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Term:phosphatidylinositol 3-kinase signaling
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Accession:GO:0014065 term browser browse the term
Definition:A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
Synonyms:exact_synonym: PI 3-kinase cascade;   PI3K cascade;   PI3K signal transduction;   PI3K signaling;   phosphatidylinositol 3-kinase signal transduction;   phosphoinositide 3-kinase cascade
 related_synonym: phosphatidylinositol 3-kinase cascade

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phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004955538:3,208,711...3,224,386 JBrowse link
G C1qbp complement C1q binding protein ISO (PMID:16177118) UniProtKB PMID:16177118 NCBI chrNW_004955467:10,788,142...10,792,272 JBrowse link
G Cd160 CD160 molecule ISO (PMID:17307798) UniProt PMID:17307798 NCBI chrNW_004955568:365,700...372,149 JBrowse link
G Csf2 colony stimulating factor 2 ISO (PMID:24520418) AgBase PMID:24520418 NCBI chrNW_004955408:3,452,009...3,454,255 JBrowse link
G Edn1 endothelin 1 ISO (PMID:17078114) BHF-UCL PMID:17078114 NCBI chrNW_004955465:2,287,906...2,314,945 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chrNW_004955451:14,442,816...14,456,009 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chrNW_004955458:3,683,126...3,701,752 JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:MGI:5285154|PMID:20696860) UniProtKB PMID:20696860 MGI:MGI:5285154 NCBI chrNW_004955421:24,448,446...24,477,885 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO (PMID:16517693) UniProtKB PMID:16517693 NCBI chrNW_004955431:583,165...646,991 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO (PMID:16517693) UniProtKB PMID:16517693 NCBI chrNW_004955453:4,352,278...4,367,807 JBrowse link
G Igf1 insulin like growth factor 1 ISO (PMID:24508636) AgBase PMID:24508636 NCBI chrNW_004955405:37,505,830...37,582,152 JBrowse link
G Irs1 insulin receptor substrate 1 ISO (PMID:7782332) BHF-UCL PMID:7782332 NCBI chrNW_004955453:7,685,715...7,742,262 JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 ISO (MGI:MGI:5806303|PMID:27708159) MGI PMID:27708159 MGI:MGI:5806303 NCBI chrNW_004955617:137,854...157,801 JBrowse link
G Ltk leukocyte receptor tyrosine kinase ISO (PMID:9223670) UniProtKB PMID:9223670 NCBI chrNW_004955416:8,310,304...8,319,463 JBrowse link
G Nf1 neurofibromin 1 ISO (MGI:MGI:3032882|PMID:14724565) MGI PMID:14724565 MGI:MGI:3032882 NCBI chrNW_004955481:6,145,855...6,404,179 JBrowse link
G Nyap1 neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 ISO (MGI:MGI:5304984|PMID:21946561) UniProtKB PMID:21946561 MGI:MGI:5304984 NCBI chrNW_004955573:402,180...410,729 JBrowse link
G Nyap2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 ISO (MGI:MGI:5304984|PMID:21946561) UniProtKB PMID:21946561 MGI:MGI:5304984 NCBI chrNW_004955453:8,585,848...8,859,417 JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 ISO (MGI:MGI:5817200|PMID:27614188) MGI PMID:27614188 MGI:MGI:5817200 NCBI chrNW_004955545:2,958,334...2,977,146 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO (PMID:25339672) CAFA PMID:25339672 NCBI chrNW_004955501:251,829...381,255 JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO (PMID:25339672) CAFA PMID:25339672 NCBI chrNW_004955486:3,813,923...3,837,563 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO (PMID:12507995) UniProtKB PMID:12507995 NCBI chrNW_004955410:11,402,476...11,433,335 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO (PMID:7782332)
BHF-UCL PMID:7782332, PMID:21321938 NCBI chrNW_004955446:1,020,707...1,098,327 JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004955524:3,234,111...3,241,445 JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 ISO (PMID:12507995) UniProt PMID:12507995 NCBI chrNW_004955467:8,025,231...8,091,406 JBrowse link
