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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
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Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


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regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 JBrowse link 7 25,461,702 25,477,647 RGD:9068941
G Cep55 centrosomal protein 55 JBrowse link 19 38,054,970 38,074,425 RGD:2290270
G Crnn cornulin JBrowse link 3 93,144,789 93,149,818 RGD:2290270
G Dipk2a divergent protein kinase domain 2A JBrowse link 9 94,517,864 94,538,081 RGD:2290270
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:2290270
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 JBrowse link 12 84,373,875 84,409,029 RGD:2290270
G Fbxl2 F-box and leucine-rich repeat protein 2 JBrowse link 9 113,958,557 114,026,803 RGD:2290270
G Lime1 Lck interacting transmembrane adaptor 1 JBrowse link 2 181,381,235 181,383,628 RGD:2290270
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B JBrowse link 2 158,666,733 158,766,334 RGD:2290270
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 JBrowse link 5 103,425,192 103,598,361 RGD:2290270
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 2 117,279,983 117,342,877 RGD:2290270
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 13 23,477,049 23,488,858 RGD:2290270
G Cryba1 crystallin, beta A1 JBrowse link 11 77,718,614 77,725,293 RGD:2290270
G Dab2ip disabled 2 interacting protein JBrowse link 2 35,558,446 35,730,994 RGD:2290270
G Inpp5e inositol polyphosphate-5-phosphatase E JBrowse link 2 26,396,249 26,409,244 RGD:2290270
G Klf4 Kruppel-like factor 4 (gut) JBrowse link 4 55,527,137 55,532,475 RGD:2290270
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 11 62,315,663 62,457,414 RGD:2290270
G Nlrc3 NLR family, CARD domain containing 3 JBrowse link 16 3,943,807 3,979,017 RGD:2290270
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 7 15,937,835 15,946,108 RGD:2290270
G Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 11 58,994,256 59,136,375 RGD:2290270
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 11 3,319,241 3,342,971 RGD:2290270
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 JBrowse link 1 79,794,317 79,858,665 RGD:2290270
G Slc9a3r1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 JBrowse link 11 115,163,341 115,181,178 RGD:2290270
G Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 JBrowse link 17 24,639,281 24,650,305 RGD:2290270
G Stambp STAM binding protein JBrowse link 6 83,543,206 83,575,826 RGD:2290270
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:2290270
G Twist1 twist basic helix-loop-helix transcription factor 1 JBrowse link 12 33,957,671 33,959,831 RGD:2290270
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora3 adenosine A3 receptor JBrowse link 3 105,904,421 105,908,928 RGD:2290270
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 10 127,075,269 127,093,170 RGD:2290270
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:2290270
G Angpt1 angiopoietin 1 JBrowse link 15 42,424,667 42,676,977 RGD:2290270
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:2290270
G Cbl Casitas B-lineage lymphoma JBrowse link 9 44,142,976 44,234,259 RGD:2290270
G Ccl5 chemokine (C-C motif) ligand 5 JBrowse link 11 83,525,778 83,530,518 RGD:2290270
G Cd28 CD28 antigen JBrowse link 1 60,746,388 60,773,359 RGD:2290270
G Cntf ciliary neurotrophic factor JBrowse link 19 12,763,528 12,765,632 RGD:2290270
G Csf3 colony stimulating factor 3 (granulocyte) JBrowse link 11 98,700,183 98,703,631 RGD:2290270
G Dcn decorin JBrowse link 10 97,479,500 97,518,163 RGD:2290270
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 11 98,412,484 98,437,716 RGD:2290270
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 1 68,031,884 69,108,576 RGD:2290270
G F2 coagulation factor II JBrowse link 2 91,612,397 91,636,457 RGD:2290270
G F2r coagulation factor II (thrombin) receptor JBrowse link 13 95,601,780 95,618,466 RGD:2290270
G F2rl1 coagulation factor II (thrombin) receptor-like 1 JBrowse link 13 95,511,718 95,525,240 RGD:2290270
G Fgr FGR proto-oncogene, Src family tyrosine kinase JBrowse link 4 132,974,095 133,001,893 RGD:2290270
G Flt1 FMS-like tyrosine kinase 1 JBrowse link 5 147,561,604 147,726,438 RGD:2290270
G Fpr2 formyl peptide receptor 2 JBrowse link 17 17,887,824 17,893,952 RGD:2290270
G Fshr follicle stimulating hormone receptor JBrowse link 17 88,984,952 89,200,675 RGD:2290270
G Fyn Fyn proto-oncogene JBrowse link 10 39,369,743 39,565,381 RGD:2290270
G Gh growth hormone JBrowse link 11 106,300,261 106,303,703 RGD:9068941
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 5 139,423,150 139,427,800 RGD:2290270
G Hax1 HCLS1 associated X-1 JBrowse link 3 89,995,446 89,998,716 RGD:2290270
G Hcls1 hematopoietic cell specific Lyn substrate 1 JBrowse link 16 36,934,983 36,963,214 RGD:2290270
G Hcst hematopoietic cell signal transducer JBrowse link 7 30,417,712 30,419,854 RGD:2290270
G Hgf hepatocyte growth factor JBrowse link 5 16,553,495 16,619,439 RGD:2290270
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:2290270
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:2290270
