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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 ISO (PMID:24552833) RGD PMID:24552833 NCBI chr14:19,866,278...20,072,896
Ensembl chr14:19,866,408...20,070,994
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21724588)
Ensembl
UniProt
RGD
PMID:21724588 GO_REF:0000024, GO_REF:0000107 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
(PMID:12958148)
GO_REF:0000107
RGD
Ensembl
PMID:12958148 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Il1b interleukin 1 beta ISO
IEA
ISS
(PMID:12794819)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12794819 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 ISO
ISS
(PMID:12794819)
GO_REF:0000024
RGD
UniProt
PMID:12794819 GO_REF:0000024 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor ISO
ISS
(PMID:12794819)
GO_REF:0000024
RGD
UniProt
PMID:12794819 GO_REF:0000024 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G LOC103694380 tumor necrosis factor-like ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr20:4,855,792...4,858,447
Ensembl chr20:4,855,829...4,858,447
JBrowse link
G Tnf tumor necrosis factor ISO
ISS
(PMID:12794819)
GO_REF:0000024
RGD
UniProt
PMID:12794819 GO_REF:0000024 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 Fms related receptor tyrosine kinase 1 IDA RGD PMID:23804076 RGD:10402115 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Nutf2 nuclear transport factor 2 IMP RGD PMID:19404486 RGD:9831377 NCBI chr19:37,830,917...37,852,192
Ensembl chr19:37,830,917...37,852,189
JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO
ISS
(PMID:24940000)
GO_REF:0000024
RGD
UniProt
PMID:24940000 GO_REF:0000024 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor ISO
IEA
MGI:MGI:3773754 (MGI:MGI:3806198|PMID:18559975)
GO_REF:0000107
RGD
Ensembl
PMID:18559975 GO_REF:0000107, MGI:MGI:3806198 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO
IEA
(PMID:8756616)
GO_REF:0000107
RGD
Ensembl
PMID:8756616 GO_REF:0000107 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf4 activating transcription factor 4 ISO (PMID:22915762) RGD PMID:22915762 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Brca1 BRCA1, DNA repair associated ISO
IEA
(PMID:23415688)
GO_REF:0000107
RGD
Ensembl
PMID:23415688 GO_REF:0000107 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bsg basigin (Ok blood group) ISO
ISS
(PMID:15833850), (PMID:19837976)
GO_REF:0000024
RGD
UniProt
PMID:15833850, PMID:19837976 GO_REF:0000024 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G C3 complement C3 ISO
IEA
(PMID:16452172)
GO_REF:0000107
RGD
Ensembl
PMID:16452172 GO_REF:0000107 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C3ar1 complement C3a receptor 1 ISO
IEA
(MGI:MGI:3617287|PMID:16452172)
GO_REF:0000107
RGD
Ensembl
PMID:16452172 GO_REF:0000107, MGI:MGI:3617287 NCBI chr 4:155,681,767...155,691,240
Ensembl chr 4:155,684,029...155,690,869
JBrowse link
G C5 complement C5 IEA
ISO
GO_REF:0000107
(PMID:14566334), (PMID:16452172)
Ensembl
RGD
PMID:14566334, PMID:16452172 GO_REF:0000107 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G C5ar1 complement C5a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) RGD PMID:16452172 MGI:MGI:3617287 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 ISO
IEA
(PMID:24552833)
GO_REF:0000107
RGD
Ensembl
PMID:24552833 GO_REF:0000107 NCBI chr18:61,758,754...62,013,194
Ensembl chr18:61,759,289...61,788,863
JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 ISO
IBA
ISS
(PMID:23115081)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23115081, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:82,267,381...82,279,145
Ensembl chr 1:82,267,381...82,279,145
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5492227|PMID:23568032)
Ensembl
UniProt
RGD
PMID:23568032 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5492227 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (PMID:22915762)
(MGI:MGI:5607215|PMID:22915762)
RGD PMID:22915762 MGI:MGI:5607215 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 IEA
ISO
GO_REF:0000107
(PMID:19779139)
Ensembl
RGD
PMID:19779139 GO_REF:0000107 NCBI chr10:35,078,782...35,120,296
Ensembl chr10:35,078,726...35,121,599
JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:MGI:3763665|PMID:17975667) RGD PMID:17975667 MGI:MGI:3763665 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEA
ISO
ISS
GO_REF:0000107
(PMID:18658046), (PMID:8756616)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:8756616, PMID:18658046 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hpse heparanase IEA
ISO
GO_REF:0000107
(PMID:16452201)
Ensembl
RGD
PMID:16452201 GO_REF:0000107 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224
JBrowse link
G Il1a interleukin 1 alpha ISO
IEA
(MGI:MGI:2652930|PMID:12598651)
GO_REF:0000107
RGD
Ensembl
PMID:12598651 GO_REF:0000107, MGI:MGI:2652930 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta ISO
IEA
(PMID:12958148)
GO_REF:0000107
(MGI:MGI:2652930|PMID:12598651)
RGD
Ensembl
PMID:12598651, PMID:12958148 GO_REF:0000107, MGI:MGI:2652930 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 ISO (PMID:28433754) RGD PMID:28433754 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:MGI:5437583|PMID:22727192) RGD PMID:22727192 MGI:MGI:5437583 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:21116837) RGD PMID:21116837 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Nox1 NADPH oxidase 1 ISO
IEA
(PMID:11805326)
GO_REF:0000107
RGD
Ensembl
PMID:11805326 GO_REF:0000107 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rora RAR-related orphan receptor A ISO (PMID:18658046) RGD PMID:18658046 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Sulf1 sulfatase 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
UniProtKB:Q8CFG0 (MGI:MGI:5306737|PMID:21719793)
Ensembl
RGD
PMID:21719793, PMID:21873635 GO_REF:0000107, MGI:MGI:5306737, RGD:13792537 NCBI chr 5:5,999,520...6,186,901
Ensembl chr 5:5,999,475...6,186,329
JBrowse link
G Sulf2 sulfatase 2 ISO
IBA
UniProtKB:Q8K007 (MGI:MGI:5306737|PMID:21719793)
PMID:21873635
RGD PMID:21719793, PMID:21873635 MGI:MGI:5306737, RGD:13792537 NCBI chr 3:162,791,349...162,872,984
Ensembl chr 3:162,791,355...162,872,831
JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 IMP RGD PMID:22449442 RGD:8695996 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO (MGI:MGI:3840068|PMID:14566334) RGD PMID:14566334 MGI:MGI:3840068 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO
ISS
(MGI:MGI:3840068|PMID:14566334)
GO_REF:0000024
RGD
BHF-UCL
PMID:14566334 GO_REF:0000024, MGI:MGI:3840068
G Il6 interleukin 6 ISO (PMID:8557680) RGD PMID:8557680 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ndrg2 NDRG family member 2 ISO
IEA
(MGI:MGI:4835375|PMID:19815093)
GO_REF:0000107
RGD
Ensembl
PMID:19815093 GO_REF:0000107, MGI:MGI:4835375 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    multicellular organismal process 9046
      cytokine production 764
        vascular endothelial growth factor production 39
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 27
          regulation of vascular endothelial growth factor production + 34
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          gene expression 6304
            cytokine production 764
              vascular endothelial growth factor production 39
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 27
                regulation of vascular endothelial growth factor production + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.