G Plekha1 pleckstrin homology domain containing A1 ISO (PMID:12101241) UniProtKB PMID:12101241 NCBI chrNW_004955477:659,640...730,394 JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 ISO (MGI:MGI:5550173|PMID:24367090) MGI PMID:24367090 MGI:MGI:5550173 NCBI chrNW_004955444:11,154,318...11,414,680 JBrowse link
G Sirt2 sirtuin 2 ISO (PMID:23908241) UniProtKB PMID:23908241 NCBI chrNW_004955468:626,365...644,441 JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:3050929|PMID:15249583) MGI PMID:15249583 MGI:MGI:3050929 NCBI chrNW_004955442:15,178,356...15,216,978 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:23529610) UniProtKB PMID:23529610 NCBI chrNW_004955455:3,037,885...3,041,827 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:15538381) UniProtKB PMID:15538381 NCBI chrNW_004955466:1,541,367...1,546,617 JBrowse link
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryba1 crystallin beta A1 ISO RGD PMID:21993393 RGD:10059647 NCBI chrNW_004955481:3,952,976...3,986,548 JBrowse link
G Dab2ip DAB2 interacting protein ISO (PMID:19903888) UniProtKB PMID:19903888 NCBI chrNW_004955419:6,229,437...6,416,619 JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E ISO RGD PMID:21436142 RGD:12911213 NCBI chrNW_004955513:4,304,483...4,313,087 JBrowse link
G Klf4 Kruppel like factor 4 ISO PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chrNW_004955419:19,280,311...19,284,097 JBrowse link
G Ncor1 nuclear receptor corepressor 1 ISO (MGI:MGI:3723397|PMID:17606624) MGI PMID:17606624 MGI:MGI:3723397 NCBI chrNW_004955467:1,408,292...1,568,539 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (MGI:MGI:5883388|PMID:27951586) UniProtKB PMID:27951586 MGI:MGI:5883388 NCBI chrNW_004955442:13,795,322...13,834,362 JBrowse link
G Nop53 NOP53 ribosome biogenesis factor ISO (PMID:16971513) UniProtKB PMID:16971513 NCBI chrNW_004955574:1,505,997...1,514,680 JBrowse link
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF ISO (MGI:MGI:6101642|PMID:28826662) UniProt PMID:28826662 MGI:MGI:6101642 NCBI chrNW_004955581:148,571...265,062 JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO (PMID:17475214)
UniProtKB PMID:17475214, PMID:18632611 MGI:MGI:3806716 NCBI chrNW_004955455:5,474,569...5,488,420 JBrowse link
G Serpine2 serpin family E member 2 ISO (MGI:MGI:3810206|PMID:18398001) MGI PMID:18398001 MGI:MGI:3810206 NCBI chrNW_004955453:10,049,822...10,076,155 JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 ISO (MGI:MGI:3617099|PMID:16456542) UniProtKB
PMID:16456542 MGI:MGI:3617099 NCBI chrNW_004955553:1,639,267...1,656,850 JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 ISO (MGI:MGI:3617099|PMID:16456542) MGI PMID:16456542 MGI:MGI:3617099 NCBI chrNW_004955442:15,224,214...15,235,372 JBrowse link
G Stambp STAM binding protein ISO (PMID:23542699) UniProtKB PMID:23542699 NCBI chrNW_004955424:11,831,910...11,879,577 JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:3586939|PMID:16027169) MGI PMID:16027169 MGI:MGI:3586939 NCBI chrNW_004955442:15,178,356...15,216,978 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17003487) BHF-UCL PMID:17003487 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO PMID:18469807
UniProt PMID:14528310, PMID:18469807 RGD:1299350, RGD:8553892 NCBI chrNW_004955458:5,436,544...5,448,201 JBrowse link
G Agt angiotensinogen ISO (PMID:15652490) BHF-UCL PMID:15652490 NCBI chrNW_004955492:7,863,662...7,874,863 JBrowse link
G Angpt1 angiopoietin 1 ISO (MGI:MGI:3848848|PMID:19409199) MGI PMID:19409199 MGI:MGI:3848848 NCBI chrNW_004955417:30,199,508...30,386,695 JBrowse link
G Cat catalase ISO (MGI:MGI:3037350|PMID:15020231) MGI PMID:15020231 MGI:MGI:3037350 NCBI chrNW_004955422:11,783,973...11,826,970 JBrowse link
