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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
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Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


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regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:11041061
G Cep55 centrosomal protein 55 JBrowse link 1 256,745,251 256,760,794 RGD:1600115
G Crnn cornulin JBrowse link 2 193,427,097 193,432,070 RGD:1624291
G Dipk2a divergent protein kinase domain 2A JBrowse link 8 102,140,713 102,159,828 RGD:1624291
RGD:13792537
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 JBrowse link 6 108,087,677 108,123,811 RGD:1624291
RGD:1600115
G Fbxl2 F-box and leucine-rich repeat protein 2 JBrowse link 8 122,240,393 122,290,439 RGD:1624291
G Lime1 Lck interacting transmembrane adaptor 1 JBrowse link 3 176,881,881 176,888,230 RGD:1624291
RGD:13792537
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B JBrowse link 3 155,160,474 155,267,002 RGD:1624291
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 JBrowse link 14 7,688,551 7,863,664 RGD:1624291
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 17 43,867,243 43,878,734 RGD:1624291
G Cryba1 crystallin, beta A1 JBrowse link 10 65,160,777 65,167,504 RGD:10059647
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Inpp5e inositol polyphosphate-5-phosphatase E JBrowse link 3 3,843,307 3,856,154 RGD:12911213
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:8553301
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 10 11,809,531 11,844,184 RGD:1624291
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 1 77,836,522 77,843,991 RGD:1624291
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 10 45,353,185 45,483,570 RGD:1624291
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 14 83,559,397 83,572,481 RGD:1600115
RGD:1624291
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1624291
RGD:1600115
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
RGD:1600115
G Slc9a3r2 SLC9A3 regulator 2 JBrowse link 10 14,003,330 14,015,066 RGD:1624291
G Stambp Stam binding protein JBrowse link 4 115,249,343 115,277,340 RGD:1624291
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:1624291
G Twist1 twist family bHLH transcription factor 1 JBrowse link 6 53,401,241 53,403,235 RGD:1624291
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 7 70,360,199 70,377,422 RGD:1299350
RGD:8553892
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1624291
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1624291
RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1624291
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:1624291
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
RGD:8553666
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cntf ciliary neurotrophic factor JBrowse link 1 229,599,009 229,601,032 RGD:1626128
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:1624291
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:1624291
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:1582137
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:1624291
RGD:1600115
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1624291
RGD:1600115
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1600115
RGD:1624291
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Fgr FGR proto-oncogene, Src family tyrosine kinase JBrowse link 5 151,172,189 151,199,746 RGD:1624291
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:1600115
RGD:1624291
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:14695080
G Fshr follicle stimulating hormone receptor JBrowse link 6 12,796,383 12,997,817 RGD:1624291
RGD:1600115
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:8553892
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:4892081
RGD:1624291
RGD:1600115
G Hax1 HCLS1 associated protein X-1 JBrowse link 2 189,330,900 189,333,305 RGD:1624291
RGD:1600115
G Hcls1 hematopoietic cell specific Lyn substrate 1 JBrowse link 11 66,736,966 66,759,402 RGD:1624291
G Hcst hematopoietic cell signal transducer JBrowse link 1 88,879,425 88,881,653 RGD:1624291
RGD:13792537
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1624291
RGD:1600115
RGD:1600072
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:10046020
RGD:13792537
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1600115
RGD:1624291
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:1624291
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:13792537
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:2292019
RGD:1600115
RGD:1624291
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:10448951
RGD:13792537
RGD:1624291
G LOC103694380 tumor necrosis factor-like JBrowse link 20 4,855,792 4,858,447 RGD:13673777
G Maz MYC associated zinc finger protein JBrowse link 1 198,456,699 198,460,126 RGD:1624291
G Mydgf myeloid-derived growth factor JBrowse link 9 10,885,521 10,892,744 RGD:1624291
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:1600115
RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:1624291
RGD:1600115
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:1624291
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:13792537
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:8553408
RGD:13792537
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 139,890,537 140,262,503 RGD:13792537
G Osm oncostatin M JBrowse link 14 84,457,487 84,469,426 RGD:1624291
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:1600115
RGD:13792537
RGD:1624291
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1624291
RGD:13792537
RGD:1600115
G Pdgfc platelet derived growth factor C JBrowse link 2 179,952,227 180,126,897 RGD:13792537
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:13792537
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:1624291
RGD:1600115
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 1 260,527,344 260,679,132 RGD:1624291
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:2299907
G Plxnb1 plexin B1 JBrowse link 8 117,832,826 117,858,515 RGD:1624291
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:1624291
G Prr5 proline rich 5 JBrowse link 7 125,569,791 125,609,340 RGD:1624291
RGD:1600115
G Prr5l proline rich 5 like JBrowse link 3 91,290,207 91,461,208 RGD:1624291
RGD:1600115
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:1600115
RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:8553301
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 JBrowse link 20 5,458,509 5,466,853 RGD:1624291
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 5 118,892,874 119,239,528 RGD:13792537
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 17 11,953,552 12,134,386 RGD:13792537
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:1600115
RGD:1624291
G Sema4d semaphorin 4D JBrowse link 17 13,516,276 13,538,513 RGD:1624291
G Serpina12 serpin family A member 12 JBrowse link 6 127,696,501 127,711,238 RGD:1624291
RGD:1600115
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tek TEK receptor tyrosine kinase JBrowse link 5 113,725,717 113,852,799 RGD:1624291
RGD:13792537
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:13673777
G Ube3a ubiquitin protein ligase E3A JBrowse link 1 116,586,901 116,678,161 RGD:1624291
G Unc5b unc-5 netrin receptor B JBrowse link 20 30,339,680 30,406,593 RGD:1600115
RGD:1624291
G Wnt16 Wnt family member 16 JBrowse link 4 49,369,246 49,388,156 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    signaling 7531
      signal transduction 6946
        intracellular signal transduction 2594
          regulation of intracellular signal transduction 1694
            regulation of phosphatidylinositol 3-kinase signaling 103
              negative regulation of phosphatidylinositol 3-kinase signaling 16
              positive regulation of phosphatidylinositol 3-kinase signaling 76
Path 2
Term Annotations click to browse term
  biological_process 19678
    biological regulation 13599
      regulation of biological process 12921
        regulation of cellular process 12405
          signal transduction 6946
            intracellular signal transduction 2594
              inositol lipid-mediated signaling 178
                phosphatidylinositol-mediated signaling 175
                  phosphatidylinositol 3-kinase signaling 138
                    regulation of phosphatidylinositol 3-kinase signaling 103
                      negative regulation of phosphatidylinositol 3-kinase signaling 16
                      positive regulation of phosphatidylinositol 3-kinase signaling 76
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.