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ONTOLOGY REPORT - ANNOTATIONS


Term:phosphatidylinositol 3-kinase signaling
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Accession:GO:0014065 term browser browse the term
Definition:A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
Synonyms:exact_synonym: PI 3-kinase cascade;   PI3K cascade;   PI3K signal transduction;   PI3K signaling;   phosphatidylinositol 3-kinase signal transduction;   phosphoinositide 3-kinase cascade
 related_synonym: phosphatidylinositol 3-kinase cascade


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phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G C1qbp complement C1q binding protein ISO (PMID:16177118) UniProtKB PMID:16177118 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Cd160 CD160 molecule ISO (PMID:17307798) UniProt PMID:17307798 NCBI chrNW_004936867:478,625...485,905 JBrowse link
G Csf2 colony stimulating factor 2 ISO (PMID:24520418) AgBase PMID:24520418 NCBI chrNW_004936647:3,081,896...3,083,864 JBrowse link
G Edn1 endothelin 1 ISO (PMID:17078114) BHF-UCL PMID:17078114 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO (PMID:7556068) BHF-UCL PMID:7556068 NCBI chrNW_004936646:497,783...515,247 JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:MGI:5285154|PMID:20696860) UniProtKB PMID:20696860 MGI:MGI:5285154 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO (PMID:16517693) UniProtKB PMID:16517693 NCBI chrNW_004936565:335,238...394,683 JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B ISO (PMID:16517693) UniProtKB PMID:16517693 NCBI chrNW_004936525:5,711,894...5,729,074 JBrowse link
G Igf1 insulin like growth factor 1 ISO (PMID:24508636) AgBase PMID:24508636 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Irs1 insulin receptor substrate 1 ISO (PMID:7782332) BHF-UCL PMID:7782332 NCBI chrNW_004936525:9,064,442...9,125,972 JBrowse link
G Kbtbd2 kelch repeat and BTB domain containing 2 ISO (MGI:MGI:5806303|PMID:27708159) MGI PMID:27708159 MGI:MGI:5806303 NCBI chrNW_004936478:8,636,923...8,663,152 JBrowse link
G Ltk leukocyte receptor tyrosine kinase ISO (PMID:9223670) UniProtKB PMID:9223670 NCBI chrNW_004936471:4,849,261...4,857,892 JBrowse link
G Myo16 myosin XVI ISO (MGI:MGI:5304984|PMID:21946561) UniProtKB PMID:21946561 MGI:MGI:5304984 NCBI chrNW_004936472:3,157,508...3,548,164 JBrowse link
G Nf1 neurofibromin 1 ISO (MGI:MGI:3032882|PMID:14724565) MGI PMID:14724565 MGI:MGI:3032882 NCBI chrNW_004936538:3,394,623...3,596,025 JBrowse link
G Nyap1 neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 ISO (MGI:MGI:5304984|PMID:21946561) UniProtKB PMID:21946561 MGI:MGI:5304984 NCBI chrNW_004936543:552,688...561,192 JBrowse link
G Nyap2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 ISO (MGI:MGI:5304984|PMID:21946561) UniProtKB PMID:21946561 MGI:MGI:5304984 NCBI chrNW_004936525:9,986,669...10,234,653 JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 ISO (MGI:MGI:5817200|PMID:27614188) MGI PMID:27614188 MGI:MGI:5817200 NCBI chrNW_004936580:6,030,426...6,052,330 JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta ISO (PMID:25339672) CAFA PMID:25339672 NCBI chrNW_004936540:907,118...1,041,814 JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta ISO (PMID:25339672) CAFA PMID:25339672 NCBI chrNW_004936623:3,672,201...3,696,959 JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO (PMID:12507995) UniProtKB PMID:12507995 NCBI chrNW_004936479:17,084,006...17,112,264 JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO (PMID:7782332)
(PMID:21321938)
BHF-UCL PMID:7782332, PMID:21321938 NCBI chrNW_004936480:1,188,408...1,273,210 JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004936596:3,010,526...3,021,848 JBrowse link
G Pik3r5 phosphoinositide-3-kinase regulatory subunit 5 ISO (PMID:12507995) UniProt PMID:12507995 NCBI chrNW_004936595:2,029,074...2,053,954 JBrowse link
