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ONTOLOGY REPORT - ANNOTATIONS


Term:dopamine secretion
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Accession:GO:0014046 term browser browse the term
Definition:The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.


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negative regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:590329 RGD:10047092 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G C5 complement C5 IDA RGD PMID:18648551 RGD:5130170 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19187091 RGD:2314679 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:16490190 RGD:1625068 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IDA RGD PMID:12872287 RGD:2315496 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Syt11 synaptotagmin 11 IDA
ISO
PMID:29311685
(MGI:6114813|PMID:29311685)
RGD PMID:29311685, PMID:29311685 MGI:6114813, RGD:14929208 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
positive regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253 (MGI:1194464|PMID:9428762) RGD PMID:9428762 MGI:1194464 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IDA RGD PMID:18671738 RGD:2306573 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:17382974 RGD:1642505 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Oprk1 opioid receptor, kappa 1 IDA RGD PMID:17568430 RGD:9831445 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Pcp4 Purkinje cell protein 4 IMP RGD PMID:21671256 RGD:9850149 NCBI chr11:36,851,035...36,912,272
Ensembl chr11:36,851,038...36,912,229
JBrowse link
G Pink1 PTEN induced kinase 1 ISO MGI:3716083 (MGI:3715376|PMID:17563363) RGD PMID:17563363 MGI:3715376 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Rtn4 reticulon 4 IMP RGD PMID:19112410 RGD:2314933 NCBI chr14:114,126,931...114,174,459
Ensembl chr14:114,126,943...114,174,458
JBrowse link
G Slc18a1 solute carrier family 18 member A1 IMP RGD PMID:17244889 RGD:5131195 NCBI chr16:22,358,646...22,395,183
Ensembl chr16:22,361,998...22,395,183
JBrowse link
G Syt1 synaptotagmin 1 IMP PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
regulation of dopamine secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit IEA
ISO
GO_REF:0000107
MGI:1926251 (MGI:2673776|PMID:12944511)
Ensembl
RGD
PMID:12944511 GO_REF:0000107, MGI:2673776 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit IEA
ISO
GO_REF:0000107
MGI:2179133 (MGI:2673776|PMID:12944511)
Ensembl
RGD
PMID:12944511 GO_REF:0000107, MGI:2673776 NCBI chr16:68,860,018...68,866,718
Ensembl chr16:68,860,018...68,866,718
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253 (MGI:2673776|PMID:12944511) RGD PMID:12944511 MGI:2673776 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Drd2 dopamine receptor D2 IBA
ISO
PMID:21873635
MGI:2387895|MGI:2675755 (MGI:3655899|PMID:11943831)
RGD PMID:11943831, PMID:21873635 MGI:3655899, RGD:13792537 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IBA
ISO
IMP
PMID:21873635
MGI:3044114|MGI:3698033 (MGI:1202050|PMID:9482807), (MGI:3698022|PMID:12044470)
RGD PMID:9482807, PMID:12044470, PMID:21873635, PMID:16490190 MGI:1202050, MGI:3698022, RGD:13792537, RGD:1625068 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 ISS
ISO
IEA
GO_REF:0000024
(MGI:4398782|PMID:19887632)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19887632 GO_REF:0000024, GO_REF:0000107, MGI:4398782 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206
JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP RGD PMID:30283001 RGD:38501063 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:16885935 RGD:1626459 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:15999145 RGD:1624397 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 ISS
ISO
GO_REF:0000024
(MGI:4947004|PMID:21233214)
UniProt
RGD
PMID:21233214 GO_REF:0000024, MGI:4947004 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Prkcb protein kinase C, beta IMP RGD PMID:15647254 RGD:1625522 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Rab3a RAB3A, member RAS oncogene family IDA PMID:28370453 CACAO PMID:28370453 RGD:15023476 NCBI chr16:20,435,098...20,439,206
Ensembl chr16:20,435,101...20,439,206
JBrowse link
G Snca synuclein alpha ISO MGI:1298397 (MGI:3777215|PMID:18333965) RGD PMID:18333965 MGI:3777215 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sncg synuclein, gamma IEA
ISO
GO_REF:0000107
MGI:1277151 (MGI:3777215|PMID:18333965)
Ensembl
RGD
PMID:18333965 GO_REF:0000107, MGI:3777215 NCBI chr16:10,722,110...10,726,648
Ensembl chr16:10,722,106...10,726,707
JBrowse link
G Syt1 synaptotagmin 1 IBA
ISO
PMID:21873635
(MGI:5795818|PMID:21576241)
RGD PMID:21576241, PMID:21873635 MGI:5795818, RGD:13792537 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Syt10 synaptotagmin 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:130,769,039...130,827,030
Ensembl chr 7:130,768,841...130,827,152
JBrowse link
G Syt11 synaptotagmin 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,112,301...188,138,180
Ensembl chr 2:188,112,286...188,138,177
JBrowse link
G Syt12 synaptotagmin 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:219,690,013...219,719,359
Ensembl chr 1:219,688,451...219,719,272
JBrowse link
G Syt13 synaptotagmin 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:81,814,287...81,852,454
Ensembl chr 3:81,814,261...81,854,605
JBrowse link
G Syt15 synaptotagmin 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,554,136...10,564,934
Ensembl chr16:10,554,136...10,564,927
JBrowse link
G Syt17 synaptotagmin 17 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,034,614...188,101,590
Ensembl chr 1:188,034,495...188,101,566
JBrowse link
G Syt2 synaptotagmin 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:51,569,248...51,577,824
Ensembl chr13:51,534,025...51,578,052
JBrowse link
G Syt3 synaptotagmin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:100,379,236...100,407,862
Ensembl chr 1:100,379,186...100,408,083
JBrowse link
G Syt4 synaptotagmin 4 IBA
ISO
PMID:21873635
(MGI:5795818|PMID:21576241)
RGD PMID:21576241, PMID:21873635 MGI:5795818, RGD:13792537 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
G Syt5 synaptotagmin 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:72,859,806...72,867,934
Ensembl chr 1:72,860,218...72,867,930
JBrowse link
G Syt6 synaptotagmin 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:206,064,181...206,119,034
Ensembl chr 2:206,064,179...206,127,907
JBrowse link
G Syt7 synaptotagmin 7 IBA
ISO
PMID:21873635
(MGI:5795818|PMID:21576241)
RGD PMID:21576241, PMID:21873635 MGI:5795818, RGD:13792537 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Syt8 synaptotagmin 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:215,605,408...215,607,602
Ensembl chr 1:215,605,404...215,607,696
JBrowse link
G Syt9 synaptotagmin 9 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:171,592,703...171,769,780
Ensembl chr 1:171,592,797...171,769,780
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    signaling 7579
      cell-cell signaling 1727
        signal release 617
          dopamine secretion 42
            axonal dopamine secretion + 0
            negative regulation of dopamine secretion 7
            positive regulation of dopamine secretion 10
            regulation of dopamine secretion + 42
            somato-dendritic dopamine secretion 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    localization 6478
      establishment of localization 4886
        transport 4734
          ion transport 3500
            anion transport 2681
              organic substance transport 2558
                monoamine transport 106
                  catecholamine transport 90
                    catecholamine secretion 72
                      dopamine secretion 42
                        axonal dopamine secretion + 0
                        negative regulation of dopamine secretion 7
                        positive regulation of dopamine secretion 10
                        regulation of dopamine secretion + 42
                        somato-dendritic dopamine secretion 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.