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Term:negative regulation of cGMP-mediated signaling
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Accession:GO:0010754 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
Synonyms:exact_synonym: negative regulation of cGMP-mediated signalling

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negative regulation of cGMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mtnr1b melatonin receptor 1B JBrowse link 8 14,359,270 14,373,894 RGD:9588673
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:1624291
G Pdzd3 PDZ domain containing 3 JBrowse link 8 48,577,905 48,582,353 RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7552
      negative regulation of signaling 1395
        negative regulation of signal transduction 1232
          negative regulation of intracellular signal transduction 546
            negative regulation of cGMP-mediated signaling 9
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13635
      regulation of biological process 12958
        regulation of cellular process 12441
          signal transduction 6967
            intracellular signal transduction 2597
              second-messenger-mediated signaling 481
                cyclic-nucleotide-mediated signaling 236
                  cGMP-mediated signaling 38
                    regulation of cGMP-mediated signaling 20
                      negative regulation of cGMP-mediated signaling 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.