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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamate secretion
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Accession:GO:0014047 term browser browse the term
Definition:The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.


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glutamate secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apba1 amyloid beta precursor protein binding family A member 1 IEA
ISO
GO_REF:0000107
MGI:1261791 (MGI:3691953|PMID:17167098)
Ensembl
RGD
PMID:17167098 GO_REF:0000107, MGI:3691953 NCBI chr 1:241,594,565...241,796,512
Ensembl chr 1:241,594,565...241,796,513
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO PR:P15209 (MGI:3654775|PMID:16819522) RGD PMID:16819522 MGI:3654775 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 ISO MGI:3663921 (MGI:3654775|PMID:16819522) RGD PMID:16819522 MGI:3654775 NCBI chr19:24,786,604...24,798,231
Ensembl chr19:24,786,628...24,798,233
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO (MGI:6368305|PMID:26200696) RGD PMID:26200696 MGI:6368305 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Grm2 glutamate metabotropic receptor 2 IDA PMID:15993439 UniProt PMID:15993439 RGD:8553886 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Myo6 myosin VI ISO MGI:1856555 (MGI:3654775|PMID:16819522) RGD PMID:16819522 MGI:3654775 NCBI chr 8:87,583,649...87,731,271
Ensembl chr 8:87,630,916...87,731,269
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IEA
ISO
GO_REF:0000107
UniProtKB:P21237 (MGI:3654775|PMID:16819522)
Ensembl
RGD
PMID:16819522 GO_REF:0000107, MGI:3654775 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IDA RGD PMID:18480286 RGD:2317101 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
glutamate secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nf1 neurofibromin 1 IEA
ISO
GO_REF:0000107
MGI:1339975 (MGI:5620820|PMID:25242307)
Ensembl
RGD
PMID:25242307 GO_REF:0000107, MGI:5620820 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 ISO MGI:97306 (MGI:5620820|PMID:25242307) RGD PMID:25242307 MGI:5620820 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
negative regulation of glutamate secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Grm7 glutamate metabotropic receptor 7 IDA RGD PMID:11825890, PMID:12692128 RGD:728749, RGD:2289010 NCBI chr 4:142,452,616...143,368,460
Ensembl chr 4:142,780,987...143,367,578
JBrowse link
G Hrh3 histamine receptor H3 IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:17027043, PMID:21873635 RGD:1626422, RGD:13792537 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Il1b interleukin 1 beta IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:12623227 RGD:1625502 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:10081919 RGD:7777119 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Trh thyrotropin releasing hormone IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16055093, PMID:21873635 RGD:1600422, RGD:13792537 NCBI chr 4:124,110,716...124,113,242
Ensembl chr 4:124,110,716...124,113,242
JBrowse link
positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtnbp1 dystrobrevin binding protein 1 IMP RGD PMID:15345706 RGD:11251758 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 ISS
ISO
GO_REF:0000024
(MGI:3652690|PMID:16782817)
ParkinsonsUK-UCL
RGD
PMID:16782817 GO_REF:0000024, MGI:3652690 NCBI chr13:44,578,208...44,649,876
Ensembl chr13:44,615,553...44,648,620
JBrowse link
positive regulation of glutamate secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Avp arginine vasopressin IMP RGD PMID:17877638 RGD:2300342 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A IMP RGD PMID:17877638 RGD:2300342 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr1b arginine vasopressin receptor 1B IMP RGD PMID:17877638 RGD:2300342 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Cck cholecystokinin IDA PMID:20392936 CACAO PMID:20392936 RGD:10047227 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IDA RGD PMID:19755421 RGD:2316240 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IMP RGD PMID:18765663 RGD:7241136 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IDA PMID:16407536 UniProt PMID:16407536 RGD:8553534 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Kmo kynurenine 3-monooxygenase IMP RGD PMID:15829251 RGD:13513901 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:19484722 RGD:4892315 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:18063561 RGD:9743970 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G P2rx7 purinergic receptor P2X 7 ISO MGI:2386080 (MGI:3610634|PMID:15640761), (MGI:3700006|PMID:17306762) RGD PMID:15640761, PMID:17306762 MGI:3610634, MGI:3700006 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Syt4 synaptotagmin 4 ISO (MGI:3047044|PMID:15197251) RGD PMID:15197251 MGI:3047044 NCBI chr18:24,172,580...24,181,989
Ensembl chr18:24,172,587...24,182,012
JBrowse link
positive regulation of glutamate secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase IMP RGD PMID:15829251 RGD:13513901 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:16951547 RGD:12904030 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
regulation of glutamate secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 IDA RGD PMID:15561437 RGD:2315491 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Grm1 glutamate metabotropic receptor 1 TAS PMID:11530226 UniProt PMID:11530226 RGD:8553469 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP RGD PMID:30283001, PMID:28700935 RGD:38501063, RGD:38501064 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Snca synuclein alpha ISO MGI:2154692 (MGI:3789831|PMID:17689254) RGD PMID:17689254 MGI:3789831 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      export from cell 1006
        secretion by cell 955
          glutamate secretion 37
            glutamate secretion, neurotransmission + 6
            negative regulation of glutamate secretion + 9
            positive regulation of glutamate secretion + 16
            regulation of glutamate secretion + 28
Path 2
Term Annotations click to browse term
  biological_process 20020
    localization 6478
      establishment of localization 4886
        transport 4734
          ion transport 3500
            anion transport 2681
              organic substance transport 2558
                organic anion transport 384
                  carboxylic acid transport 299
                    dicarboxylic acid transport 99
                      glutamate secretion 37
                        glutamate secretion, neurotransmission + 6
                        negative regulation of glutamate secretion + 9
                        positive regulation of glutamate secretion + 16
                        regulation of glutamate secretion + 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.