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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of necrotic cell death
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Accession:GO:0010940 term browser browse the term
Definition:Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.


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positive regulation of necrotic cell death term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bnip3 BCL2 interacting protein 3 IMP RGD PMID:25489073 RGD:11561978 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Hebp2 heme binding protein 2 ISO (PMID:17098234) RGD PMID:17098234 NCBI chr 1:13,713,152...13,719,970
Ensembl chr 1:13,714,440...13,719,829
JBrowse link
G Il17a interleukin 17A IDA RGD PMID:22990529 RGD:9068935 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II IMP RGD PMID:19306371 RGD:13506652 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt3 metallothionein 3 ISS
ISO
GO_REF:0000024
(PMID:15129022), (PMID:16387743)
UniProt
RGD
PMID:15129022, PMID:16387743 GO_REF:0000024 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 ISO (PMID:20550618) RGD PMID:20550618 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 ISO (MGI:5796070|PMID:26559832) RGD PMID:26559832 MGI:5796070 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G Slc6a13 solute carrier family 6 member 13 ISO
IEA
(PMID:24842606)
GO_REF:0000107
RGD
Ensembl
PMID:24842606 GO_REF:0000107 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155
JBrowse link
G Slc6a6 solute carrier family 6 member 6 ISO (PMID:24842606) RGD PMID:24842606 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Tspo translocator protein IMP RGD PMID:15284300 RGD:2317153 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
positive regulation of necroptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gzmb granzyme B IMP RGD PMID:19895873 RGD:2325193 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 IMP
ISO
(PMID:22028622), (PMID:22274400), (PMID:22817896) RGD PMID:22028622, PMID:22274400, PMID:22817896, PMID:22372834 RGD:7777172 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 ISO
ISS
(PMID:22265414), (PMID:22817896)
(MGI:5315337|PMID:21052097), (MGI:5516181|PMID:22265414), (MGI:5602910|PMID:24813850), (MGI:5602911|PMID:24813849), (MGI:6434626|PMID:32296175), (MGI:6436371|PMID:22423968), (MGI:6436412|PMID:32200799), (MGI:6436434|PMID:27321907)
GO_REF:0000024
RGD
UniProt
PMID:21052097, PMID:22265414, PMID:22423968, PMID:22817896, PMID:24813849, PMID:24813850, PMID:27321907, PMID:32200799, PMID:32296175 GO_REF:0000024, MGI:5315337, MGI:5516181, MGI:5602910, MGI:5602911, MGI:6434626, MGI:6436371, MGI:6436412, MGI:6436434 NCBI chr15:34,470,796...34,479,741
Ensembl chr15:34,470,796...34,479,741
JBrowse link
G Zbp1 Z-DNA binding protein 1 ISO
ISS
(PMID:32200799)
(MGI:5907398|PMID:27819682), (MGI:5907399|PMID:27819681), (MGI:6095612|PMID:29073079), (MGI:6434626|PMID:32296175), (MGI:6436371|PMID:22423968), (MGI:6436393|PMID:30050136), (MGI:6436412|PMID:32200799), (MGI:6436445|PMID:27746097), (MGI:6442612|PMID:27917412)
GO_REF:0000024
RGD
UniProt
PMID:22423968, PMID:27746097, PMID:27819681, PMID:27819682, PMID:27917412, PMID:29073079, PMID:30050136, PMID:32200799, PMID:32296175 GO_REF:0000024, MGI:5907398, MGI:5907399, MGI:6095612, MGI:6434626, MGI:6436371, MGI:6436393, MGI:6436412, MGI:6436445, MGI:6442612 NCBI chr 3:171,276,062...171,292,062
Ensembl chr 3:171,276,062...171,286,537
JBrowse link
positive regulation of programmed necrotic cell death term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 ISO (MGI:6140989|PMID:27258785) RGD PMID:27258785 MGI:6140989 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    cellular process 18802
      positive regulation of cellular process 6141
        positive regulation of cell death 710
          positive regulation of necrotic cell death 13
            positive regulation of programmed necrotic cell death + 5
Path 2
Term Annotations click to browse term
  biological_process 20030
    biological regulation 13774
      regulation of biological process 13076
        regulation of cellular process 12564
          regulation of cell death 1763
            positive regulation of cell death 710
              positive regulation of necrotic cell death 13
                positive regulation of programmed necrotic cell death + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.