G Cbl Cbl proto-oncogene ISO (PMID:17003487) BHF-UCL PMID:17003487 NCBI chrNW_004955412:20,307,011...20,388,539 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO PMID:10477596
BHF-UCL PMID:7544376, PMID:10477596 RGD:8553666 NCBI chrNW_004955481:10,293,758...10,301,118 JBrowse link
G Cd28 CD28 molecule ISO (MGI:MGI:5520006|PMID:23589618) MGI PMID:23589618 MGI:MGI:5520006 NCBI chrNW_004955457:11,159,769...11,253,099 JBrowse link
G Cntf ciliary neurotrophic factor ISO RGD PMID:15574731 RGD:1626128 NCBI chrNW_004955511:3,527,552...3,531,275 JBrowse link
G Csf3 colony stimulating factor 3 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004955451:14,688,181...14,690,126 JBrowse link
G Dcn decorin ISO (PMID:23798385) MGI PMID:23798385 NCBI chrNW_004955405:28,335,493...28,371,912 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:16168116 RGD:1582137 NCBI chrNW_004955451:14,442,816...14,456,009 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:MGI:3796800|PMID:18458158) MGI PMID:18458158 MGI:MGI:3796800 NCBI chrNW_004955457:3,177,905...4,236,152 JBrowse link
G F2 coagulation factor II, thrombin ISO (MGI:MGI:3810206|PMID:18398001) MGI PMID:18398001 MGI:MGI:3810206 NCBI chrNW_004955422:1,356,675...1,367,788 JBrowse link
G F2r coagulation factor II thrombin receptor ISO (MGI:MGI:5285163|PMID:20215560)
PMID:18398001, PMID:20215560 MGI:MGI:3810206, MGI:MGI:5285163 NCBI chrNW_004955425:24,144,905...24,164,498 JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (MGI:MGI:5285163|PMID:20215560) UniProtKB PMID:20215560 MGI:MGI:5285163 NCBI chrNW_004955425:24,050,901...24,054,039 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO (PMID:10739672) UniProtKB PMID:10739672 NCBI chrNW_004955452:6,840,274...6,863,460 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO (PMID:14633857) UniProtKB PMID:14633857 NCBI chrNW_004955497:7,653,309...7,831,737 JBrowse link
G Fshr follicle stimulating hormone receptor ISO (PMID:24058690) UniProtKB PMID:24058690 NCBI chrNW_004955441:15,422,190...15,585,446 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chrNW_004955411:36,403,156...36,597,660 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO (PMID:15705806) UniProtKB
PMID:15705806, PMID:19717735 RGD:4892081 NCBI chrNW_004955460:8,790,798...8,794,902 JBrowse link
G Hax1 HCLS1 associated protein X-1 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004955545:816,789...819,667 JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004955427:20,999,934...21,020,401 JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) BHF-UCL PMID:20655899 NCBI chrNW_004955410:4,114,280...4,181,953 JBrowse link
G Igf1 insulin like growth factor 1 ISO PMID:17023532
PMID:7688386, PMID:17023532, PMID:21413931 MGI:MGI:5005047, RGD:1600072 NCBI chrNW_004955405:37,505,830...37,582,152 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:25186839 RGD:10046020 NCBI chrNW_004955416:26,101,090...26,382,660 JBrowse link
G Il18 interleukin 18 ISO (PMID:21321938) BHF-UCL PMID:21321938 NCBI chrNW_004955412:13,807,361...13,826,007 JBrowse link
G Ins insulin ISO (PMID:7688386) BHF-UCL PMID:7688386 NCBI chrNW_004955422:13,909,408...13,910,419 JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:MGI:3828423|PMID:7782332) BHF-UCL PMID:7782332 MGI:MGI:3828423 NCBI chrNW_004955434:9,227,897...9,341,208 JBrowse link
G Kdr kinase insert domain receptor ISO (PMID:9804796) UniProtKB
PMID:9804796, PMID:18221855 RGD:2292019 NCBI chrNW_004955447:15,810,816...15,851,702 JBrowse link
G Lep leptin ISO (MGI:MGI:4821191|PMID:20620997)
PMID:11677594, PMID:20620997, PMID:24340098 MGI:MGI:4821191, RGD:10448951 NCBI chrNW_004955479:9,266,604...9,276,568 JBrowse link
G Maz MYC associated zinc finger protein ISO (PMID:25487955) ARUK-UCL PMID:25487955 NCBI chrNW_004955493:7,149,600...7,152,449 JBrowse link