G Plekha1 pleckstrin homology domain containing A1 ISO (PMID:12101241) UniProtKB PMID:12101241 NCBI chrNW_004936486:11,203,873...11,241,028 JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 ISO (MGI:MGI:5550173|PMID:24367090) MGI PMID:24367090 MGI:MGI:5550173 NCBI chrNW_004936496:6,005,410...6,284,332 JBrowse link
G Sirt2 sirtuin 2 ISO (PMID:23908241) UniProtKB PMID:23908241 NCBI chrNW_004936661:1,828,868...1,849,892 JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:3050929|PMID:15249583) MGI PMID:15249583 MGI:MGI:3050929 NCBI chrNW_004936694:1,958,152...1,993,373 JBrowse link
G Xbp1 X-box binding protein 1 ISO (PMID:23529610) UniProtKB PMID:23529610 NCBI chrNW_004936657:2,891,171...2,895,409 JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 ISO (PMID:15538381) UniProtKB PMID:15538381 NCBI chrNW_004936495:12,045,679...12,050,737 JBrowse link
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cryba1 crystallin beta A1 ISO RGD PMID:21993393 RGD:10059647 NCBI chrNW_004936538:5,392,159...5,400,583 JBrowse link
G Dab2ip DAB2 interacting protein ISO (PMID:19903888) UniProtKB PMID:19903888 NCBI chrNW_004936487:10,056,809...10,243,021 JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E ISO RGD PMID:21436142 RGD:12911213 NCBI chrNW_004936669:1,377,005...1,385,287 JBrowse link
G Klf4 Kruppel like factor 4 ISO PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chrNW_004936559:5,105,456...5,109,970 JBrowse link
G LOC101962737 obscurin ISO (MGI:MGI:6101642|PMID:28826662) UniProt PMID:28826662 MGI:MGI:6101642 NCBI chrNW_004936864:619...33,574 JBrowse link
G Ncor1 nuclear receptor corepressor 1 ISO (MGI:MGI:3723397|PMID:17606624) MGI PMID:17606624 MGI:MGI:3723397 NCBI chrNW_004936821:382,756...538,254 JBrowse link
G Nlrc3 NLR family CARD domain containing 3 ISO (MGI:MGI:5883388|PMID:27951586) UniProtKB PMID:27951586 MGI:MGI:5883388 NCBI chrNW_004936694:757,121...773,924 JBrowse link
G Nop53 NOP53 ribosome biogenesis factor ISO (PMID:16971513) UniProtKB PMID:16971513 NCBI chrNW_004936664:1,334,487...1,343,867 JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 ISO (PMID:17475214)
(MGI:MGI:3806716|PMID:18632611)
UniProtKB PMID:17475214, PMID:18632611 MGI:MGI:3806716 NCBI chrNW_004936755:444,264...456,071 JBrowse link
G Serpine2 serpin family E member 2 ISO (MGI:MGI:3810206|PMID:18398001) MGI PMID:18398001 MGI:MGI:3810206 NCBI chrNW_004936569:5,642,328...5,668,278 JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 ISO (MGI:MGI:3617099|PMID:16456542) UniProtKB
MGI
PMID:16456542 MGI:MGI:3617099 NCBI chrNW_004936594:119,808...136,620 JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 ISO (MGI:MGI:3617099|PMID:16456542) MGI PMID:16456542 MGI:MGI:3617099 NCBI chrNW_004936694:2,000,977...2,006,102 JBrowse link
G Stambp STAM binding protein ISO (PMID:23542699) UniProtKB PMID:23542699 NCBI chrNW_004936556:143,483...174,383 JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:3586939|PMID:16027169) MGI PMID:16027169 MGI:MGI:3586939 NCBI chrNW_004936694:1,958,152...1,993,373 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17003487) BHF-UCL PMID:17003487 NCBI chrNW_004936546:5,331,220...5,332,669 JBrowse link
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 ISO PMID:18469807
PMID:14528310
UniProt PMID:14528310, PMID:18469807 RGD:1299350, RGD:8553892 NCBI chrNW_004936646:1,865,154...1,881,614 JBrowse link
G Agt angiotensinogen ISO (PMID:15652490) BHF-UCL PMID:15652490 NCBI chrNW_004936484:19,713,299...19,721,144 JBrowse link
G Angpt1 angiopoietin 1 ISO (MGI:MGI:3848848|PMID:19409199) MGI PMID:19409199 MGI:MGI:3848848 NCBI chrNW_004936470:37,105,469...37,328,183 JBrowse link
G Cat catalase ISO (MGI:MGI:3037350|PMID:15020231) MGI PMID:15020231 MGI:MGI:3037350 NCBI chrNW_004936533:3,601,270...3,637,128 JBrowse link
G Cbl Cbl proto-oncogene ISO (PMID:17003487) BHF-UCL PMID:17003487 NCBI chrNW_004936542:4,136,389...4,235,746 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO (PMID:7544376)
