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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of epithelial to mesenchymal transition
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Accession:GO:0010717 term browser browse the term
Definition:Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


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regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clasp1 cytoplasmic linker associated protein 1 ISO (PMID:23940118) RGD PMID:23940118 NCBI chr13:34,365,038...34,584,651
Ensembl chr13:34,365,147...34,584,651
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 ISO
IEA
(PMID:23940118)
GO_REF:0000107
RGD
Ensembl
PMID:23940118 GO_REF:0000107 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Dag1 dystroglycan 1 ISO (PMID:23940118) RGD PMID:23940118 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 ISS
ISO
GO_REF:0000024
(MGI:5438719|PMID:22768269)
UniProt
RGD
PMID:22768269 GO_REF:0000024, MGI:5438719 NCBI chr 3:113,400,395...113,405,869
Ensembl chr 3:113,401,734...113,405,829
JBrowse link
G Epha3 Eph receptor A3 ISS
ISO
GO_REF:0000024
(MGI:3703403|PMID:17046737)
UniProt
RGD
PMID:17046737 GO_REF:0000024, MGI:3703403 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (PMID:16816361) RGD PMID:16816361 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G LOC103690035 TGF-beta receptor type-1-like ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:64,565,358...64,585,219
Ensembl chr 5:64,566,804...64,584,309
JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 ISO
ISS
(PMID:25728771)
GO_REF:0000024
RGD
UniProt
PMID:25728771 GO_REF:0000024 NCBI chr10:109,720,144...109,727,595
Ensembl chr10:109,720,144...109,722,195
JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 IEA
ISO
GO_REF:0000107
(PMID:23940118)
Ensembl
RGD
PMID:23940118 GO_REF:0000107 NCBI chr 8:48,997,189...49,045,176
Ensembl chr 8:48,997,184...49,045,154
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 ISO (PMID:23940118) RGD PMID:23940118 NCBI chr11:60,042,879...60,051,229
Ensembl chr11:57,265,732...57,481,589
JBrowse link
G Pofut2 protein O-fucosyltransferase 2 ISO MGI:3604508|MGI:4127173 (MGI:4838381|PMID:20637190) RGD PMID:20637190 MGI:4838381 NCBI chr20:12,117,811...12,128,747
Ensembl chr20:12,117,811...12,128,747
JBrowse link
G Smad7 SMAD family member 7 ISO
IEA
(PMID:24887517)
GO_REF:0000107
RGD
Ensembl
PMID:24887517 GO_REF:0000107 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 ISO (PMID:20826792) RGD PMID:20826792 NCBI chr11:29,931,083...30,061,173
Ensembl chr11:29,933,163...30,051,103
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 ISO
IEA
ISS
(PMID:17072303)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17072303 GO_REF:0000024, GO_REF:0000107 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO (PMID:17072303) RGD PMID:17072303 NCBI chr 1:276,686,911...276,730,517
Ensembl chr 1:276,659,542...276,730,514
Ensembl chr 1:276,659,542...276,730,514
JBrowse link
negative regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 ISO (PMID:23776679) RGD PMID:23776679 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Dab2ip DAB2 interacting protein IEA
ISO
ISS
GO_REF:0000107
(PMID:20080667), (PMID:20154697)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:20080667, PMID:20154697 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 ISO MGI:5515616 (MGI:5503293|PMID:23580654) RGD PMID:23580654 MGI:5503293 NCBI chr 1:78,800,754...78,812,483
Ensembl chr 1:78,800,754...78,812,483
JBrowse link
G Efna1 ephrin A1 ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Foxa1 forkhead box A1 ISO
IEA
(PMID:20160041)
GO_REF:0000107
RGD
Ensembl
PMID:20160041 GO_REF:0000107 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxa2 forkhead box A2 ISO
IEA
(PMID:20160041)
GO_REF:0000107
RGD
Ensembl
PMID:20160041 GO_REF:0000107 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Gata3 GATA binding protein 3 ISO (PMID:26451614) RGD PMID:26451614 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Hpn hepsin IEA
IBA
ISS
ISO
GO_REF:0000107
PMID:21873635
GO_REF:0000024
(PMID:19843851)
Ensembl
UniProt
RGD
