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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of steroid biosynthetic process
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Accession:GO:0010894 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


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negative regulation of steroid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:2316921
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:1624291
G Insig2 insulin induced gene 2 JBrowse link 13 37,264,818 37,292,718 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1624291
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of androgen biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Malrd1 MAM and LDL receptor class A domain containing 1 JBrowse link 17 82,430,836 83,156,696 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1624291
RGD:1600115
RGD:10059686
G Erlin1 ER lipid raft associated 1 JBrowse link 1 263,810,439 263,845,762 RGD:1624291
G Erlin2 ER lipid raft associated 2 JBrowse link 16 69,179,005 69,195,452 RGD:1624291
G Idi2 isopentenyl-diphosphate delta isomerase 2 JBrowse link 17 63,107,152 63,107,469 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1624291
RGD:1600115
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:1624291
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkkl1 dickkopf like acrosomal protein 1 JBrowse link 1 101,205,426 101,210,675 RGD:1624291
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      negative regulation of metabolic process 3076
        negative regulation of lipid metabolic process 102
          negative regulation of steroid metabolic process 25
            negative regulation of steroid biosynthetic process 24
              negative regulation of androgen biosynthetic process 1
              negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
              negative regulation of bile acid biosynthetic process 3
              negative regulation of estrogen biosynthetic process 0
              negative regulation of helvolic acid biosynthetic process 0
              negative regulation of progesterone biosynthetic process + 0
              negative regulation of steroid hormone biosynthetic process + 6
              negative regulation of sterol biosynthetic process + 5
              negative regulation of testosterone biosynthetic process 2
              negative regulation of vitamin D biosynthetic process + 5
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13446
      regulation of biological process 12748
        regulation of metabolic process 6582
          regulation of primary metabolic process 5838
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 110
                negative regulation of steroid metabolic process 25
                  negative regulation of steroid biosynthetic process 24
                    negative regulation of androgen biosynthetic process 1
                    negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
                    negative regulation of bile acid biosynthetic process 3
                    negative regulation of estrogen biosynthetic process 0
                    negative regulation of helvolic acid biosynthetic process 0
                    negative regulation of progesterone biosynthetic process + 0
                    negative regulation of steroid hormone biosynthetic process + 6
                    negative regulation of sterol biosynthetic process + 5
                    negative regulation of testosterone biosynthetic process 2
                    negative regulation of vitamin D biosynthetic process + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.