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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of endopeptidase activity
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Accession:GO:0010951 term browser browse the term
Definition:Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.


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negative regulation of endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 4 154,309,426 154,359,138 RGD:7411612
G A2ml1 alpha-2-macroglobulin-like 1 JBrowse link 4 161,863,609 161,907,897 RGD:1600115
G AABR07028488.1 RGD:1600115
G AABR07034362.2 RGD:1600115
G AABR07034632.1 RGD:1600115
G AABR07054167.1 RGD:1600115
G AABR07061950.1 RGD:1600115
G AC105815.1 RGD:1600115
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:13792537
G Ahsg alpha-2-HS-glycoprotein JBrowse link 11 81,711,269 81,717,594 RGD:13792537
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Ambp alpha-1-microglobulin/bikunin precursor JBrowse link 5 78,975,690 78,986,021 RGD:1600115
G Andpro androgen regulated protein JBrowse link 3 143,893,005 143,899,609 RGD:1600115
G Anos1 anosmin 1 RGD:1600115
G Aplp2 amyloid beta precursor like protein 2 JBrowse link 8 32,298,526 32,328,821 RGD:1600115
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1600115
G Birc6 baculoviral IAP repeat-containing 6 JBrowse link 6 21,900,763 22,092,484 RGD:1600115
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 16 19,938,781 19,942,353 RGD:1600115
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600115
G C4a complement C4A JBrowse link 20 2,651,599 2,678,183 RGD:1600115
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:1600115
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:1600115
G Cd109 CD109 molecule JBrowse link 8 85,951,420 86,065,411 RGD:1600115
G Col28a1 collagen type XXVIII alpha 1 chain JBrowse link 4 34,048,074 34,198,558 RGD:1600115
G Crb2 crumbs cell polarity complex component 2 JBrowse link 3 22,037,812 22,061,247 RGD:1624291
RGD:1600115
G Crim1 cysteine rich transmembrane BMP regulator 1 JBrowse link 6 788,490 962,663 RGD:1600115
G Cst11 cystatin 11 JBrowse link 3 143,096,056 143,098,780 RGD:1600115
G Cst12 cystatin 12 JBrowse link 3 143,119,697 143,123,557 RGD:1600115
G Cst13 cystatin 13 JBrowse link 3 143,151,398 143,161,491 RGD:1600115
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:1600115
G Cst5 cystatin D JBrowse link 3 144,569,502 144,574,112 RGD:1600115
G Cst6 cystatin E/M JBrowse link 1 220,727,292 220,729,000 RGD:1600115
G Cst8 cystatin 8 JBrowse link 3 143,129,240 143,141,000 RGD:1600115
G Cst9l cystatin 9-like JBrowse link 3 143,172,691 143,175,504 RGD:1600115
G Csta cystatin A JBrowse link 11 67,555,792 67,566,980 RGD:1600115
G Cstb cystatin B JBrowse link 20 10,966,357 10,968,399 RGD:1600115
G Cstl1 cystatin-like 1 JBrowse link 3 143,084,557 143,089,554 RGD:1600115
G Cyss cystatin S JBrowse link 3 144,427,430 144,431,768 RGD:1600115
G Eppin epididymal peptidase inhibitor JBrowse link 3 161,043,761 161,050,550 RGD:1600115
G Fetub fetuin B JBrowse link 11 81,648,890 81,660,472 RGD:1600115
RGD:13792537
RGD:1624291
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1600115
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 4 157,676,336 157,680,322 RGD:1624291
G Hrg histidine-rich glycoprotein JBrowse link 11 81,621,274 81,639,938 RGD:1600115
RGD:13792537
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 JBrowse link 16 7,012,376 7,026,542 RGD:1600115
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 JBrowse link 17 72,160,734 72,197,248 RGD:1600115
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 JBrowse link 16 6,983,779 7,007,288 RGD:1600115
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 JBrowse link 16 6,970,367 6,985,538 RGD:1600115
G Kng1 kininogen 1 JBrowse link 11 81,421,672 81,444,466 RGD:13792537
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:13792537
G Kng2l1 kininogen 2-like 1 RGD:13792537
G LOC100362978 rCG64393-like JBrowse link 11 67,436,286 67,440,612 RGD:1600115
G LOC100909524 protein Z-dependent protease inhibitor-like JBrowse link 6 129,004,249 129,012,705 RGD:13792537