PMID:19843851, PMID:21873635 GO_REF:0000024, GO_REF:0000107, RGD:13792537 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Il17rd interleukin 17 receptor D ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 ISO (PMID:24627487) RGD PMID:24627487 NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO (PMID:19443654) RGD PMID:19443654 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Nkx2-1 NK2 homeobox 1 IEA
ISO
GO_REF:0000107
(PMID:19293183)
Ensembl
RGD
PMID:19293183 GO_REF:0000107 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Ovol2 ovo-like zinc finger 2 ISO (MGI:5574425|PMID:24735879), (MGI:6284898|PMID:28455959) RGD PMID:24735879, PMID:28455959 MGI:5574425, MGI:6284898 NCBI chr 3:138,433,990...138,464,511
Ensembl chr 3:138,433,990...138,462,063
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 ISO (PMID:23687415) RGD PMID:23687415 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO (PMID:20080667) RGD PMID:20080667 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Pten phosphatase and tensin homolog ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 ISO (PMID:23983127)
(MGI:5529200|PMID:23983127)
RGD PMID:23983127 MGI:5529200 NCBI chr 1:226,543,671...226,572,414
Ensembl chr 1:226,547,531...226,572,349
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO
GO_REF:0000107
(PMID:19095296)
Ensembl
RGD
PMID:19095296 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO (PMID:19095296) RGD PMID:19095296 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 3:108,795,337...108,861,650
Ensembl chr 3:108,795,235...108,857,556
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 ISS
ISO
IEA
GO_REF:0000024
(MGI:6414689|PMID:25576668)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25576668 GO_REF:0000024, GO_REF:0000107, MGI:6414689 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456
JBrowse link
G Spred3 sprouty-related, EVH1 domain containing 3 ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 1:88,101,213...88,112,719
Ensembl chr 1:88,103,719...88,112,683
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO (MGI:6414689|PMID:25576668) RGD PMID:25576668 MGI:6414689 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Strap serine/threonine kinase receptor associated protein ISO (PMID:23687415) RGD PMID:23687415 NCBI chr 4:171,730,629...171,744,877
Ensembl chr 4:171,730,635...171,745,377
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:3762085|PMID:17823118) RGD PMID:17823118 MGI:3762085 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Trim62 tripartite motif-containing 62 ISO MGI:5538538 (MGI:5585203|PMID:24890125) RGD PMID:24890125 MGI:5585203 NCBI chr 5:147,068,725...147,099,024
Ensembl chr 5:147,069,616...147,095,242
JBrowse link
G Tsc2 TSC complex subunit 2 IMP RGD PMID:20813961 RGD:11568680 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link
G Usf3 upstream transcription factor family member 3 ISO
IBA
(PMID:28011713)
PMID:21873635
RGD PMID:28011713, PMID:21873635 RGD:13792537 NCBI chr11:61,427,140...61,499,668
Ensembl chr11:61,432,064...61,499,557
JBrowse link
G Vasn vasorin ISO (PMID:21170088) RGD PMID:21170088 NCBI chr10:11,121,041...11,131,548
Ensembl chr10:11,121,041...11,131,548
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Znf750 zinc finger protein 750 ISO (PMID:32042337) RGD PMID:32042337 NCBI chr10:110,698,581...110,701,222
Ensembl chr10:110,698,891...110,701,137
JBrowse link
negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nog noggin IEA
ISO
GO_REF:0000107
(MGI:3783944|PMID:17218603)
Ensembl
RGD
PMID:17218603 GO_REF:0000107, MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
negative regulation of neural crest formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fuz fuzzy planar cell polarity protein ISS
ISO
GO_REF:0000024
(MGI:5498583|PMID:23806618)
UniProt
RGD
PMID:23806618 GO_REF:0000024, MGI:5498583 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
positive regulation of cardiac epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jag1 jagged canonical Notch ligand 1 IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Notch1 notch receptor 1 IGI PMID:20951801 BHF-UCL PMID:20951801 RGD:13601997 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
