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ONTOLOGY REPORT - ANNOTATIONS


Term:neural crest cell differentiation
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Accession:GO:0014033 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.


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neural crest cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1624291
RGD:1600115
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
RGD:13792537
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:1624291
RGD:1600115
G Wnt10a Wnt family member 10A JBrowse link 9 82,053,581 82,066,047 RGD:1624291
canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
cardiac neural crest cell development involved in heart development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 JBrowse link 1 12,823,363 12,825,806 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1624291
RGD:1600115
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
RGD:1600115
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
neural crest cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 JBrowse link 8 77,640,234 77,719,488 RGD:1624291
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:1624291
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 JBrowse link 1 256,369,410 256,380,649 RGD:1624291
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:1624291
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1600115
RGD:1624291
G Fam172a family with sequence similarity 172, member A JBrowse link 2 4,942,795 5,547,744 RGD:1624291
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:1624291
G Foxc2 forkhead box C2 JBrowse link 19 53,044,379 53,047,081 RGD:1624291
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Kbtbd8 kelch repeat and BTB domain containing 8 JBrowse link 4 127,164,728 127,177,537 RGD:1600115
RGD:1624291
G Klhl12 kelch-like family member 12 JBrowse link 13 51,280,933 51,314,753 RGD:1600115
RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:1624291
G Nolc1 nucleolar and coiled-body phosphoprotein 1 JBrowse link 1 265,829,055 265,839,819 RGD:1624291
RGD:1600115
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pef1 penta-EF hand domain containing 1 JBrowse link 5 148,320,610 148,343,876 RGD:1624291
RGD:1600115
G Rdh10 retinol dehydrogenase 10 JBrowse link 5 2,605,265 2,631,905 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Sox11 SRY-box transcription factor 11 JBrowse link 6 46,629,967 46,631,988 RGD:1624291
RGD:1600115
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:13792537
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Tcof1 treacle ribosome biogenesis factor 1 JBrowse link 18 56,081,863 56,115,719 RGD:1624291
G Tfap2a transcription factor AP-2 alpha JBrowse link 17 24,653,342 24,670,457 RGD:1624291
neural crest cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:1624291
RGD:1600115
neural crest cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gsc goosecoid homeobox JBrowse link 6 128,147,181 128,149,220 RGD:1624291
neural crest cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1 activin A receptor type 1 JBrowse link 3 44,432,476 44,539,680 RGD:1624291
RGD:1600115
G Alx1 ALX homeobox 1 JBrowse link 7 44,751,865 44,771,458 RGD:1600115
G Anxa6 annexin A6 JBrowse link 10 40,320,581 40,375,605 RGD:13792537
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:1624291
G Coro1c coronin 1C JBrowse link 12 48,481,741 48,554,054 RGD:1624291
RGD:13792537
G Edn3 endothelin 3 JBrowse link 3 172,856,730 172,879,276 RGD:1624291
G Ednrb endothelin receptor type B JBrowse link 15 88,004,775 88,036,354 RGD:1624291
G Efnb1 ephrin B1 JBrowse link X 68,891,227 68,904,034 RGD:1624291
RGD:1600115
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1600115
RGD:1624291
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:1624291
G Gbx2 gastrulation brain homeobox 2 JBrowse link 9 97,063,265 97,065,855 RGD:1624291
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:1624291
RGD:1600115
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:1624291
G Lama5 laminin subunit alpha 5 JBrowse link 3 175,553,042 175,601,112 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Nrtn neurturin JBrowse link 9 10,299,881 10,306,599 RGD:1624291
G Ovol2 ovo-like zinc finger 2 JBrowse link 3 138,433,990 138,464,511 RGD:1624291
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:1624291
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:8552342
G Phactr4 phosphatase and actin regulator 4 JBrowse link 5 150,533,895 150,609,423 RGD:1624291
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:13792537
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:13792537
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
RGD:13792537
G Sema3d semaphorin 3D JBrowse link 4 19,224,378 19,413,519 RGD:13792537
