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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 IDA (PMID:24552833) BHF-UCL PMID:24552833 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221
JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 IDA (PMID:21724588) UniProtKB PMID:21724588 NCBI chr16:57,619,535...57,665,567
Ensembl chr16:57,610,652...57,665,580
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IDA (PMID:12958148) BHF-UCL PMID:12958148 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G IL1B interleukin 1 beta IDA (PMID:12794819) UniProt PMID:12794819 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 IDA (PMID:12794819) UniProt PMID:12794819 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6R interleukin 6 receptor IDA (PMID:12794819) UniProt PMID:12794819 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
JBrowse link
G TNF tumor necrosis factor IDA (PMID:12794819) UniProt PMID:12794819 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23804076 RGD:10402115 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G NUTF2 nuclear transport factor 2 IEA Ensembl GO_REF:0000107 NCBI chr16:67,846,933...67,872,567
Ensembl chr16:67,846,923...67,872,567
JBrowse link
G SARS1 seryl-tRNA synthetase 1 IDA (PMID:24940000) UniProtKB PMID:24940000 NCBI chr 1:109,213,893...109,238,182
Ensembl chr 1:109,213,918...109,238,182
JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor IEA Ensembl GO_REF:0000107 NCBI chr17:15,927,782...15,975,896
Ensembl chr17:15,944,917...15,975,746
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator IDA (PMID:8756616) BHF-UCL PMID:8756616 NCBI chr 1:150,809,713...150,876,737
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G ATF4 activating transcription factor 4 IMP (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,672...39,522,683
Ensembl chr22:39,519,672...39,522,683
JBrowse link
G BRCA1 BRCA1 DNA repair associated IMP (PMID:23415688) BHF-UCL PMID:23415688 NCBI chr17:43,044,295...43,125,364
Ensembl chr17:43,044,295...43,170,245
JBrowse link
G BSG basigin (Ok blood group) IMP
IDA
(PMID:15833850)
(PMID:19837976)
UniProt PMID:15833850, PMID:19837976 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,493
JBrowse link
G C3 complement C3 IDA (PMID:16452172) BHF-UCL PMID:16452172 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C3AR1 complement C3a receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr12:8,056,844...8,066,359
Ensembl chr12:8,056,844...8,066,359
JBrowse link
G C5 complement C5 IDA (PMID:14566334), (PMID:16452172) BHF-UCL PMID:14566334, PMID:16452172 NCBI chr 9:120,952,335...121,074,865
Ensembl chr 9:120,952,335...121,050,275
Ensembl chr 9:120,952,335...121,050,275
JBrowse link
G C5AR1 complement C5a receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr19:47,309,861...47,322,066
Ensembl chr19:47,290,023...47,322,066
JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 IDA (PMID:24552833) BHF-UCL PMID:24552833 NCBI chr18:59,430,939...59,698,181
Ensembl chr18:59,430,939...59,697,662
JBrowse link
G CXCL17 C-X-C motif chemokine ligand 17 IMP
IBA
(PMID:23115081)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:23115081 NCBI chr19:42,428,278...42,442,946
Ensembl chr19:42,428,278...42,442,946
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISS UniProtKB GO_REF:0000024 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 IMP (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 IMP (PMID:19779139) UniProtKB PMID:19779139 NCBI chr 5:180,601,506...180,650,298
Ensembl chr 5:180,601,506...180,649,624
JBrowse link
G GATA4 GATA binding protein 4 ISS BHF-UCL GO_REF:0000024 NCBI chr 8:11,676,931...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IDA
IMP
(PMID:8756616)
(PMID:18658046)
BHF-UCL
UniProtKB
PMID:8756616, PMID:18658046 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HPSE heparanase IDA (PMID:16452201) UniProtKB PMID:16452201 NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153
JBrowse link
G IL1A interleukin 1 alpha ISS BHF-UCL GO_REF:0000024 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta IDA
ISS
(PMID:12958148) BHF-UCL PMID:12958148 GO_REF:0000024 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 IMP (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IL6ST interleukin 6 signal transducer TAS (PMID:10744750) BHF-UCL PMID:10744750 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
JBrowse link
G ISL1 ISL LIM homeobox 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G NODAL nodal growth differentiation factor IMP (PMID:21116837) BHF-UCL PMID:21116837 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link
G NOX1 NADPH oxidase 1 IEP (PMID:11805326) BHF-UCL PMID:11805326 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISS (PMID:9630216) BHF-UCL PMID:9630216 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RORA RAR related orphan receptor A IMP (PMID:18658046) UniProtKB PMID:18658046 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302
JBrowse link
G SULF1 sulfatase 1 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 8:69,466,624...69,660,912
Ensembl chr 8:69,466,624...69,660,915
JBrowse link
G SULF2 sulfatase 2 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr20:47,654,569...47,786,616
Ensembl chr20:47,656,348...47,786,616
JBrowse link
G TGFB1 transforming growth factor beta 1 TAS (PMID:19506300) BHF-UCL PMID:19506300 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO (MGI:MGI:3840068|PMID:14566334) BHF-UCL PMID:14566334 MGI:MGI:3840068 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,744...46,360,940
Ensembl chr 3:46,353,744...46,360,940
JBrowse link
G IL6 interleukin 6 IDA (PMID:8557680) BHF-UCL PMID:8557680 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G NDRG2 NDRG family member 2 IEA Ensembl GO_REF:0000107 NCBI chr14:21,016,763...21,070,872
Ensembl chr14:21,016,763...21,070,872
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    multicellular organismal process 8775
      cytokine production 831
        vascular endothelial growth factor production 40
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 29
          regulation of vascular endothelial growth factor production + 36
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12301
      organic substance metabolic process 11733
        macromolecule metabolic process 10186
          gene expression 6364
            cytokine production 831
              vascular endothelial growth factor production 40
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 29
                regulation of vascular endothelial growth factor production + 36
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.