PMID:10477596
BHF-UCL PMID:7544376, PMID:10477596 RGD:8553666 NCBI chrNW_004936490:253,279...259,947 JBrowse link
G Cd28 CD28 molecule ISO (MGI:MGI:5520006|PMID:23589618) MGI PMID:23589618 MGI:MGI:5520006 NCBI chrNW_004936631:335,411...363,407 JBrowse link
G Cntf ciliary neurotrophic factor ISO RGD PMID:15574731 RGD:1626128 NCBI chrNW_004936581:3,710,171...3,715,753 JBrowse link
G Csf3 colony stimulating factor 3 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004936490:15,142,526...15,146,375 JBrowse link
G Dcn decorin ISO (PMID:23798385) MGI PMID:23798385 NCBI chrNW_004936507:7,887,259...7,923,055 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:16168116 RGD:1582137 NCBI chrNW_004936490:14,887,062...14,910,038 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO (MGI:MGI:3796800|PMID:18458158) MGI PMID:18458158 MGI:MGI:3796800 NCBI chrNW_004936586:4,065,767...5,100,690 JBrowse link
G F2 coagulation factor II, thrombin ISO (MGI:MGI:3810206|PMID:18398001) MGI PMID:18398001 MGI:MGI:3810206 NCBI chrNW_004936562:2,371,725...2,388,617 JBrowse link
G F2r coagulation factor II thrombin receptor ISO (MGI:MGI:5285163|PMID:20215560)
(MGI:MGI:3810206|PMID:18398001)
UniProtKB
MGI
PMID:18398001, PMID:20215560 MGI:MGI:3810206, MGI:MGI:5285163 NCBI chrNW_004936549:226,508...247,024 JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO (MGI:MGI:5285163|PMID:20215560) UniProtKB PMID:20215560 MGI:MGI:5285163 NCBI chrNW_004936549:142,281...153,575 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO (PMID:10739672) UniProtKB PMID:10739672 NCBI chrNW_004936474:11,897,998...11,919,153 JBrowse link
G Flt1 fms related receptor tyrosine kinase 1 ISO (PMID:14633857) UniProtKB PMID:14633857 NCBI chrNW_004936472:23,442,946...23,617,523 JBrowse link
G Fshr follicle stimulating hormone receptor ISO (PMID:24058690) UniProtKB PMID:24058690 NCBI chrNW_004936508:3,601,205...3,754,234 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chrNW_004936679:388,500...588,518 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ISO (PMID:15705806) UniProtKB
RGD
PMID:15705806, PMID:19717735 RGD:4892081 NCBI chrNW_004936754:1,288,891...1,293,555 JBrowse link
G Hax1 HCLS1 associated protein X-1 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004936580:3,961,433...3,964,322 JBrowse link
G Hcls1 hematopoietic cell-specific Lyn substrate 1 ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chrNW_004936536:8,065,489...8,084,777 JBrowse link
G Hcst hematopoietic cell signal transducer ISO (PMID:10426994) UniProtKB PMID:10426994 NCBI chrNW_004936570:460,890...462,354 JBrowse link
G Hgf hepatocyte growth factor ISO (PMID:20655899) BHF-UCL PMID:20655899 NCBI chrNW_004936734:354,798...428,356 JBrowse link
G Igf1 insulin like growth factor 1 ISO (MGI:MGI:5005047|PMID:21413931)
PMID:17023532
(PMID:7688386)
MGI
BHF-UCL
PMID:7688386, PMID:17023532, PMID:21413931 MGI:MGI:5005047, RGD:1600072 NCBI chrNW_004936492:11,709,623...11,784,028 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO RGD PMID:25186839 RGD:10046020 NCBI chrNW_004936483:4,563,995...4,860,231 JBrowse link
G Il18 interleukin 18 ISO (PMID:21321938) BHF-UCL PMID:21321938 NCBI chrNW_004936612:2,306,963...2,325,086 JBrowse link
G Ins insulin ISO (PMID:7688386) BHF-UCL PMID:7688386 NCBI chrNW_004936816:1,002,137...1,003,357 JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:MGI:3828423|PMID:7782332) BHF-UCL PMID:7782332 MGI:MGI:3828423 NCBI chrNW_004936503:111,722...243,627 JBrowse link
G Kdr kinase insert domain receptor ISO (PMID:9804796) UniProtKB
RGD
PMID:9804796, PMID:18221855 RGD:2292019 NCBI chrNW_004936482:17,537,697...17,581,320 JBrowse link
G Lep leptin ISO (MGI:MGI:4821191|PMID:20620997)
PMID:11677594
(PMID:24340098)
UniProtKB
UniProt
