555:495,437...509,788
Ensembl chrNW_004955555:495,445...509,788
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (PMID:22915762)
(MGI:MGI:5607215|PMID:22915762)
ParkinsonsUK-UCL PMID:22915762 MGI:MGI:5607215 NCBI chrNW_004955424:210,867...279,267
Ensembl chrNW_004955424:226,038...280,593
JBrowse link
G Flt4 fms related receptor tyrosine kinase 4 ISO (PMID:19779139) UniProtKB PMID:19779139 NCBI chrNW_004955408:98,995...137,922
Ensembl chrNW_004955408:107,056...140,056
JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:MGI:3763665|PMID:17975667) BHF-UCL PMID:17975667 MGI:MGI:3763665 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (PMID:18658046)
(PMID:8756616)
UniProtKB
BHF-UCL
PMID:8756616, PMID:18658046 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497
JBrowse link
G Hpse heparanase ISO (PMID:16452201) UniProtKB PMID:16452201 NCBI chrNW_004955474:6,367,467...6,394,395
Ensembl chrNW_004955474:6,367,467...6,394,395
JBrowse link
G Il1a interleukin 1 alpha ISO (MGI:MGI:2652930|PMID:12598651) BHF-UCL PMID:12598651 MGI:MGI:2652930 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Il1b interleukin 1 beta ISO (MGI:MGI:2652930|PMID:12598651)
(PMID:12958148)
BHF-UCL PMID:12598651, PMID:12958148 MGI:MGI:2652930 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il6 interleukin 6 ISO (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:MGI:5437583|PMID:22727192) BHF-UCL PMID:22727192 MGI:MGI:5437583 NCBI chrNW_004955446:15,824,956...15,835,000
Ensembl chrNW_004955446:15,824,035...15,835,046
JBrowse link
G LOC102009223 cytochrome P450 1B1 ISO (MGI:MGI:5492227|PMID:23568032) UniProtKB PMID:23568032 MGI:MGI:5492227 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131
JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:21116837) BHF-UCL PMID:21116837 NCBI chrNW_004955437:20,828,448...20,835,486
Ensembl chrNW_004955437:20,828,448...20,835,628
JBrowse link
G Nox1 NADPH oxidase 1 ISO (PMID:11805326) BHF-UCL PMID:11805326 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Rora RAR related orphan receptor A ISO (PMID:18658046) UniProtKB PMID:18658046 NCBI chrNW_004955450:14,262,199...14,434,611
Ensembl chrNW_004955450:14,262,190...14,425,233
JBrowse link
G Sulf1 sulfatase 1 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chrNW_004955444:9,902,334...10,066,929
Ensembl chrNW_004955444:9,899,941...9,974,666
JBrowse link
G Sulf2 sulfatase 2 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chrNW_004955445:9,919,472...10,020,491
Ensembl chrNW_004955445:9,920,789...10,020,491
JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO (MGI:MGI:3840068|PMID:14566334) BHF-UCL PMID:14566334 MGI:MGI:3840068 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Il6 interleukin 6 ISO (PMID:8557680) BHF-UCL PMID:8557680 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Ndrg2 NDRG family member 2 ISO (MGI:MGI:4835375|PMID:19815093) MGI PMID:19815093 MGI:MGI:4835375 NCBI chrNW_004955550:1,771,514...1,778,693
Ensembl chrNW_004955550:1,767,911...1,780,635
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11889
    multicellular organismal process 6168
      cytokine production 641
        vascular endothelial growth factor production 36
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 26
          regulation of vascular endothelial growth factor production + 32
Path 2
Term Annotations click to browse term
  biological_process 11889
    metabolic process 7609
      organic substance metabolic process 7318
        macromolecule metabolic process 6345
          gene expression 3933
            cytokine production 641
              vascular endothelial growth factor production 36
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 26
                regulation of vascular endothelial growth factor production + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.