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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
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Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


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regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 39,395,550 39,417,063 RGD:9068941
G CRNN cornulin JBrowse link 1 127,743,094 127,748,737 RGD:9068941
G DIPK2A divergent protein kinase domain 2A JBrowse link 3 140,999,699 141,019,908 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 7 55,614,042 55,807,285 RGD:9068941
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) JBrowse link 14 54,522,428 54,578,501 RGD:9068941
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 3 33,199,436 33,308,831 RGD:9068941
G LIME1 Lck interacting transmembrane adaptor 1 RGD:9068941
G PPP1R16B protein phosphatase 1 regulatory subunit 16B JBrowse link 20 35,130,114 35,248,031 RGD:9068941
G PTPN13 protein tyrosine phosphatase non-receptor type 13 JBrowse link 4 78,893,598 79,118,745 RGD:9068941
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 15 17,417,684 17,494,333 RGD:9068941
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,215,215 26,227,261 RGD:9068941
G CRYBA1 crystallin beta A1 JBrowse link 17 27,522,647 27,530,767 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 92,696,798 92,912,425 RGD:9068941
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 107,502,838 107,516,325 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 9 78,634,545 78,639,447 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 34,934,452 35,121,195 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 16 2,463,940 2,487,961 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 44,739,739 44,751,303 RGD:9068941
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 1 203,605,558 203,781,491 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 22 12,305,518 12,316,434 RGD:9068941
G SERPINE2 serpin family E member 2 JBrowse link 2B 111,221,317 111,285,491 RGD:9068941
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 17 68,694,468 68,715,157 RGD:9068941
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 16 664,310 676,640 RGD:9068941
G STAMBP STAM binding protein JBrowse link 2A 73,900,128 73,936,571 RGD:9068941
G TSC2 TSC complex subunit 2 JBrowse link 16 615,776 655,411 RGD:9068941
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 7 19,761,041 19,765,665 RGD:9068941
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 12 31,187,821 31,201,594 RGD:9068941
G AGT angiotensinogen JBrowse link 1 206,252,141 206,263,830 RGD:9068941
G ANGPT1 angiopoietin 1 JBrowse link 8 103,893,234 104,137,661 RGD:9068941
G ARHGAP8 Rho GTPase activating protein 8 JBrowse link 22 25,650,927 25,755,578 RGD:9068941
G CAT catalase JBrowse link 11 34,413,253 34,446,831 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 11 114,044,996 114,149,204 RGD:9068941
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 20,915,198 20,923,530 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 90,938,795 90,971,438 RGD:9068941
G CNTF ciliary neurotrophic factor JBrowse link 11 53,876,081 53,882,870 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 17 17,271,074 17,273,493 RGD:9068941
G DCN decorin JBrowse link 12 88,678,791 88,715,677 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 17,560,337 17,600,808 RGD:9068941
G ERBB4 erb-b2 receptor tyrosine kinase 4 JBrowse link 2B 98,625,630 99,795,371 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link 11 46,669,925 46,690,391 RGD:9068941
G F2R coagulation factor II thrombin receptor JBrowse link 5 38,565,957 38,585,725 RGD:9068941
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 38,462,521 38,478,882 RGD:9068941
G FGR FGR proto-oncogene, Src family tyrosine kinase JBrowse link 1 26,872,781 26,895,751 RGD:9068941
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 13 9,584,850 9,779,542 RGD:9068941
G FPR2 formyl peptide receptor 2 JBrowse link 19 48,663,622 48,715,535 RGD:9068941
G FSHR follicle stimulating hormone receptor JBrowse link 2A 49,088,450 49,287,688 RGD:9068941
G FYN FYN proto-oncogene, Src family tyrosine kinase JBrowse link 6 109,469,750 109,684,086 RGD:9068941
G HAX1 HCLS1 associated protein X-1 JBrowse link 1 129,627,564 129,630,920 RGD:9068941
G HCLS1 hematopoietic cell-specific Lyn substrate 1 JBrowse link 3 118,733,505 118,763,177 RGD:9068941
G HCST hematopoietic cell signal transducer JBrowse link 19 32,817,826 32,821,149 RGD:9068941