PMID:11677594, PMID:20620997, PMID:24340098 MGI:MGI:4821191, RGD:10448951 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G LOC101969021 somatotropin ISO (PMID:7782332) BHF-UCL PMID:7782332 NCBI chrNW_004936541:4,524,397...4,528,234 JBrowse link
G LOC101973578 adenosine receptor A3 ISO (MGI:MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:MGI:2664591 NCBI chrNW_004936690:152,777...168,411 JBrowse link
G LOC101975744 semaphorin-4D ISO (PMID:16055703) UniProtKB PMID:16055703 NCBI chrNW_004936780:317,926...350,113 JBrowse link
G Maz MYC associated zinc finger protein ISO (PMID:25487955) ARUK-UCL PMID:25487955 NCBI chrNW_004936501:12,664,861...12,668,819 JBrowse link
G Mydgf myeloid derived growth factor ISO (MGI:MGI:5609664|PMID:25581518) UniProtKB PMID:25581518 MGI:MGI:5609664 NCBI chrNW_004936588:2,706,329...2,716,545 JBrowse link
G Myoc myocilin ISO (PMID:21656515) UniProtKB PMID:21656515 NCBI chrNW_004936481:15,544,733...15,556,813 JBrowse link
G Ncf1 neutrophil cytosolic factor 1 ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004936543:3,617,369...3,630,990 JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO (PMID:17218260) BHF-UCL PMID:17218260 NCBI chrNW_004936471:17,254,777...17,374,725 JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO (PMID:20395202) UniProtKB PMID:20395202 NCBI chrNW_004936555:7,087,677...7,091,334 JBrowse link
G Nrg1 neuregulin 1 ISO (MGI:MGI:3796800|PMID:18458158) MGI PMID:18458158 MGI:MGI:3796800 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO PMID:10985347 UniProt PMID:10985347 RGD:8553408 NCBI chrNW_004936680:267,850...621,467 JBrowse link
G Osm oncostatin M ISO (PMID:28972028) BHF-UCL PMID:28972028 NCBI chrNW_004936904:390,089...394,195 JBrowse link
G Pdgfa platelet derived growth factor subunit A ISO (PMID:11788434) UniProtKB PMID:11788434 NCBI chrNW_004936754:808,894...828,554 JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO (PMID:10734101), (PMID:11788434), (PMID:17942966)
(MGI:MGI:3617099|PMID:16456542)
UniProtKB
MGI
PMID:10734101, PMID:11788434, PMID:16456542, PMID:17942966 MGI:MGI:3617099 NCBI chrNW_004936492:2,353,840...2,368,573 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO (MGI:MGI:5009390|PMID:17942966) UniProtKB PMID:17942966 MGI:MGI:5009390 NCBI chrNW_004936504:4,762,251...4,799,789 JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO (MGI:MGI:5305503|PMID:22187460), (MGI:MGI:5305504|PMID:22187458) UniProtKB PMID:22187458, PMID:22187460 MGI:MGI:5305503, MGI:MGI:5305504 NCBI chrNW_004936636:2,822,100...2,935,252 JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:15705590 RGD:2299907 NCBI chrNW_004936677:2,870,664...2,883,545 JBrowse link
G Plxnb1 plexin B1 ISO (MGI:MGI:4413657|PMID:19788569) UniProtKB PMID:19788569 MGI:MGI:4413657 NCBI chrNW_004936529:197,834...226,064 JBrowse link
G Prr5 proline rich 5 ISO (MGI:MGI:5005047|PMID:21413931) MGI PMID:21413931 MGI:MGI:5005047 NCBI chrNW_004936718:2,094,802...2,170,916 JBrowse link
G Prr5l proline rich 5 like ISO (MGI:MGI:5005047|PMID:21413931) MGI PMID:21413931 MGI:MGI:5005047 NCBI chrNW_004936533:1,895,594...1,975,442 JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO (PMID:15166238) UniProtKB PMID:15166238 NCBI chrNW_004936470:10,379,855...10,578,531 JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 ISO (PMID:19838216) BHF-UCL PMID:19838216 NCBI chrNW_004936709:864,206...884,630 JBrowse link
G Rara retinoic acid receptor alpha ISO PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chrNW_004936490:15,376,217...15,420,638 JBrowse link
G Reln reelin ISO (MGI:MGI:5286805|PMID:21664258) BHF-UCL PMID:21664258 MGI:MGI:5286805 NCBI chrNW_004936479:19,628,488...20,088,278 JBrowse link
G Rgl2 ral guanine nucleotide dissociation stimulator like 2 ISO (MGI:MGI:5547674|PMID:24069211) MGI PMID:24069211 MGI:MGI:5547674 NCBI chrNW_004936476:25,566,714...25,574,667 JBrowse link
G Selp selectin P ISO (PMID:17632516) UniProtKB PMID:17632516 NCBI chrNW_004936481:17,076,660...17,112,501 JBrowse link
