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ONTOLOGY REPORT - ANNOTATIONS


Term:vascular endothelial growth factor production
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Accession:GO:0010573 term browser browse the term
Definition:The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms:exact_synonym: VEGF production


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vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts3 ADAM metallopeptidase with thrombospondin type 1 motif 3 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chrNW_004936598:2,680,623...2,901,308 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 ISO (PMID:21724588) UniProtKB PMID:21724588 NCBI chrNW_004936475:9,653,233...9,683,258 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (PMID:12958148) BHF-UCL PMID:12958148 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G Il1b interleukin 1 beta ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Il6r interleukin 6 receptor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004936580:4,055,438...4,081,876 JBrowse link
G Tnf tumor necrosis factor ISO (PMID:12794819) UniProt PMID:12794819 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
negative regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23804076 RGD:10402115 NCBI chrNW_004936472:23,442,946...23,617,523 JBrowse link
G Nutf2 nuclear transport factor 2 ISO RGD PMID:19404486 RGD:9831377 NCBI chrNW_004936475:18,214,593...18,232,406 JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO (PMID:24940000) UniProtKB PMID:24940000 NCBI chrNW_004936704:747,109...766,981 JBrowse link
positive regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO (MGI:MGI:3806198|PMID:18559975) MGI PMID:18559975 MGI:MGI:3806198 NCBI chrNW_004936821:583,463...608,189 JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO (PMID:8756616) BHF-UCL PMID:8756616 NCBI chrNW_004936580:1,038,420...1,093,319 JBrowse link
G Atf4 activating transcription factor 4 ISO (PMID:22915762) ParkinsonsUK-UCL PMID:22915762 NCBI chrNW_004936492:2,114,478...2,115,969 JBrowse link
G Brca1 BRCA1 DNA repair associated ISO (PMID:23415688) BHF-UCL PMID:23415688 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Bsg basigin (Ok blood group) ISO (PMID:19837976)
(PMID:15833850)
UniProt PMID:15833850, PMID:19837976 NCBI chrNW_004936588:181,688...189,795 JBrowse link
G C3 complement C3 ISO (PMID:16452172) BHF-UCL PMID:16452172 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C3ar1 complement C3a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chrNW_004936892:347,547...355,143 JBrowse link
G C5ar1 complement C5a receptor 1 ISO (MGI:MGI:3617287|PMID:16452172) BHF-UCL PMID:16452172 MGI:MGI:3617287 NCBI chrNW_004936664:1,026,216...1,033,438 JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 ISO (PMID:24552833) BHF-UCL PMID:24552833 NCBI chrNW_004936497:5,290,068...5,321,656 JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 ISO (PMID:23115081) UniProtKB PMID:23115081 NCBI chrNW_004936706:62,417...119,278 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:5607215|PMID:22915762)
(PMID:22915762)
ParkinsonsUK-UCL PMID:22915762 MGI:MGI:5607215 NCBI chrNW_004936712:413,602...454,443 JBrowse link
G Flt4 fms related receptor tyrosine kinase 4 ISO (PMID:19779139) UniProtKB PMID:19779139 NCBI chrNW_004936739:240,572...281,925 JBrowse link
G Gata4 GATA binding protein 4 ISO (MGI:MGI:3763665|PMID:17975667) BHF-UCL PMID:17975667 MGI:MGI:3763665 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (PMID:18658046)
(PMID:8756616)
UniProtKB
BHF-UCL
PMID:8756616, PMID:18658046 NCBI chrNW_004936495:5,770,988...5,816,157 JBrowse link
G Hpse heparanase ISO (PMID:16452201) UniProtKB PMID:16452201 NCBI chrNW_004936738:1,308,350...1,341,421 JBrowse link
G Il1a interleukin 1 alpha ISO (MGI:MGI:2652930|PMID:12598651) BHF-UCL PMID:12598651 MGI:MGI:2652930 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta ISO (MGI:MGI:2652930|PMID:12598651)
(PMID:12958148)
BHF-UCL PMID:12598651, PMID:12958148 MGI:MGI:2652930 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Isl1 ISL LIM homeobox 1 ISO (MGI:MGI:5437583|PMID:22727192) BHF-UCL PMID:22727192 MGI:MGI:5437583 NCBI chrNW_004936480:15,805,259...15,817,854 JBrowse link
G LOC101959685 complement C5 ISO (PMID:14566334), (PMID:16452172) BHF-UCL PMID:14566334, PMID:16452172 NCBI chrNW_004936487:9,391,774...9,474,168 JBrowse link
G LOC101970101 cytochrome P450 1B1 ISO (MGI:MGI:5492227|PMID:23568032) UniProtKB PMID:23568032 MGI:MGI:5492227 NCBI chrNW_004936663:345,021...355,188 JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:21116837) BHF-UCL PMID:21116837 NCBI chrNW_004936521:8,171,146...8,178,802 JBrowse link
G Nox1 NADPH oxidase 1 ISO (PMID:11805326) BHF-UCL PMID:11805326 NCBI chrNW_004936584:6,023,960...6,040,041 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rora RAR related orphan receptor A ISO (PMID:18658046) UniProtKB PMID:18658046 NCBI chrNW_004936471:21,402,056...21,567,908 JBrowse link
G Sulf1 sulfatase 1 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chrNW_004936496:4,755,806...4,931,964 JBrowse link
G Sulf2 sulfatase 2 ISO (MGI:MGI:5306737|PMID:21719793) UniProtKB PMID:21719793 MGI:MGI:5306737 NCBI chrNW_004936514:5,819,375...5,899,324 JBrowse link
regulation of vascular endothelial growth factor production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp4 aquaporin 4 ISO RGD PMID:22449442 RGD:8695996 NCBI chrNW_004936550:5,931,201...5,943,999 JBrowse link
G Ndrg2 NDRG family member 2 ISO (MGI:MGI:4835375|PMID:19815093) MGI PMID:19815093 MGI:MGI:4835375 NCBI chrNW_004936880:219,131...227,856 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11998
    multicellular organismal process 6221
      cytokine production 647
        vascular endothelial growth factor production 35
          negative regulation of vascular endothelial growth factor production 3
          positive regulation of vascular endothelial growth factor production 26
          regulation of vascular endothelial growth factor production + 31
Path 2
Term Annotations click to browse term
  biological_process 11998
    metabolic process 7668
      organic substance metabolic process 7372
        macromolecule metabolic process 6390
          gene expression 3957
            cytokine production 647
              vascular endothelial growth factor production 35
                negative regulation of vascular endothelial growth factor production 3
                positive regulation of vascular endothelial growth factor production 26
                regulation of vascular endothelial growth factor production + 31
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.