G HGF hepatocyte growth factor JBrowse link 7 73,667,618 73,738,960 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 12 99,986,887 100,066,773 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 77,332,926 77,648,474 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 107,024,376 107,045,194 RGD:9068941
G INS insulin JBrowse link 11 2,200,785 2,202,579 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 4,820,303 4,971,867 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 4 68,813,894 68,861,018 RGD:9068941
G LEP leptin JBrowse link 7 120,230,896 120,248,602 RGD:9068941
G LOC100967334 G-protein coupled estrogen receptor 1 JBrowse link 7 1,245,873 1,251,915 RGD:9068941
G LOC100971425 somatotropin JBrowse link 17 58,010,848 58,013,421 RGD:9068941
G MAZ MYC associated zinc finger protein RGD:9068941
G MYDGF myeloid derived growth factor JBrowse link 19 3,674,001 3,689,123 RGD:9068941
G MYOC myocilin JBrowse link 1 147,128,541 147,146,227 RGD:9068941
G NCF1 neutrophil cytosolic factor 1 RGD:9068941
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 15 34,798,880 34,963,823 RGD:9068941
G NKX3-1 NK3 homeobox 1 JBrowse link 8 22,926,145 22,930,396 RGD:9068941
G NRG1 neuregulin 1 JBrowse link 8 30,954,852 32,084,411 RGD:9068941
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 39,663,986 40,208,770 RGD:9068941
G OSM oncostatin M JBrowse link 22 11,298,965 11,303,009 RGD:9068941
G PDGFA platelet derived growth factor subunit A JBrowse link 7 648,722 672,023 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 22 20,127,223 20,148,407 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 145,538,330 145,580,312 RGD:9068941
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 10 93,210,174 93,339,545 RGD:9068941
G PLD2 phospholipase D2 JBrowse link 17 4,853,919 4,870,254 RGD:9068941
G PLXNB1 plexin B1 JBrowse link 3 48,325,892 48,352,128 RGD:9068941
G PRR5L proline rich 5 like JBrowse link 11 36,269,291 36,438,954 RGD:9068941
G PTK2 protein tyrosine kinase 2 JBrowse link 8 137,330,777 137,677,306 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 7,075,879 7,093,041 RGD:9068941
G RARA retinoic acid receptor alpha JBrowse link 17 16,932,485 16,980,958 RGD:9068941
G RELN reelin JBrowse link 7 95,464,285 95,984,813 RGD:9068941
G RGL2 ral guanine nucleotide dissociation stimulator like 2 JBrowse link 6 32,863,954 32,871,684 RGD:9068941
G SELP selectin P JBrowse link 1 145,071,094 145,112,851 RGD:9068941
G SEMA4D semaphorin 4D JBrowse link 9 60,451,420 60,588,519 RGD:9068941
G SERPINA12 serpin family A member 12 JBrowse link 14 75,110,414 75,141,569 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 64,368,878 64,401,684 RGD:9068941
G SOX9 SRY-box transcription factor 9 JBrowse link 17 66,028,737 66,034,122 RGD:9068941
G TEK TEK receptor tyrosine kinase JBrowse link 9 26,955,339 27,077,809 RGD:9068941
G TGFB2 transforming growth factor beta 2 JBrowse link 1 193,907,398 194,005,800 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 31,236,650 31,239,423 RGD:9068941
G UBE3A ubiquitin protein ligase E3A JBrowse link 15 4,494,029 4,595,415 RGD:9068941
G UNC5B unc-5 netrin receptor B JBrowse link 10 67,682,415 67,772,760 RGD:9068941
G WNT16 Wnt family member 16 JBrowse link 7 113,338,322 113,354,002 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12490
    signaling 4282
      signal transduction 3790
        intracellular signal transduction 2033
          regulation of intracellular signal transduction 1483
            regulation of phosphatidylinositol 3-kinase signaling 92
              negative regulation of phosphatidylinositol 3-kinase signaling 16
              positive regulation of phosphatidylinositol 3-kinase signaling 66
Path 2
Term Annotations click to browse term
  biological_process 12490
    biological regulation 9101
      regulation of biological process 8628
        regulation of cellular process 8158
          signal transduction 3790
            intracellular signal transduction 2033
              inositol lipid-mediated signaling 141
                phosphatidylinositol-mediated signaling 139
                  phosphatidylinositol 3-kinase signaling 118
                    regulation of phosphatidylinositol 3-kinase signaling 92
                      negative regulation of phosphatidylinositol 3-kinase signaling 16
                      positive regulation of phosphatidylinositol 3-kinase signaling 66
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.