positive regulation of epithelial to mesenchymal transition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor IMP RGD PMID:21743278 RGD:7243870 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Alx1 ALX homeobox 1 ISO
ISS
(PMID:23288509)
GO_REF:0000024
RGD
UniProt
PMID:23288509 GO_REF:0000024 NCBI chr 7:44,751,865...44,771,458
Ensembl chr 7:44,751,873...44,771,458
JBrowse link
G Axin2 axin 2 ISO
IEA
(PMID:17072303)
GO_REF:0000107
RGD
Ensembl
PMID:17072303 GO_REF:0000107 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO (PMID:19328798) RGD PMID:19328798 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bcl9l BCL9 like ISO (PMID:19328798) RGD PMID:19328798 NCBI chr 8:48,805,684...48,835,794
Ensembl chr 8:48,805,684...48,834,312
JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO
IEA
(PMID:20890042)
MGI:3583785 (MGI:3611958|PMID:16314491)
GO_REF:0000107
RGD
Ensembl
PMID:16314491, PMID:20890042 GO_REF:0000107, MGI:3611958 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
UniProtKB:P23359 (MGI:5502250|PMID:23863481)
Ensembl
RGD
PMID:23863481 GO_REF:0000107, MGI:5502250 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO UniProtKB:P21275 (MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:5502250 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO (PMID:20018240) RGD PMID:20018240 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crb2 crumbs cell polarity complex component 2 ISS
ISO
GO_REF:0000024
(MGI:5296388|PMID:22072575), (MGI:5823085|PMID:27870829)
UniProt
RGD
PMID:22072575, PMID:27870829 GO_REF:0000024, MGI:5296388, MGI:5823085 NCBI chr 3:22,037,812...22,061,247
Ensembl chr 3:22,038,357...22,058,871
JBrowse link
G Ctnnb1 catenin beta 1 ISO UniProtKB:Q9NX18 (PMID:23983127) RGD PMID:23983127 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Dab2 DAB adaptor protein 2 IEA
ISO
GO_REF:0000107
(MGI:5442513|PMID:15734730)
Ensembl
RGD
PMID:15734730 GO_REF:0000107, MGI:5442513 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fermt2 fermitin family member 2 ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Foxc1 forkhead box C1 ISO (PMID:22991501) RGD PMID:22991501 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) ISO (PMID:21750175)
(MGI:5545971|PMID:21750175)
RGD PMID:21750175 MGI:5545971 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Glipr2 GLI pathogenesis-related 2 ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:59,415,415...59,446,732
Ensembl chr 5:59,416,076...59,446,647
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:19553350 RGD:9590229 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Il1b interleukin 1 beta IEA
ISO
GO_REF:0000107
(PMID:25204733)
Ensembl
RGD
PMID:25204733 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 ISO (PMID:25916550) RGD PMID:25916550 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Isl1 ISL LIM homeobox 1 IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 IEA
ISO
GO_REF:0000107
(PMID:20018240)
Ensembl
RGD
PMID:20018240 GO_REF:0000107 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Loxl2 lysyl oxidase-like 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:24239292)
Ensembl
UniProt
RGD
PMID:24239292 GO_REF:0000024, GO_REF:0000107 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Mdk midkine ISS
ISO
GO_REF:0000024
(PMID:18469519)
UniProt
RGD
PMID:18469519 GO_REF:0000024 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO (PMID:27919618) RGD PMID:27919618 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Myocd myocardin IMP PMID:23270756 BHF-UCL PMID:23270756 RGD:13210526 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Olfm1 olfactomedin 1 ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Pdpn podoplanin ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:17046996), (PMID:21376833)
UniProt
RGD
PMID:17046996, PMID:21376833, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:161,947,137...161,981,441
Ensembl chr 5:161,947,137...161,981,441
JBrowse link
G Rgcc regulator of cell cycle ISO (PMID:19158077), (PMID:21307346) RGD PMID:19158077, PMID:21307346 NCBI chr15:61,551,861...61,564,695
Ensembl chr15:61,551,861...61,564,695
JBrowse link
G Sdcbp syndecan binding protein ISO
ISS
(PMID:25893292)
GO_REF:0000024
RGD
UniProt
PMID:25893292 GO_REF:0000024 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485