G LOC100909605 serine protease inhibitor A3F-like JBrowse link 6 129,052,476 129,060,050 RGD:13792537
G LOC100910851 serine protease inhibitor Kazal-type 5-like JBrowse link 1 229,264,277 229,343,054 RGD:1600115
G LOC100910942 serine protease inhibitor Kazal-type 6-like JBrowse link 2 36,064,130 36,076,039 RGD:1600115
G LOC100911107 leukocyte elastase inhibitor A-like JBrowse link 17 32,065,191 32,076,204 RGD:13792537
G LOC100911241 serine protease inhibitor Kazal-type 12-like JBrowse link 2 36,088,827 36,096,583 RGD:1600115
G LOC100911558 serine protease inhibitor Kazal-type 3-like JBrowse link 18 35,067,675 35,071,961 RGD:1600115
G LOC100911681 serine protease inhibitor Kazal-type 6-like JBrowse link 18 35,249,137 35,261,046 RGD:1600115
G LOC100911797 serine protease inhibitor Kazal-type 5-like JBrowse link 18 35,384,751 35,438,528 RGD:1600115
G LOC102553010 leukocyte elastase inhibitor A-like JBrowse link 17 32,009,360 32,015,101 RGD:1600115
G LOC103689965 complement C4-like JBrowse link 20 4,495,440 4,508,232 RGD:1600115
G LOC103690041 serpin B12-like JBrowse link 13 26,463,350 26,467,219 RGD:13792537
G LOC103694201 serine protease inhibitor Kazal-type 12-like JBrowse link 18 35,290,203 35,294,967 RGD:1600115
G LOC108348172 proSAAS JBrowse link X 15,425,074 15,429,397 RGD:1600115
G LOC257643 cystatin SC JBrowse link 3 143,109,366 143,116,086 RGD:1600115
G LOC296235 similar to Cystatin S precursor (LM protein) JBrowse link 3 144,480,098 144,485,304 RGD:1600115
G LOC297568 alpha-1-inhibitor III JBrowse link 4 154,505,736 154,565,104 RGD:1600115
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B JBrowse link 6 127,871,895 127,888,287 RGD:13792537
G LOC299282 Serine protease inhibitor JBrowse link 6 128,046,780 128,062,241 RGD:13792537
G LOC681544 similar to histidine-rich glycoprotein RGD:13792537
G LOC689081 similar to cystatin E2 JBrowse link 3 143,186,429 143,217,526 RGD:1600115
G LOC689220 similar to Cystatin S precursor (LM protein) JBrowse link 3 144,316,825 144,321,749 RGD:1600115
G LOC689230 similar to stefin A2 JBrowse link 11 67,329,612 67,336,910 RGD:1600115
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:8554276
G Lrp2 LDL receptor related protein 2 JBrowse link 3 55,665,153 55,822,484 RGD:8554276
G Lxn latexin JBrowse link 2 164,628,565 164,634,434 RGD:1600115
G Mug1 murinoglobulin 1 JBrowse link 4 154,676,382 154,729,288 RGD:1600115
G Mug2 murinoglobulin 2 JBrowse link 4 154,215,262 154,282,608 RGD:1600115
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:1600115
G Ngp neutrophilic granule protein JBrowse link 8 118,662,335 118,665,699 RGD:1600115
G Oprpn opiorphin prepropeptide JBrowse link 14 21,338,464 21,353,533 RGD:1600115
G P22k15 cystatin related protein 2 JBrowse link 3 143,426,001 143,430,075 RGD:1600115
G Papln papilin, proteoglycan-like sulfated glycoprotein JBrowse link 6 107,245,573 107,282,256 RGD:1600115
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor JBrowse link X 15,324,263 15,327,705 RGD:1600115
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:1600115
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1600115
G Pttg1 PTTG1 regulator of sister chromatid separation, securin JBrowse link 10 29,014,332 29,026,088 RGD:1600115
G Pzp pregnancy-zone protein JBrowse link 4 161,804,792 161,850,877 RGD:1600115
G Rarres1 retinoic acid receptor responder 1 JBrowse link 2 164,650,722 164,684,982 RGD:1600115
G Reck reversion-inducing-cysteine-rich protein with kazal motifs JBrowse link 5 59,348,568 59,415,169 RGD:13792537
G Renbp renin binding protein JBrowse link X 156,854,490 156,863,548 RGD:727355
G RGD1565462 similar to BC049975 protein JBrowse link 6 127,927,709 127,935,068 RGD:13792537
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 1,273,490 1,390,790 RGD:1600115
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:13792537
G Serpina10 serpin family A member 10 JBrowse link 6 127,500,014 127,508,470 RGD:13792537
G Serpina11 serpin family A member 11 JBrowse link 6 127,647,180 127,656,603 RGD:13792537
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:13792537
