Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
go back to main search page
Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


show annotations for term's descendants       view all columns           Sort by:
 
regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AL121845.2 novel transcript, LIME1-SLC2A4RG readthrough RGD:2290271
G AL121845.3 novel protein, ZGPAT-LIME1 readthrough RGD:2290271
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 42,507,306 42,528,482 RGD:2290271
G CEP55 centrosomal protein 55 JBrowse link 10 93,496,612 93,529,094 RGD:2290271
G CRNN cornulin JBrowse link 1 152,409,243 152,414,263 RGD:2290271
G DIPK2A divergent protein kinase domain 2A JBrowse link 3 143,971,798 143,992,368 RGD:2290271
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:2290271
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) JBrowse link 14 73,955,329 74,019,326 RGD:2290271
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 3 33,277,025 33,422,698 RGD:2290271
G IER3 immediate early response 3 JBrowse link 6 30,743,199 30,744,547 RGD:2290271
G LIME1 Lck interacting transmembrane adaptor 1 JBrowse link 20 63,735,701 63,739,107 RGD:2290271
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:2290271
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:2290271
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha JBrowse link 10 22,534,837 22,714,578 RGD:2290271
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta JBrowse link 17 38,765,691 38,799,905 RGD:2290271
G PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma JBrowse link 12 57,591,188 57,603,418 RGD:2290271
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha JBrowse link 1 151,197,954 151,249,536 RGD:2290271
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta JBrowse link 9 68,705,240 69,009,176 RGD:2290271
G PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma JBrowse link 19 3,630,181 3,700,486 RGD:2290271
G PPP1R16B protein phosphatase 1 regulatory subunit 16B JBrowse link 20 38,805,694 38,923,024 RGD:2290271
G PPP2R5B protein phosphatase 2 regulatory subunit B'beta JBrowse link 11 64,917,553 64,934,478 RGD:2290271
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma JBrowse link 14 101,760,573 101,927,992 RGD:2290271
G PTPN13 protein tyrosine phosphatase non-receptor type 13 JBrowse link 4 86,594,307 86,815,176 RGD:2290271
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 15 38,488,097 38,564,814 RGD:2290271
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 6 26,382,893 26,394,874 RGD:2290271
G CRYBA1 crystallin beta A1 JBrowse link 17 29,246,859 29,254,494 RGD:2290271
G DAB2IP DAB2 interacting protein JBrowse link 9 121,566,883 121,785,530 RGD:2290271
G INPP5E inositol polyphosphate-5-phosphatase E JBrowse link 9 136,428,619 136,439,861 RGD:2290271
G KLF4 Kruppel like factor 4 JBrowse link 9 107,484,852 107,489,769 RGD:2290271
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 16,029,157 16,216,475 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 16 3,539,033 3,577,782 RGD:2290271
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 19 47,745,546 47,757,058 RGD:2290271
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 1 228,208,044 228,378,874 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 22 31,281,593 31,292,534 RGD:2290271
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,625 87,971,930 RGD:2290271
G SERPINE2 serpin family E member 2 JBrowse link 2 223,975,045 224,039,319 RGD:2290271
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 17 74,748,628 74,769,353 RGD:2290271
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 16 2,026,902 2,039,026 RGD:9068941
G STAMBP STAM binding protein JBrowse link 2 73,828,911 73,873,656 RGD:2290271
G TSC2 TSC complex subunit 2 JBrowse link 16 2,047,804 2,089,491 RGD:2290271
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 7 19,113,047 19,117,636 RGD:2290271
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA3 adenosine A3 receptor JBrowse link 1 111,499,429 111,503,633 RGD:9068941
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 12 57,723,761 57,742,201 RGD:2290271
G AGT angiotensinogen JBrowse link 1 230,702,523 230,745,583 RGD:2290271
G ANGPT1 angiopoietin 1 JBrowse link 8 107,249,482 107,497,918 RGD:2290271
G BECN1 beclin 1 JBrowse link 17 42,810,132 42,824,316 RGD:2290271