G Il18 interleukin 18 JBrowse link 9 50,554,700 50,581,841 RGD:2290270
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:2290270
G Insr insulin receptor JBrowse link 8 3,150,922 3,279,649 RGD:2290270
G Jak2 Janus kinase 2 JBrowse link 19 29,251,803 29,313,095 RGD:2290270
G Kdr kinase insert domain protein receptor JBrowse link 5 75,932,827 75,979,072 RGD:2290270
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:2290270
G Maz MYC-associated zinc finger protein (purine-binding transcription factor) JBrowse link 7 127,021,450 127,027,188 RGD:2290270
G Mydgf myeloid derived growth factor JBrowse link 17 56,176,541 56,183,920 RGD:2290270
G Myoc myocilin JBrowse link 1 162,639,150 162,649,694 RGD:2290270
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 5 134,220,053 134,229,628 RGD:2290270
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 JBrowse link 9 72,662,331 72,749,851 RGD:9068941
G Nkx3-1 NK3 homeobox 1 JBrowse link 14 69,190,692 69,194,658 RGD:2290270
G Nrg1 neuregulin 1 JBrowse link 8 31,807,452 32,891,609 RGD:2290270
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 JBrowse link 3 87,778,244 87,795,242 RGD:2290270
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 JBrowse link 13 58,806,472 59,133,970 RGD:2290270
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 JBrowse link 7 78,179,986 78,581,034 RGD:2290270
G Osm oncostatin M JBrowse link 11 4,236,785 4,241,026 RGD:2290270
G Pdgfa platelet derived growth factor, alpha JBrowse link 5 138,976,014 139,000,792 RGD:2290270
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:2290270
G Pdgfc platelet-derived growth factor, C polypeptide JBrowse link 3 81,036,416 81,214,040 RGD:2290270
G Pdgfd platelet-derived growth factor, D polypeptide JBrowse link 9 6,168,363 6,534,284 RGD:2290270
G Pdgfrb platelet derived growth factor receptor, beta polypeptide JBrowse link 18 61,045,127 61,085,067 RGD:2290270
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 19 41,272,541 41,385,102 RGD:2290270
G Pld2 phospholipase D2 JBrowse link 11 70,539,492 70,558,110 RGD:2290270
G Plxnb1 plexin B1 JBrowse link 9 109,093,849 109,119,915 RGD:2290270
G Ppard peroxisome proliferator activator receptor delta JBrowse link 17 28,232,754 28,301,469 RGD:2290270
G Prr5 proline rich 5 (renal) JBrowse link 15 84,663,206 84,706,409 RGD:2290270
G Prr5l proline rich 5 like JBrowse link 2 101,713,110 101,883,052 RGD:2290270
G Ptk2 PTK2 protein tyrosine kinase 2 JBrowse link 15 73,205,102 73,423,820 RGD:2290270
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 6 124,720,707 124,738,709 RGD:2290270
G Rara retinoic acid receptor, alpha JBrowse link 11 98,927,800 98,974,942 RGD:2290270
G Reln reelin JBrowse link 5 21,884,454 22,344,705 RGD:2290270
G Rgl2 ral guanine nucleotide dissociation stimulator-like 2 JBrowse link 17 33,929,514 33,937,687 RGD:2290270
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 4 100,095,791 100,444,806 RGD:2290270
G Ror2 receptor tyrosine kinase-like orphan receptor 2 JBrowse link 13 53,109,317 53,286,124 RGD:2290270
G Selp selectin, platelet JBrowse link 1 164,115,264 164,150,026 RGD:2290270
G Sema4d sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D JBrowse link 13 51,685,529 51,793,678 RGD:2290270
G Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 JBrowse link 12 104,028,769 104,044,443 RGD:2290270
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:2290270
G Sox9 SRY (sex determining region Y)-box 9 JBrowse link 11 112,782,210 112,787,757 RGD:2290270
G Tek TEK receptor tyrosine kinase JBrowse link 4 94,739,086 94,874,976 RGD:2290270
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:2290270
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:2290270
G Ube3a ubiquitin protein ligase E3A JBrowse link 7 59,228,750 59,310,837 RGD:2290270
G Unc5b unc-5 netrin receptor B JBrowse link 10 60,762,594 60,831,581 RGD:2290270
G Wnt16 wingless-type MMTV integration site family, member 16 JBrowse link 6 22,288,178 22,298,522 RGD:2290270

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23311
    signaling 6907
      signal transduction 6287
        intracellular signal transduction 2546
          regulation of intracellular signal transduction 1704
            regulation of phosphatidylinositol 3-kinase signaling 102
              negative regulation of phosphatidylinositol 3-kinase signaling 16
              positive regulation of phosphatidylinositol 3-kinase signaling 75
Path 2
Term Annotations click to browse term
  biological_process 23311
    biological regulation 13016
      regulation of biological process 12408
        regulation of cellular process 11859
          signal transduction 6287
            intracellular signal transduction 2546
              inositol lipid-mediated signaling 172
                phosphatidylinositol-mediated signaling 169
                  phosphatidylinositol 3-kinase signaling 134
                    regulation of phosphatidylinositol 3-kinase signaling 102
                      negative regulation of phosphatidylinositol 3-kinase signaling 16
                      positive regulation of phosphatidylinositol 3-kinase signaling 75
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.