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ONTOLOGY REPORT - ANNOTATIONS


Term:acetylcholine secretion, neurotransmission
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Accession:GO:0014055 term browser browse the term
Definition:The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).


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negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin RGD PMID:12679375 RGD:1625693 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:15266551 RGD:1625007 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Tacr2 tachykinin receptor 2 IMP RGD PMID:12747940 RGD:5147477 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA
ISO
GO_REF:0000107
MGI:MGI:1856209|MGI:MGI:2181384 (MGI:MGI:2654957|PMID:12624181), (MGI:MGI:3606714|PMID:10686170)
Ensembl
RGD
PMID:10686170, PMID:12624181 GO_REF:0000107, MGI:MGI:2654957, MGI:MGI:3606714 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO MGI:MGI:2155602 (MGI:MGI:3590443|PMID:16162937) RGD PMID:16162937 MGI:MGI:3590443 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        establishment of localization in cell 2156
          neurotransmitter secretion 198
            acetylcholine secretion, neurotransmission 6
              negative regulation of acetylcholine secretion, neurotransmission 1
              positive regulation of acetylcholine secretion, neurotransmission + 3
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        transport 4774
          secretion 1217
            secretion by cell 1020
              signal release 671
                signal release from synapse 198
                  neurotransmitter secretion 198
                    acetylcholine secretion, neurotransmission 6
                      negative regulation of acetylcholine secretion, neurotransmission 1
                      positive regulation of acetylcholine secretion, neurotransmission + 3
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.