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:2290271
G CBL Cbl proto-oncogene JBrowse link 11 119,206,339 119,308,149 RGD:2290271
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 35,871,491 35,880,360 RGD:2290271
G CD28 CD28 molecule JBrowse link 2 203,706,475 203,739,756 RGD:2290271
G CNTF ciliary neurotrophic factor JBrowse link 11 58,622,665 58,625,733 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 17 40,015,440 40,017,813 RGD:2290271
G DCN decorin JBrowse link 12 91,140,484 91,182,817 RGD:2290271
G EPO erythropoietin JBrowse link 7 100,720,468 100,723,700 RGD:2290271
G EPOR erythropoietin receptor JBrowse link 19 11,377,207 11,384,314 RGD:2290271
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 17 39,688,094 39,728,660 RGD:9068941
G ERBB3 erb-b2 receptor tyrosine kinase 3 JBrowse link 12 56,080,108 56,103,505 RGD:2290271
G ERBB4 erb-b2 receptor tyrosine kinase 4 JBrowse link 2 211,375,717 212,538,802 RGD:2290271
G F2 coagulation factor II, thrombin JBrowse link 11 46,719,213 46,739,506 RGD:2290271
G F2R coagulation factor II thrombin receptor JBrowse link 5 76,716,126 76,735,770 RGD:2290271
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 76,819,030 76,835,315 RGD:2290271
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 8 38,411,138 38,468,834 RGD:2290271
G FGR FGR proto-oncogene, Src family tyrosine kinase JBrowse link 1 27,612,064 27,635,561 RGD:2290271
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 13 28,300,346 28,495,128 RGD:2290271
G FLT3 fms related receptor tyrosine kinase 3 JBrowse link 13 28,003,274 28,100,587 RGD:2290271
G FPR2 formyl peptide receptor 2 JBrowse link 19 51,752,026 51,770,531 RGD:9068941
G FSHR follicle stimulating hormone receptor JBrowse link 2 48,953,161 49,154,527 RGD:2290271
G FYN FYN proto-oncogene, Src family tyrosine kinase JBrowse link 6 111,660,332 111,873,452 RGD:2290271
G GAB1 GRB2 associated binding protein 1 JBrowse link 4 143,336,876 143,474,565 RGD:2290271
G GH1 growth hormone 1 JBrowse link 17 63,917,203 63,918,839 RGD:2290271
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 7 1,086,807 1,093,815 RGD:2290271
G HAX1 HCLS1 associated protein X-1 JBrowse link 1 154,272,629 154,275,875 RGD:2290271
G HCLS1 hematopoietic cell-specific Lyn substrate 1 JBrowse link 3 121,631,399 121,660,903 RGD:2290271
G HCST hematopoietic cell signal transducer JBrowse link 19 35,902,365 35,904,377 RGD:2290271
G HGF hepatocyte growth factor JBrowse link 7 81,699,006 81,770,438 RGD:2290271
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:2290271
G IGF1R insulin like growth factor 1 receptor JBrowse link 15 98,648,539 98,964,530 RGD:2290271
G IL18 interleukin 18 JBrowse link 11 112,143,251 112,164,104 RGD:2290271
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:2290271
G INSR insulin receptor JBrowse link 19 7,112,257 7,294,414 RGD:2290271
G IRS2 insulin receptor substrate 2 JBrowse link 13 109,752,695 109,786,583 RGD:2290271
G JAK2 Janus kinase 2 JBrowse link 9 4,985,086 5,129,948 RGD:2290271
G KDR kinase insert domain receptor JBrowse link 4 55,078,481 55,125,595 RGD:2290271
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 54,657,928 54,740,715 RGD:2290271
G LEP leptin JBrowse link 7 128,241,201 128,257,629 RGD:2290271
G LYN LYN proto-oncogene, Src family tyrosine kinase JBrowse link 8 55,876,041 56,014,169 RGD:2290271
G MAZ MYC associated zinc finger protein JBrowse link 16 29,806,081 29,811,171 RGD:2290271
G MYDGF myeloid derived growth factor JBrowse link 19 4,657,545 4,670,391 RGD:2290271
G MYOC myocilin JBrowse link 1 171,635,417 171,652,688 RGD:2290271
G NCF1 neutrophil cytosolic factor 1 JBrowse link 7 74,773,962 74,789,376 RGD:2290271
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 15 55,826,917 55,993,612 RGD:2290271
G NKX3-1 NK3 homeobox 1 JBrowse link 8 23,678,693 23,682,938 RGD:2290271
G NRG1 neuregulin 1 JBrowse link 8 31,639,245 32,774,046 RGD:9068941
G NTF3 neurotrophin 3 JBrowse link 12 5,432,108 5,495,299 RGD:2290271
G NTRK1 neurotrophic receptor tyrosine kinase 1 JBrowse link 1 156,815,750 156,881,850 RGD:2290271
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,668,458 85,027,070 RGD:2290271
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 15 87,859,749 88,256,796 RGD:2290271
G OSM oncostatin M JBrowse link 22 30,262,829 30,266,851 RGD:2290271
