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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 IEA Ensembl GO_REF:0000107 NCBI chr 8:68,675,067...68,948,537
Ensembl chr 8:68,675,070...68,948,455
JBrowse link
G ADGRG1 adhesion G protein-coupled receptor G1 IEA Ensembl GO_REF:0000107 NCBI chr 6:19,523,618...19,570,891
Ensembl chr 6:19,527,648...19,570,893
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G IL-6 interleukin-6 ISS UniProt GO_REF:0000024
G IL1B interleukin 1 beta ISS UniProt GO_REF:0000024 NCBI chr 3:43,670,126...43,677,125 JBrowse link
G IL6 interleukin 6 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G IL6R interleukin 6 receptor ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 4:95,322,426...95,381,393
Ensembl chr 4:95,322,426...95,381,282
JBrowse link
G LOC110258578 interleukin-1 beta-like ISO (PMID:12794819) UniProt PMID:12794819
G TNF tumor necrosis factor ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23804076 RGD:10402115 NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,620,700...5,795,264
JBrowse link
G NUTF2 nuclear transport factor 2 ISO RGD PMID:19404486 RGD:9831377 NCBI chr 6:28,469,274...28,489,007
Ensembl chr 6:28,469,505...28,489,007
JBrowse link
G SARS1 seryl-tRNA synthetase 1 ISO (PMID:24940000) UniProtKB PMID:24940000 NCBI chr 4:110,857,067...110,874,712
Ensembl chr 4:110,857,088...110,874,815
JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor IEA Ensembl GO_REF:0000107 NCBI chr12:59,431,834...59,449,701
Ensembl chr12:59,393,220...59,449,692
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator IEA Ensembl GO_REF:0000107 NCBI chr 4:98,333,431...98,390,012
Ensembl chr 4:98,333,459...98,404,961
JBrowse link
G ATF4 activating transcription factor 4 ISO (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,738,880...8,745,225
JBrowse link
G BRCA1 BRCA1 DNA repair associated IEA Ensembl GO_REF:0000107 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,855,570
JBrowse link
G BSG basigin ISO (PMID:19837976)
(PMID:15833850)
UniProt PMID:15833850, PMID:19837976 NCBI chr 2:77,735,586...77,743,451 JBrowse link
G C3 complement C3 IEA Ensembl GO_REF:0000107 NCBI chr 2:72,431,470...72,471,622
Ensembl chr 2:72,431,499...72,528,112
JBrowse link
G C3AR1 complement C3a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chr 5:63,088,778...63,098,750 JBrowse link
G C5 complement C5 IEA Ensembl GO_REF:0000107 NCBI chr 1:260,995,662...261,088,868
Ensembl chr 1:260,995,662...261,133,483
JBrowse link
G C5AR1 complement C5a receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:53,097,162...53,111,563
Ensembl chr 6:53,097,164...53,117,020
JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:161,320,627...161,556,539
Ensembl chr 1:161,321,273...161,556,537
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 IEA Ensembl GO_REF:0000107 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,875...57,506,247
JBrowse link
G FLT4 fms related receptor tyrosine kinase 4 IEA Ensembl GO_REF:0000107 NCBI chr 2:78,076,008...78,115,137
Ensembl chr 2:78,076,080...78,115,137
JBrowse link
G GATA4 GATA binding protein 4 ISO (MGI:MGI:3763665|PMID:17975667) BHF-UCL PMID:17975667 MGI:MGI:3763665 NCBI chr14:14,858,470...14,938,156
Ensembl chr14:14,858,159...14,939,941
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HPSE heparanase IEA Ensembl GO_REF:0000107 NCBI chr 8:135,082,199...135,120,887
Ensembl chr 8:135,081,151...135,120,889
JBrowse link
G IL1A interleukin 1 alpha IEA Ensembl GO_REF:0000107 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,119
JBrowse link
G IL6 interleukin 6 IEA Ensembl GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G ISL1 ISL LIM homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907
JBrowse link
G LOC100625479 cytochrome P450 1B1 IEA Ensembl GO_REF:0000107 NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,206,750
JBrowse link
G LOC100737180 C-X-C motif chemokine 17-like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:50,037,606...50,063,561 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO (PMID:12958148)
(MGI:MGI:2652930|PMID:12598651)
BHF-UCL PMID:12598651, PMID:12958148 MGI:MGI:2652930
G LOC110260995 C-X-C motif chemokine 17-like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:50,167,452...50,184,186 JBrowse link
G NODAL nodal growth differentiation factor IEA Ensembl GO_REF:0000107 NCBI chr14:73,350,358...73,357,064
Ensembl chr14:73,349,965...73,360,618
JBrowse link
G NOX1 NADPH oxidase 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,666...82,586,532
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G RORA RAR related orphan receptor A IEA Ensembl GO_REF:0000107 NCBI chr 1:110,719,004...111,482,807
Ensembl chr 1:110,719,190...111,477,703
JBrowse link
G SULF1 sulfatase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:65,595,947...65,778,889
Ensembl chr 4:65,595,949...65,778,884
JBrowse link
G SULF2 sulfatase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:49,663,721...49,805,118
Ensembl chr17:49,663,731...49,804,577
JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chr 6:111,407,632...111,422,169
Ensembl chr 6:111,400,794...111,422,042
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO (MGI:MGI:3840068|PMID:14566334) BHF-UCL PMID:14566334 MGI:MGI:3840068 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCR2 C-C motif chemokine receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G IL6 interleukin 6 ISO (PMID:8557680) BHF-UCL PMID:8557680 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G NDRG2 NDRG family member 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:78,111,736...78,121,216
Ensembl chr 7:78,066,978...78,121,233
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    multicellular organismal process 8037
      cytokine production 714
        vascular endothelial growth factor production 41
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 28
          regulation of vascular endothelial growth factor production + 35
Path 2
Term Annotations click to browse term
  biological_process 16545
    metabolic process 10584
      organic substance metabolic process 10031
        macromolecule metabolic process 8715
          gene expression 5333
            cytokine production 714
              vascular endothelial growth factor production 41
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 28
                regulation of vascular endothelial growth factor production + 35
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.