G Sema3e semaphorin 3E JBrowse link 4 17,314,745 17,594,659 RGD:13792537
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
RGD:13792537
G Sema3g semaphorin 3G JBrowse link 16 7,303,582 7,315,214 RGD:13792537
G Sema4a semaphorin 4A JBrowse link 2 187,799,568 187,823,014 RGD:13792537
G Sema4b semaphorin 4B JBrowse link 1 141,986,145 142,014,400 RGD:13792537
G Sema4c semaphorin 4C JBrowse link 9 43,129,413 43,140,442 RGD:13792537
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:13792537
G Sema4f ssemaphorin 4F JBrowse link 4 113,738,225 113,764,532 RGD:13792537
G Sema4g semaphorin 4G JBrowse link 1 264,738,935 264,753,399 RGD:13792537
G Sema6a semaphorin 6A JBrowse link 18 41,330,519 41,451,813 RGD:13792537
G Sema6b semaphorin 6B JBrowse link 9 10,934,273 10,951,252 RGD:13792537
G Sema6c semaphorin 6C JBrowse link 2 196,330,777 196,347,218 RGD:13792537
G Sema6d semaphorin 6D JBrowse link 3 116,899,906 116,958,059 RGD:13792537
G Sema7a semaphorin 7A (John Milton Hagen blood group) JBrowse link 8 62,723,788 62,746,530 RGD:13792537
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:1624291
RGD:1600115
G Sox10 SRY-box transcription factor 10 JBrowse link 7 120,393,238 120,403,523 RGD:1624291
RGD:13792537
G Sox8 SRY-box transcription factor 8 JBrowse link 10 14,932,348 14,937,336 RGD:1624291
RGD:1600115
G Tbx1 T-box transcription factor 1 JBrowse link 11 86,552,022 86,561,647 RGD:1600115
RGD:1624291
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link 3 29,857,289 29,985,932 RGD:1624291
neural crest cell migration involved in autonomic nervous system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:1600115
RGD:1624291
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Phox2b paired-like homeobox 2b JBrowse link 14 42,711,169 42,718,707 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291
neural crest cell migration involved in heart formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:1624291
neural crest cell migration involved in sympathetic nervous system development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
G Sema3c semaphorin 3C JBrowse link 4 14,318,276 14,490,438 RGD:1624291
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eng endoglin JBrowse link 3 11,679,530 11,717,486 RGD:1624291
regulation of neural crest cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
regulation of neural crest cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
ventral trunk neural crest cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:1624291
G Nrp2 neuropilin 2 JBrowse link 9 69,496,875 69,609,802 RGD:1624291
G Sema3a semaphorin 3A JBrowse link 4 18,170,375 18,545,190 RGD:1624291
G Sema3f semaphorin 3F JBrowse link 8 116,439,996 116,469,915 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    cellular process 17240
      cellular developmental process 4415
        cell differentiation 4195
          mesenchymal cell differentiation 219
            neural crest cell differentiation 91
              canonical Wnt signaling pathway involved in neural crest cell differentiation + 1
              cardiac neural crest cell differentiation involved in heart development + 16
              negative regulation of neural crest cell differentiation + 0
              neural crest cell development + 84
              neural crest cell differentiation involved in parathyroid gland development 0
              neural crest cell differentiation involved in thymus development 0
              neural crest cell fate commitment + 3
              positive regulation of neural crest cell differentiation + 3
              regulation of neural crest cell differentiation + 5
Path 2
Term Annotations click to browse term
  biological_process 19336
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            animal organ development 3898
              mesenchyme development 279
                mesenchymal cell differentiation 219
                  neural crest cell differentiation 91
                    canonical Wnt signaling pathway involved in neural crest cell differentiation + 1
                    cardiac neural crest cell differentiation involved in heart development + 16
                    negative regulation of neural crest cell differentiation + 0
                    neural crest cell development + 84
                    neural crest cell differentiation involved in parathyroid gland development 0
                    neural crest cell differentiation involved in thymus development 0
                    neural crest cell fate commitment + 3
                    positive regulation of neural crest cell differentiation + 3
                    regulation of neural crest cell differentiation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.