JBrowse link
G Serpinb3 serpin family B member 3 ISO (PMID:20527027) RGD PMID:20527027 NCBI chr13:27,186,701...27,193,211
Ensembl chr13:27,187,130...27,192,592
JBrowse link
G Smad2 SMAD family member 2 ISO (MGI:2683382|PMID:14691138) RGD PMID:14691138 MGI:2683382 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 ISO (PMID:18505915), (PMID:21307346) RGD PMID:18505915, PMID:21307346 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad4 SMAD family member 4 IEA
ISO
GO_REF:0000107
(MGI:2683382|PMID:14691138)
Ensembl
RGD
PMID:14691138 GO_REF:0000107, MGI:2683382 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Snai1 snail family transcriptional repressor 1 ISO (PMID:20018240), (PMID:23288509)
(MGI:4837019|PMID:20890042), (MGI:5548026|PMID:24239292)
RGD PMID:20018240, PMID:20890042, PMID:23288509, PMID:24239292 MGI:4837019, MGI:5548026 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISS
ISO
GO_REF:0000024
(MGI:3821807|PMID:18794329)
(PMID:17999987), (PMID:18505915)
UniProt
RGD
PMID:17999987, PMID:18505915, PMID:18794329 GO_REF:0000024, MGI:3821807 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISS
ISO
GO_REF:0000024
(PMID:17999987), (PMID:18505915)
AgBase
RGD
PMID:17999987, PMID:18505915 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 ISS
ISO
GO_REF:0000024
(MGI:2683382|PMID:14691138)
(PMID:18505915), (PMID:18718461)
AgBase
RGD
PMID:14691138, PMID:18505915, PMID:18718461 GO_REF:0000024, MGI:2683382 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO UniProtKB:P10600 (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (PMID:26459119) RGD PMID:26459119 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:18297062)
(MGI:4838344|PMID:20804746), (MGI:5284765|PMID:18297062), (MGI:5284780|PMID:17332324)
RGD PMID:17332324, PMID:18297062, PMID:20804746 MGI:4838344, MGI:5284765, MGI:5284780 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 ISO (PMID:18227151) RGD PMID:18227151 NCBI chr 2:147,577,149...147,693,033
Ensembl chr 2:147,577,089...147,693,082
JBrowse link
G Zfp703 zinc finger protein 703 ISO (MGI:4940410|PMID:21317240) RGD PMID:21317240 MGI:4940410 NCBI chr16:69,237,857...69,242,028
Ensembl chr16:69,237,857...69,242,028
JBrowse link
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 IEA
ISO
GO_REF:0000107
(MGI:3610266|PMID:16140292)
Ensembl
RGD
PMID:16140292 GO_REF:0000107, MGI:3610266 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Eng endoglin ISO (MGI:4368063|PMID:19703439) RGD PMID:19703439 MGI:4368063 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO (MGI:3820811|PMID:18718461) RGD PMID:18718461 MGI:3820811 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:3801267 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 NOT ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 NOT ISO (MGI:3830400|PMID:19161227) RGD PMID:19161227 MGI:3830400 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
regulation of neural crest cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A NOT ISO (MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    regulation of biological process 13071
      regulation of cellular process 12556
        regulation of cell differentiation 1684
          regulation of epithelial to mesenchymal transition 97
            negative regulation of epithelial to mesenchymal transition + 35
            positive regulation of epithelial to mesenchymal transition + 49
            regulation of cardiac epithelial to mesenchymal transition + 11
            regulation of neural crest formation + 2
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              mesenchyme development 293
                mesenchymal cell differentiation 233
                  epithelial to mesenchymal transition 152
                    regulation of epithelial to mesenchymal transition 97
                      negative regulation of epithelial to mesenchymal transition + 35
                      positive regulation of epithelial to mesenchymal transition + 49
                      regulation of cardiac epithelial to mesenchymal transition + 11
                      regulation of neural crest formation + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.