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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vitamin D biosynthetic process
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Accession:GO:0010957 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


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negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      biosynthetic process 5985
        negative regulation of biosynthetic process 1628
          negative regulation of cellular biosynthetic process 1586
            negative regulation of vitamin D biosynthetic process 5
              negative regulation of calcidiol 1-monooxygenase activity 3
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13444
      regulation of biological process 12747
        regulation of metabolic process 6579
          regulation of primary metabolic process 5834
            regulation of lipid metabolic process 375
              regulation of steroid metabolic process 110
                negative regulation of steroid metabolic process 25
                  negative regulation of steroid biosynthetic process 24
                    negative regulation of vitamin D biosynthetic process 5
                      negative regulation of calcidiol 1-monooxygenase activity 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.