G PDGFA platelet derived growth factor subunit A JBrowse link 7 497,245 520,668 RGD:2290271
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:2290271
G PDGFC platelet derived growth factor C JBrowse link 4 156,760,454 156,971,799 RGD:2290271
G PDGFD platelet derived growth factor D JBrowse link 11 103,907,189 104,164,147 RGD:2290271
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 4 54,229,127 54,298,247 RGD:2290271
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 150,113,839 150,155,845 RGD:2290271
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 10 96,593,312 96,720,514 RGD:2290271
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 179,148,114 179,240,093 RGD:2290271
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta JBrowse link 3 138,652,698 138,834,928 RGD:2290271
G PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta JBrowse link 1 9,629,889 9,729,114 RGD:2290271
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 7 106,865,282 106,908,980 RGD:2290271
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 5 68,215,737 68,301,821 RGD:2290271
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 17 8,878,916 8,965,712 RGD:2290271
G PLD2 phospholipase D2 JBrowse link 17 4,807,152 4,823,432 RGD:9068941
G PLXNB1 plexin B1 JBrowse link 3 48,403,854 48,430,324 RGD:2290271
G PPARD peroxisome proliferator activated receptor delta JBrowse link 6 35,342,558 35,428,191 RGD:2290271
G PRR5 proline rich 5 JBrowse link 22 44,668,547 44,737,681 RGD:2290271
G PRR5L proline rich 5 like JBrowse link 11 36,296,288 36,465,204 RGD:2290271
G PTK2 protein tyrosine kinase 2 JBrowse link 8 140,657,900 141,002,079 RGD:2290271
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 6,946,577 6,961,316 RGD:2290271
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,180 40,357,643 RGD:9068941
G RELN reelin JBrowse link 7 103,471,784 103,989,658 RGD:2290271
G RGL2 ral guanine nucleotide dissociation stimulator like 2 JBrowse link 6 33,291,654 33,299,388 RGD:2290271
G ROR1 receptor tyrosine kinase like orphan receptor 1 JBrowse link 1 63,774,017 64,181,498 RGD:2290271
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 9 91,722,598 91,950,228 RGD:2290271
G SELP selectin P JBrowse link 1 169,588,849 169,630,125 RGD:2290271
G SEMA4D semaphorin 4D JBrowse link 9 89,360,787 89,498,113 RGD:2290271
G SERPINA12 serpin family A member 12 JBrowse link 14 94,481,651 94,517,844 RGD:2290271
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:2290271
G SOX9 SRY-box transcription factor 9 JBrowse link 17 72,121,020 72,126,416 RGD:2290271
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,406,050 RGD:2290271
G TEK TEK receptor tyrosine kinase JBrowse link 9 27,109,141 27,230,178 RGD:2290271
G TGFB2 transforming growth factor beta 2 JBrowse link 1 218,345,284 218,444,619 RGD:2290271
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:2290271
G UBE3A ubiquitin protein ligase E3A JBrowse link 15 25,333,728 25,439,381 RGD:2290271
G UNC5B unc-5 netrin receptor B JBrowse link 10 71,212,535 71,302,879 RGD:2290271
G WNT16 Wnt family member 16 JBrowse link 7 121,325,367 121,341,104 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18539
    signaling 7162
      signal transduction 6517
        intracellular signal transduction 2956
          regulation of intracellular signal transduction 1962
            regulation of phosphatidylinositol 3-kinase signaling 135
              negative regulation of phosphatidylinositol 3-kinase signaling 17
              positive regulation of phosphatidylinositol 3-kinase signaling 94
Path 2
Term Annotations click to browse term
  biological_process 18539
    biological regulation 13174
      regulation of biological process 12530
        regulation of cellular process 11929
          signal transduction 6517
            intracellular signal transduction 2956
              inositol lipid-mediated signaling 204
                phosphatidylinositol-mediated signaling 201
                  phosphatidylinositol 3-kinase signaling 163
                    regulation of phosphatidylinositol 3-kinase signaling 135
                      negative regulation of phosphatidylinositol 3-kinase signaling 17
                      positive regulation of phosphatidylinositol 3-kinase signaling 94
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.