G Sirt1 sirtuin 1 ISO (MGI:MGI:4821191|PMID:20620997) UniProtKB PMID:20620997 MGI:MGI:4821191 NCBI chrNW_004936521:10,296,097...10,316,673 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (MGI:MGI:4950303|PMID:21367821) UniProtKB PMID:21367821 MGI:MGI:4950303 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Tek TEK receptor tyrosine kinase ISO (PMID:12816861), (PMID:18425120), (PMID:19223473) UniProtKB PMID:12816861, PMID:18425120, PMID:19223473 NCBI chrNW_004936611:2,420,176...2,531,726 JBrowse link
G Tgfb2 transforming growth factor beta 2 ISO (PMID:18223299) BHF-UCL PMID:18223299 NCBI chrNW_004936628:310,720...394,002 JBrowse link
G Tnf tumor necrosis factor ISO PMID:12729461 ARUK-UCL PMID:12729461 RGD:13673777 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
G Ube3a ubiquitin protein ligase E3A ISO (MGI:MGI:3616918|PMID:16254014) MGI PMID:16254014 MGI:MGI:3616918 NCBI chrNW_004936471:41,187,665...41,290,345 JBrowse link
G Unc5b unc-5 netrin receptor B ISO (PMID:18469807) UniProtKB PMID:18469807 NCBI chrNW_004936521:7,472,788...7,547,408 JBrowse link
G Wnt16 Wnt family member 16 ISO (PMID:19951988) BHF-UCL PMID:19951988 NCBI chrNW_004936605:3,855,640...3,867,166 JBrowse link
regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO PMID:11694516 UniProt PMID:11694516 RGD:11041061 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G Dipk2a divergent protein kinase domain 2A ISO (PMID:23784961) UniProtKB PMID:23784961 NCBI chrNW_004936519:10,966,822...10,988,311 JBrowse link
G Egfr epidermal growth factor receptor ISO (PMID:26514923) CAFA PMID:26514923 NCBI chrNW_004936678:365,005...560,546 JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) ISO (MGI:MGI:4881347|PMID:21074248) UniProtKB PMID:21074248 MGI:MGI:4881347 NCBI chrNW_004936488:3,241,004...3,280,360 JBrowse link
G Fbxl2 F-box and leucine rich repeat protein 2 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004936473:23,567,251...23,659,708 JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 ISO (MGI:MGI:3769059|PMID:16249387) MGI PMID:16249387 MGI:MGI:3769059 NCBI chrNW_004936514:10,980,136...10,983,323 JBrowse link
G Ppp1r16b protein phosphatase 1 regulatory subunit 16B ISO (PMID:25007873) GO_Central PMID:25007873 NCBI chrNW_004936561:2,552,168...2,654,085 JBrowse link
G Ptpn13 protein tyrosine phosphatase non-receptor type 13 ISO (PMID:23604317) UniProtKB PMID:23604317 NCBI chrNW_004936920:313,762...510,334 JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO (MGI:MGI:3758152|PMID:17190838) MGI PMID:17190838 MGI:MGI:3758152 NCBI chrNW_004936471:2,152,231...2,222,260 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11962
    signaling 4166
      signal transduction 3695
        intracellular signal transduction 1982
          inositol lipid-mediated signaling 139
            phosphatidylinositol-mediated signaling 137
              phosphatidylinositol 3-kinase signaling 117
                negative regulation of phosphatidylinositol 3-kinase signaling 15
                positive regulation of phosphatidylinositol 3-kinase signaling 65
                regulation of phosphatidylinositol 3-kinase signaling + 89
Path 2
Term Annotations click to browse term
  biological_process 11962
    biological regulation 8755
      regulation of biological process 8316
        regulation of cellular process 7896
          signal transduction 3695
            intracellular signal transduction 1982
              inositol lipid-mediated signaling 139
                phosphatidylinositol-mediated signaling 137
                  phosphatidylinositol 3-kinase signaling 117
                    negative regulation of phosphatidylinositol 3-kinase signaling 15
                    positive regulation of phosphatidylinositol 3-kinase signaling 65
                    regulation of phosphatidylinositol 3-kinase signaling + 89
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.