G Serpina16 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16 JBrowse link 6 127,544,773 127,552,151 RGD:13792537
G Serpina1f serine (or cysteine) peptidase inhibitor, clade A, member 1F JBrowse link 6 127,564,811 127,571,016 RGD:13792537
G Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C JBrowse link 6 127,996,162 128,003,433 RGD:13792537
G Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M JBrowse link 6 127,808,785 127,816,067 RGD:13792537
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N JBrowse link 6 128,073,344 128,080,878 RGD:13792537
G Serpina4 serpin family A member 4 JBrowse link 6 127,743,883 127,753,047 RGD:13792537
G Serpina5 serpin family A member 5 JBrowse link 6 127,753,152 127,772,403 RGD:13792537
G Serpina6 serpin family A member 6 JBrowse link 6 127,523,948 127,534,178 RGD:13792537
G Serpina7 serpin family A member 7 JBrowse link X 110,226,565 110,232,202 RGD:13792537
G Serpina9 serpin family A member 9 JBrowse link 6 127,662,348 127,680,232 RGD:13792537
G Serpinb10 serpin family B member 10 JBrowse link 13 27,466,036 27,483,789 RGD:13792537
G Serpinb11 serpin family B member 11 JBrowse link 13 27,217,385 27,257,181 RGD:13792537
G Serpinb12 serpin family B member 12 JBrowse link 13 26,970,824 26,999,709 RGD:13792537
G Serpinb13 serpin family B member 13 JBrowse link 13 27,032,048 27,062,620 RGD:1624291
RGD:13792537
G Serpinb1a serpin family B member 1A JBrowse link 17 32,903,089 32,911,498 RGD:13792537
RGD:1624291
G Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b JBrowse link 17 32,550,351 32,559,423 RGD:13792537
G Serpinb2 serpin family B member 2 JBrowse link 13 27,449,907 27,463,015 RGD:13792537
G Serpinb3 serpin family B member 3 JBrowse link 13 27,186,701 27,193,211 RGD:1624291
RGD:13792537
G Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A JBrowse link 13 27,153,500 27,159,319 RGD:13792537
G Serpinb5 serpin family B member 5 JBrowse link 13 26,903,052 26,923,250 RGD:1600115
RGD:13792537
G Serpinb6a serpin family B member 6A JBrowse link 17 32,154,747 32,209,598 RGD:1624291
RGD:13792537
G Serpinb6b serine (or cysteine) peptidase inhibitor, clade B, member 6b JBrowse link 17 32,770,488 32,787,835 RGD:13792537
G Serpinb7 serpin family B member 7 JBrowse link 13 27,282,456 27,354,775 RGD:13792537
G Serpinb8 serpin family B member 8 JBrowse link 13 27,876,662 27,914,038 RGD:1624291
RGD:13792537
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
RGD:13792537
G Serpinb9d serine (or cysteine) peptidase inhibitor, clade B, member 9d JBrowse link 17 32,516,679 32,524,336 RGD:13792537
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:13792537
G Serpind1 serpin family D member 1 JBrowse link 11 87,913,814 87,924,880 RGD:1600115
RGD:13792537
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:13792537
RGD:1600115
RGD:8554276
RGD:8547889
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1600115
RGD:13792537
G Serpine3 serpin family E member 3 JBrowse link 15 45,827,983 45,855,952 RGD:13792537
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:13792537
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:13792537
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:13792537
G Serpinh1 serpin family H member 1 JBrowse link 1 164,301,010 164,308,306 RGD:1600115
RGD:13792537
G Serpini1 serpin family I member 1 JBrowse link 2 174,013,058 174,111,693 RGD:13792537
G Serpini2 serpin family I member 2 JBrowse link 2 173,640,385 173,670,790 RGD:13792537
G Slpi secretory leukocyte peptidase inhibitor JBrowse link 3 160,799,979 160,802,228 RGD:1600115
G Smr3a submaxillary gland androgen regulated protein 3A JBrowse link 14 21,703,336 21,709,074 RGD:1600115
G Smr3b submaxillary gland androgen regulated protein 3B JBrowse link 14 21,490,216 21,709,077 RGD:1600115
G Spink13 serine peptidase inhibitor Kazal type 13 JBrowse link 18 57,935,271 58,081,096 RGD:1600115
G Spink14 serine peptidase inhibitor, Kazal type 14 JBrowse link 1 229,349,133 229,351,168 RGD:1600115
G Spink1l serine peptidase inhibitor, Kazal type 1-like JBrowse link 18 38,177,441 38,185,812 RGD:1600115