G Mydgf myeloid derived growth factor ISO (MGI:MGI:5609664|PMID:25581518) UniProtKB PMID:25581518 MGI:MGI:5609664 NCBI chrNW_004955495:4,320,532...4,330,921 JBrowse link
G Myoc myocilin ISO (PMID:21656515) UniProtKB PMID:21656515 NCBI chrNW_004955406:12,182,115...12,194,683 JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004955456:13,353,780...13,363,956 JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO (PMID:17218260) BHF-UCL PMID:17218260 NCBI chrNW_004955409:183,645...281,252 JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO (PMID:20395202) UniProtKB PMID:20395202 NCBI chrNW_004955403:46,807,846...46,809,924 JBrowse link
G Nrg1 neuregulin 1 ISO (MGI:MGI:3796800|PMID:18458158) MGI PMID:18458158 MGI:MGI:3796800 NCBI chrNW_004955463:8,009,436...9,037,116 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO PMID:10985347 UniProt PMID:10985347 RGD:8553408 NCBI chrNW_004955432:2,284,283...2,629,631 JBrowse link
G Osm oncostatin M ISO (PMID:28972028) BHF-UCL PMID:28972028 NCBI chrNW_004955455:4,510,711...4,515,282 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO (PMID:11788434) UniProtKB PMID:11788434 NCBI chrNW_004955460:8,328,400...8,346,755 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO (PMID:10734101), (PMID:11788434), (PMID:17942966)
PMID:10734101, PMID:11788434, PMID:16456542, PMID:17942966 MGI:MGI:3617099 NCBI chrNW_004955413:25,150,702...25,166,987 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO (MGI:MGI:5009390|PMID:17942966) UniProtKB PMID:17942966 MGI:MGI:5009390 NCBI chrNW_004955415:4,365,848...4,403,317 JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO (MGI:MGI:5305503|PMID:22187460), (MGI:MGI:5305504|PMID:22187458) UniProtKB PMID:22187458, PMID:22187460 MGI:MGI:5305503, MGI:MGI:5305504 NCBI chrNW_004955507:2,805,782...2,918,664 JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:15705590 RGD:2299907 NCBI chrNW_004955467:10,239,177...10,250,516 JBrowse link
G Plxnb1 plexin B1 ISO (MGI:MGI:4413657|PMID:19788569) UniProtKB PMID:19788569 MGI:MGI:4413657 NCBI chrNW_004955532:471,652...499,525 JBrowse link
G Prr5 proline rich 5 ISO (MGI:MGI:5005047|PMID:21413931) MGI PMID:21413931 MGI:MGI:5005047 NCBI chrNW_004955413:29,360,125...29,379,196 JBrowse link
G Prr5l proline rich 5 like ISO (MGI:MGI:5005047|PMID:21413931) MGI PMID:21413931 MGI:MGI:5005047 NCBI chrNW_004955422:9,972,588...10,069,411 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (PMID:15166238) UniProtKB PMID:15166238 NCBI chrNW_004955461:14,337,914...14,622,779 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 ISO (PMID:19838216) BHF-UCL PMID:19838216 NCBI chrNW_004955413:4,525,954...4,547,177 JBrowse link
G Rara retinoic acid receptor alpha ISO PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chrNW_004955451:14,876,663...14,917,134 JBrowse link
G Reln reelin ISO (MGI:MGI:5286805|PMID:21664258) BHF-UCL PMID:21664258 MGI:MGI:5286805 NCBI chrNW_004955410:8,424,439...8,863,966 JBrowse link
G Rgl2 ral guanine nucleotide dissociation stimulator like 2 ISO (MGI:MGI:5547674|PMID:24069211) MGI PMID:24069211 MGI:MGI:5547674 NCBI chrNW_004955437:1,851,005...1,857,567 JBrowse link
G Selp selectin P ISO (PMID:17632516) UniProtKB PMID:17632516 NCBI chrNW_004955462:7,658,371...7,692,870 JBrowse link
G Sema4d semaphorin 4D ISO (PMID:16055703) UniProtKB PMID:16055703 NCBI chrNW_004955515:2,573,816...2,676,387 JBrowse link
G Serpina12 serpin family A member 12 ISO (MGI:MGI:5563627|PMID:22837305) MGI PMID:22837305 MGI:MGI:5563627 NCBI chrNW_004955438:17,826,596...17,849,341 JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:4821191|PMID:20620997) UniProtKB PMID:20620997 MGI:MGI:4821191 NCBI chrNW_004955425:20,280,725...20,307,663 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:MGI:4950303|PMID:21367821) UniProtKB PMID:21367821 MGI:MGI:4950303 NCBI chrNW_004955478:941,684...945,563 JBrowse link
