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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of centrosome duplication
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Accession:GO:0010826 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.


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negative regulation of centrosome duplication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnf cyclin F JBrowse link 10 13,594,687 13,619,935 RGD:1624291
RGD:1600115
G Npm1 nucleophosmin 1 JBrowse link 10 18,080,949 18,091,062 RGD:1624291
G Nubp1 nucleotide binding protein 1 JBrowse link 10 5,333,378 5,343,949 RGD:1624291
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554306
RGD:1624291
RGD:1600115
negative regulation of centriole elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chmp2a charged multivesicular body protein 2A JBrowse link 1 65,540,808 65,543,708 RGD:1624291
negative regulation of centriole replication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 JBrowse link 5 86,387,238 86,554,108 RGD:1600115
RGD:1624291
G Kat2a lysine acetyltransferase 2A JBrowse link 10 88,611,586 88,619,558 RGD:1624291
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Mdm1 Mdm1 nuclear protein JBrowse link 7 61,165,652 61,200,865 RGD:1600115
RGD:1624291
G Rbm14 RNA binding motif protein 14 JBrowse link 1 220,048,740 220,067,124 RGD:1624291
G Trim37 tripartite motif-containing 37 JBrowse link 10 74,436,165 74,568,636 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      cell cycle process 1187
        centrosome duplication 72
          negative regulation of centrosome duplication 11
            negative regulation of centriole replication + 7
Path 2
Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      cellular component organization 6221
        organelle organization 3831
          cytoskeleton organization 1398
            microtubule cytoskeleton organization 607
              microtubule organizing center organization 141
                centrosome cycle 130
                  regulation of centrosome cycle 63
                    regulation of centrosome duplication 47
                      negative regulation of centrosome duplication 11
                        negative regulation of centriole replication + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.