G Spink4 serine peptidase inhibitor, Kazal type 4 JBrowse link 5 57,238,221 57,252,654 RGD:1600115
G Spink5 serine peptidase inhibitor, Kazal type 5 JBrowse link 18 35,118,300 35,190,458 RGD:1600115
G Spink6 serine peptidase inhibitor, Kazal type 6 JBrowse link X 43,033,066 43,044,975 RGD:1600115
G Spink7 serine peptidase inhibitor, Kazal type 7 JBrowse link 18 57,916,369 57,920,169 RGD:1600115
G Spink9 serine peptidase inhibitor, Kazal type 9 JBrowse link X 43,012,612 43,020,370 RGD:1600115
G Spint1 serine peptidase inhibitor, Kunitz type 1 JBrowse link 3 111,049,132 111,061,991 RGD:1600115
G Spint2 serine peptidase inhibitor, Kunitz type, 2 JBrowse link 1 87,199,373 87,221,826 RGD:1600115
G Spint3 serine peptidase inhibitor, Kunitz type, 3 JBrowse link 3 161,024,739 161,028,927 RGD:1600115
G Spint5p serine peptidase inhibitor, Kunitz type 5 JBrowse link 3 161,178,117 161,179,744 RGD:1600115
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 JBrowse link 17 7,675,531 7,797,863 RGD:1624291
RGD:1600115
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 JBrowse link 16 28,372,067 28,716,762 RGD:1624291
G Stfa2 stefin A2 JBrowse link 11 67,466,126 67,471,011 RGD:1600115
G Stfa2l1 stefin A2-like 1 JBrowse link 11 67,395,889 67,400,201 RGD:1600115
G Stfa3 stefin A3 JBrowse link 11 67,309,046 67,314,181 RGD:1600115
G Stfa3l1 stefin A3-like 1 JBrowse link 11 67,543,578 67,551,211 RGD:1600115
G Tfpi tissue factor pathway inhibitor JBrowse link 3 71,852,738 71,902,127 RGD:1600115
G Tfpi2 tissue factor pathway inhibitor 2 JBrowse link 4 28,947,951 28,953,261 RGD:1600115
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:1624291
RGD:13792537
RGD:1600115
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:13792537
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:13792537
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:13792537
G Ube2o ubiquitin-conjugating enzyme E2O JBrowse link 10 105,505,721 105,553,167 RGD:1600115
G Ube2z ubiquitin-conjugating enzyme E2Z JBrowse link 10 83,869,703 83,888,823 RGD:1600115
G Uchl5 ubiquitin C-terminal hydrolase L5 JBrowse link 13 60,568,102 60,603,812 RGD:1600115
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1600115
G Vcsa2 variable coding sequence A2 JBrowse link 14 21,558,489 21,564,115 RGD:1600115
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:1624291
G Wfdc1 WAP four-disulfide core domain 1 JBrowse link 19 52,313,771 52,332,721 RGD:1600115
G Wfdc12 WAP four-disulfide core domain 12 JBrowse link 3 160,581,449 160,581,798 RGD:1600115
G Wfdc15b WAP four-disulfide core domain 15B JBrowse link 3 160,607,059 160,617,212 RGD:1600115
G Wfdc2 WAP four-disulfide core domain 2 JBrowse link 3 161,018,497 161,045,469 RGD:1600115
G Wfdc6a WAP four-disulfide core domain 6A JBrowse link 3 161,036,703 161,040,511 RGD:1600115
G Wfdc6b WAP four-disulfide core domain 6B JBrowse link 3 161,071,019 161,078,173 RGD:1600115
G Wfdc8 WAP four-disulfide core domain 8 JBrowse link 3 161,058,217 161,067,358 RGD:1600115
G Wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 JBrowse link 10 15,243,429 15,245,757 RGD:1600115
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 JBrowse link 10 81,936,156 81,943,142 RGD:1600115
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:1624291
RGD:1600115
RGD:13792537
G Cst7 cystatin F JBrowse link 3 146,363,913 146,373,365 RGD:1600115
RGD:1624291
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047164
RGD:10047212
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Fcmr Fc fragment of IgM receptor JBrowse link 13 47,602,701 47,617,065 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csn2 casein beta JBrowse link 14 21,972,274 21,979,511 RGD:1624291
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792722
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:6902918
G Ltf lactotransferrin JBrowse link 8 119,290,416 119,313,261 RGD:1624291
RGD:1600115
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
G Pcid2 PCI domain containing 2 JBrowse link 16 81,757,582 81,783,047 RGD:1624291
RGD:1600115
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07029605.1 RGD:1600115