G Tek TEK receptor tyrosine kinase ISO (PMID:12816861), (PMID:18425120), (PMID:19223473) UniProtKB PMID:12816861, PMID:18425120, PMID:19223473 NCBI chrNW_004955472:7,633,790...7,748,130 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (PMID:18223299) BHF-UCL PMID:18223299 NCBI chrNW_004955406:174,949...249,248 JBrowse link
G Tnf tumor necrosis factor ISO PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chrNW_004955437:117,267...119,899 JBrowse link
G Ube3a ubiquitin protein ligase E3A ISO (MGI:MGI:3616918|PMID:16254014) MGI PMID:16254014 MGI:MGI:3616918 NCBI chrNW_004955533:3,733,148...3,828,353 JBrowse link
G Unc5b unc-5 netrin receptor B ISO (PMID:18469807) UniProtKB PMID:18469807 NCBI chrNW_004955437:20,120,996...20,199,877 JBrowse link
G Wnt16 Wnt family member 16 ISO (PMID:19951988) BHF-UCL PMID:19951988 NCBI chrNW_004955479:3,065,312...3,077,260 JBrowse link
regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO PMID:11694516 UniProt PMID:11694516 RGD:11041061 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Crnn cornulin ISO (PMID:30009832) UniProt PMID:30009832 NCBI chrNW_004955589:47,743...75,383 JBrowse link
G Dipk2a divergent protein kinase domain 2A ISO (PMID:23784961) UniProtKB PMID:23784961 NCBI chrNW_004955508:1,954,600...1,975,842 JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004955456:321,222...456,431 JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) ISO (MGI:MGI:4881347|PMID:21074248) UniProtKB PMID:21074248 MGI:MGI:4881347 NCBI chrNW_004955523:1,407,812...1,441,829 JBrowse link
G Fbxl2 F-box and leucine rich repeat protein 2 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004955421:512,197...617,524 JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 ISO (MGI:MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:MGI:3769059 NCBI chrNW_004955528:490,319...492,943 JBrowse link
G Ppp1r16b protein phosphatase 1 regulatory subunit 16B ISO (PMID:25007873) GO_Central PMID:25007873 NCBI chrNW_004955445:17,864,103...17,961,295 JBrowse link
G Ptpn13 protein tyrosine phosphatase non-receptor type 13 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004955474:2,988,109...3,140,520 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO (MGI:MGI:3758152|PMID:17190838) MGI PMID:17190838 MGI:MGI:3758152 NCBI chrNW_004955416:5,494,030...5,561,608 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 11857
    signaling 4138
      signal transduction 3673
        intracellular signal transduction 1974
          inositol lipid-mediated signaling 138
            phosphatidylinositol-mediated signaling 136
              phosphatidylinositol 3-kinase signaling 115
                negative regulation of phosphatidylinositol 3-kinase signaling 15
                positive regulation of phosphatidylinositol 3-kinase signaling 63
                regulation of phosphatidylinositol 3-kinase signaling + 88
Path 2
Term Annotations click to browse term
  biological_process 11857
    biological regulation 8688
      regulation of biological process 8250
        regulation of cellular process 7832
          signal transduction 3673
            intracellular signal transduction 1974
              inositol lipid-mediated signaling 138
                phosphatidylinositol-mediated signaling 136
                  phosphatidylinositol 3-kinase signaling 115
                    negative regulation of phosphatidylinositol 3-kinase signaling 15
                    positive regulation of phosphatidylinositol 3-kinase signaling 63
                    regulation of phosphatidylinositol 3-kinase signaling + 88
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.