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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
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Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


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regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 1 111,902,429 111,919,191 RGD:9068941
G CEP55 centrosomal protein 55 JBrowse link 28 7,754,934 7,777,662 RGD:13508589
G CRNN cornulin JBrowse link 17 61,380,706 61,386,294 RGD:9068941
G DIPK2A divergent protein kinase domain 2A JBrowse link 23 39,472,090 39,496,000 RGD:13508589
G EGFR epidermal growth factor receptor JBrowse link 18 5,983,669 6,044,092 RGD:13508589
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) JBrowse link 8 47,193,463 47,245,865 RGD:9068941
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 23 3,498,253 3,606,016 RGD:9068941
G LIME1 Lck interacting transmembrane adaptor 1 JBrowse link 24 47,269,922 47,272,288 RGD:9068941
G PPP1R16B protein phosphatase 1 regulatory subunit 16B JBrowse link 24 27,206,870 27,299,956 RGD:13508589
G PTPN13 protein tyrosine phosphatase non-receptor type 13 JBrowse link 32 10,125,447 10,328,764 RGD:13508589
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 30 5,840,901 5,914,804 RGD:13508589
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CRYBA1 crystallin beta A1 JBrowse link 9 43,372,507 43,378,561 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 9 60,725,887 60,918,242 RGD:9068941
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 49,061,014 49,071,474 RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 11 62,881,840 62,886,676 RGD:9068941
G LOC100855640 butyrophilin subfamily 2 member A2 JBrowse link 35 24,251,221 24,265,040 RGD:13508589
G NCOR1 nuclear receptor corepressor 1 JBrowse link 5 39,687,530 39,837,003 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 6 37,668,654 37,707,387 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 1 108,307,039 108,315,732 RGD:13508589
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 14 664,404 782,376 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 26 24,243,195 24,255,335 RGD:13508589
G SERPINE2 serpin family E member 2 JBrowse link 37 29,699,551 29,750,151 RGD:13508589
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 9 5,661,792 5,679,783 RGD:13508589
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 6 38,905,070 38,915,028 RGD:9068941
G STAMBP STAM binding protein JBrowse link 17 49,194,810 49,221,017 RGD:13508589
G TSC2 TSC complex subunit 2 JBrowse link 6 38,865,509 38,898,977 RGD:9068941
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA3 adenosine A3 receptor JBrowse link 17 63,895,408 63,898,666 RGD:9068941
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 10 1,791,273 1,807,710 RGD:9068941
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:13508589
G ANGPT1 angiopoietin 1 JBrowse link 13 8,068,920 8,312,090 RGD:9068941
G CAT catalase JBrowse link 18 33,383,005 33,422,447 RGD:13508589
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:9068941
G CCL5 C-C motif chemokine ligand 5 JBrowse link 9 37,817,409 37,823,852 RGD:13508589
G CD28 CD28 molecule JBrowse link 37 12,503,849 12,536,362 RGD:9068941
G CNTF ciliary neurotrophic factor JBrowse link 18 37,758,148 37,765,698 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 9 22,529,643 22,532,326 RGD:13508589
G DCN decorin JBrowse link 15 31,833,492 31,887,699 RGD:13508589
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 9 22,760,373 22,785,367 RGD:9068941
G ERBB4 erb-b2 receptor tyrosine kinase 4 JBrowse link 37 19,029,647 20,134,576 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link 18 42,782,744 42,799,531 RGD:13508589
G F2R coagulation factor II thrombin receptor JBrowse link 3 29,870,159 29,889,837 RGD:13508589
G F2RL1 F2R like trypsin receptor 1 JBrowse link 3 29,801,119 29,810,006 RGD:13508589
G FGR FGR proto-oncogene, Src family tyrosine kinase JBrowse link 2 72,678,858 72,692,417 RGD:13508589
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 25 11,231,958 11,410,379 RGD:13508589
G FPR2 formyl peptide receptor 2 JBrowse link 1 105,343,096 105,353,563 RGD:9068941
G FSHR follicle stimulating hormone receptor JBrowse link 10 50,765,591 50,938,643 RGD:9068941
G FYN FYN proto-oncogene, Src family tyrosine kinase JBrowse link 12 68,105,060 68,316,630 RGD:9068941
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 6 15,792,072 15,796,922 RGD:13508589
G HAX1 HCLS1 associated protein X-1 JBrowse link 7 42,969,711 42,972,783 RGD:13508589
G HCLS1 hematopoietic cell-specific Lyn substrate 1 JBrowse link 33 24,901,023 24,925,710 RGD:13508589
G HCST hematopoietic cell signal transducer JBrowse link 1 116,760,605 116,763,355 RGD:13508589
G HGF hepatocyte growth factor JBrowse link 18 21,329,688 21,410,257 RGD:13508589
G IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:13508589
G IL18 interleukin 18 JBrowse link 5 20,972,742 20,995,327 RGD:13508589
G INS insulin JBrowse link 18 46,324,047 46,324,933 RGD:9068941
G INSR insulin receptor JBrowse link 20 52,017,261 52,136,061 RGD:13508589
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 13 47,442,861 47,484,574 RGD:13508589
G LEP leptin JBrowse link 14 8,115,396 8,130,946 RGD:13508589
G MAZ MYC associated zinc finger protein JBrowse link 6 17,867,491 17,870,108 RGD:9068941
G MYDGF myeloid derived growth factor JBrowse link 20 55,084,060 55,096,544 RGD:13508589
G MYOC myocilin JBrowse link 7 27,335,314 27,346,821 RGD:13508589
G NCF1 neutrophil cytosolic factor 1 JBrowse link 6 5,702,222 5,719,515 RGD:13508589
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 30 21,123,333 21,229,907 RGD:13508589
G NKX3-1 NK3 homeobox 1 JBrowse link 25 33,815,343 33,817,465 RGD:13508589
G NRG1 neuregulin 1 JBrowse link 16 31,697,958 32,771,888 RGD:9068941
G NTRK1 neurotrophic receptor tyrosine kinase 1 JBrowse link 7 41,140,931 41,159,326 RGD:13508589
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 1 74,447,927 74,777,910 RGD:13508589
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 3 51,131,470 51,491,112 RGD:13508589
G OSM oncostatin M JBrowse link 26 23,421,787 23,439,332 RGD:13508589
G PDGFA platelet derived growth factor subunit A JBrowse link 6 16,271,082 16,293,246 RGD:13508589
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:13508589
G PDGFC platelet derived growth factor C JBrowse link 15 54,143,637 54,239,962 RGD:13508589
G PDGFD platelet derived growth factor D JBrowse link 5 27,863,739 28,092,376 RGD:13508589
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:13508589
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 28 9,977,463 10,095,363 RGD:13508589
G PLD2 phospholipase D2 JBrowse link 5 31,755,881 31,767,131 RGD:9068941
G PLXNB1 plexin B1 JBrowse link 20 40,658,938 40,685,219 RGD:13508589
G PPARD peroxisome proliferator activated receptor delta JBrowse link 12 4,492,867 4,579,340 RGD:13508589
G PRR5 proline rich 5 JBrowse link 10 21,164,530 21,188,537 RGD:13508589
G PRR5L proline rich 5 like JBrowse link 18 31,708,888 31,849,365 RGD:9068941
G PTK2 protein tyrosine kinase 2 JBrowse link 13 35,302,439 35,541,336 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 27 38,084,976 38,101,552 RGD:9068941
G RARA retinoic acid receptor alpha JBrowse link 9 22,254,803 22,298,614 RGD:9068941
G RELN reelin JBrowse link 18 16,275,822 16,773,875 RGD:13508589
G RGL2 ral guanine nucleotide dissociation stimulator like 2 JBrowse link 12 2,731,366 2,739,141 RGD:9068941
G ROR1 receptor tyrosine kinase like orphan receptor 1 JBrowse link 5 46,010,097 46,477,882 RGD:13508589
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 1 95,209,122 95,280,956 RGD:13508589
G SELP selectin P JBrowse link 7 28,956,428 28,997,266 RGD:13508589
G SEMA4D semaphorin 4D JBrowse link 1 96,825,963 96,878,956 RGD:9068941
G SERPINA12 serpin family A member 12 JBrowse link 8 63,497,542 63,511,701 RGD:13508589
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SOX9 SRY-box transcription factor 9 JBrowse link 9 8,275,049 8,278,172 RGD:13508589
G TEK TEK receptor tyrosine kinase JBrowse link 11 45,278,375 45,377,300 RGD:13508589
G TGFB2 transforming growth factor beta 2 JBrowse link 38 13,430,832 13,511,655 RGD:13508589
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
G UBE3A ubiquitin protein ligase E3A JBrowse link 3 35,347,034 35,442,329 RGD:9068941
G UNC5B unc-5 netrin receptor B JBrowse link 4 22,003,131 22,084,107 RGD:9068941
G WNT16 Wnt family member 16 JBrowse link 14 59,388,034 59,404,812 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16042
    signaling 5937
      signal transduction 5381
        intracellular signal transduction 2458
          regulation of intracellular signal transduction 1615
            regulation of phosphatidylinositol 3-kinase signaling 100
              negative regulation of phosphatidylinositol 3-kinase signaling 15
              positive regulation of phosphatidylinositol 3-kinase signaling 74
Path 2
Term Annotations click to browse term
  biological_process 16042
    biological regulation 11411
      regulation of biological process 10830
        regulation of cellular process 10368
          signal transduction 5381
            intracellular signal transduction 2458
              inositol lipid-mediated signaling 171
                phosphatidylinositol-mediated signaling 168
                  phosphatidylinositol 3-kinase signaling 134
                    regulation of phosphatidylinositol 3-kinase signaling 100
                      negative regulation of phosphatidylinositol 3-kinase signaling 15
                      positive regulation of phosphatidylinositol 3-kinase signaling 74
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.