G AC135826.1 RGD:1600115
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625666
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:1600115
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:2313324
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 JBrowse link 1 187,770,160 187,779,675 RGD:1624291
RGD:1600115
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5510006
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:1624291
RGD:1600115
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1600115
RGD:1624291
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Cd27 CD27 molecule JBrowse link 4 157,744,881 157,751,609 RGD:1600115
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1600115
RGD:1624291
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:1624291
RGD:1600115
G Cryaa crystallin, alpha A JBrowse link 20 10,438,444 10,442,189 RGD:1624291
RGD:1600115
G Cryab crystallin, alpha B JBrowse link 8 55,178,543 55,182,546 RGD:1624291
RGD:1600115
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:1624291
RGD:1600115
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
RGD:1600115
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:1624291
RGD:1600115
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 JBrowse link 4 2,711,329 2,774,969 RGD:1624291
G Dpep1 dipeptidase 1 JBrowse link 19 55,973,447 55,998,830 RGD:1624291
RGD:1600115
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:7327216
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1624291
RGD:1600115
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:1600634
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1626654
RGD:1624291
G Igbp1 immunoglobulin binding protein 1 JBrowse link X 70,322,764 70,345,005 RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1600072
G Il24 interleukin 24 JBrowse link 13 47,618,451 47,623,849 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306937
G Ints1 integrator complex subunit 1 JBrowse link 12 16,950,704 16,974,896 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G Lamp3 lysosomal-associated membrane protein 3 JBrowse link 11 84,930,965 85,000,694 RGD:1624291
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:1624291
RGD:1600115
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1600115
RGD:13792537
RGD:1624291
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317361
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 JBrowse link 20 46,199,981 46,211,930 RGD:1624291
RGD:1600115
G Mir494 microRNA 494 JBrowse link 6 133,864,370 133,864,452 RGD:1624291
G Mrtfa myocardin related transcription factor A JBrowse link 7 122,233,196 122,403,661 RGD:1624291
RGD:1600115
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
G Naip6 NLR family, apoptosis inhibitory protein 6 JBrowse link 2 30,377,505 30,418,578 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:8553292
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1600115
RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:1600115
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1600115
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
RGD:1600115
G Ptma prothymosin alpha JBrowse link 9 93,545,396 93,549,436 RGD:734494
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
RGD:1600115
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:1600115
RGD:1624291
G Rps6ka3 ribosomal protein S6 kinase A3 JBrowse link X 37,469,736 37,576,055 RGD:1624291
RGD:1600115
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1600115
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
RGD:1600115
G Sh3rf1 SH3 domain containing ring finger 1 JBrowse link 16 32,062,425 32,227,526 RGD:1624291
RGD:1600115
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 2 148,874,151 148,891,900 RGD:1624291
RGD:1600115
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
RGD:1600115
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Tfap2b transcription factor AP-2 beta JBrowse link 9 25,410,669 25,440,568 RGD:1600115
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
RGD:1600115
G Tnfaip8 TNF alpha induced protein 8 JBrowse link 18 44,664,310 44,779,914 RGD:1600115
G Tnfsf14 TNF superfamily member 14 JBrowse link 9 9,761,363 9,765,461 RGD:1600115
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 12 46,987,404 46,989,906 RGD:1624291
G Usp47 ubiquitin specific peptidase 47 JBrowse link 1 176,854,589 176,937,763 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1600115
G Wnt9a Wnt family member 9A JBrowse link 10 45,659,045 45,686,103 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Caap1 caspase activity and apoptosis inhibitor 1 JBrowse link 5 113,479,416 113,532,961 RGD:1624291
RGD:13792537
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1624291
RGD:1600115
G Nle1 notchless homolog 1 JBrowse link 10 70,250,959 70,261,880 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
RGD:1600115
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:1624291
RGD:1600115
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100910732 serine/threonine-protein kinase PAK 2-like JBrowse link 11 71,959,058 72,021,252 RGD:13792537
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:1624291
RGD:13792537
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase JBrowse link 10 70,157,621 70,220,618 RGD:1624291
RGD:1600115
G Rnf34 ring finger protein 34 JBrowse link 12 39,164,290 39,185,209 RGD:1624291
RGD:1600115
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Reck reversion-inducing-cysteine-rich protein with kazal motifs JBrowse link 5 59,348,568 59,415,169 RGD:1624291
RGD:13792537
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:1624291
RGD:1600115
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Picalm phosphatidylinositol binding clathrin assembly protein JBrowse link 1 154,377,229 154,458,966 RGD:1624291
RGD:1600115
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:1624291
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa8 annexin A8 JBrowse link 16 10,417,174 10,432,388 RGD:1624291
RGD:13792537
G LOC100910138 serine protease inhibitor Kazal-type 2-like JBrowse link 14 33,906,836 33,913,448 RGD:13792537
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:7411612
G Spink1 serine peptidase inhibitor, Kazal type 1 JBrowse link 18 38,221,919 38,242,092 RGD:724699
RGD:1624291
G Spink2 serine peptidase inhibitor, Kazal type 2 JBrowse link 14 33,247,278 33,253,913 RGD:1624291
RGD:13792537
G Spink5 serine peptidase inhibitor, Kazal type 5 JBrowse link 18 35,118,300 35,190,458 RGD:1624291
G Spink6 serine peptidase inhibitor, Kazal type 6 JBrowse link X 43,033,066 43,044,975 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      primary metabolic process 10404
        protein metabolic process 5975
          proteolysis 1829
            negative regulation of proteolysis 404
              negative regulation of peptidase activity 301
                negative regulation of endopeptidase activity 282
                  negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 2
                  negative regulation of cysteine-type endopeptidase activity + 100
                  negative regulation of metalloendopeptidase activity + 4
                  negative regulation of serine-type endopeptidase activity 7
Path 2
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      organic substance metabolic process 10932
        macromolecule metabolic process 9412
          protein metabolic process 5975
            cellular protein metabolic process 5303
              regulation of cellular protein metabolic process 2745
                negative regulation of cellular protein metabolic process 1111
                  negative regulation of proteolysis 404
                    negative regulation of peptidase activity 301
                      negative regulation of endopeptidase activity 282
                        negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 2
                        negative regulation of cysteine-type endopeptidase activity + 100
                        negative regulation of metalloendopeptidase activity + 4
                        negative regulation of serine-type endopeptidase activity 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.