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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of phosphatidylinositol 3-kinase signaling
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Accession:GO:0014066 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms:exact_synonym: regulation of PI3K cascade;   regulation of phosphoinositide 3-kinase cascade
 related_synonym: regulation of PI 3-kinase cascade;   regulation of phosphatidylinositol 3-kinase cascade


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regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 6 49,437,308 49,460,614 RGD:9068941
G CEP55 centrosomal protein 55 JBrowse link 14 104,957,256 104,980,690 RGD:14298760
G CRNN cornulin JBrowse link 4 96,933,221 96,938,980 RGD:14298760
G DIPK2A divergent protein kinase domain 2A JBrowse link 13 84,634,716 84,656,112 RGD:14298760
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:14298760
G ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 (inactive) JBrowse link 7 97,270,698 97,316,578 RGD:9068941
G FBXL2 F-box and leucine rich repeat protein 2 JBrowse link 13 19,128,145 19,206,458 RGD:14298760
G LIME1 Lck interacting transmembrane adaptor 1 JBrowse link 17 62,652,618 62,655,342 RGD:9068941
G PPP1R16B protein phosphatase 1 regulatory subunit 16B JBrowse link 17 41,753,697 41,866,671 RGD:14298760
G PTPN13 protein tyrosine phosphatase non-receptor type 13 JBrowse link 8 132,035,170 132,200,425 RGD:14298760
G RASGRP1 RAS guanyl releasing protein 1 JBrowse link 1 132,702,495 132,786,536 RGD:14298760
negative regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTN2A2 butyrophilin subfamily 2 member A2 JBrowse link 7 20,954,229 20,968,390 RGD:14298760
G CRYBA1 crystallin beta A1 JBrowse link 12 45,466,051 45,473,110 RGD:9068941
G DAB2IP DAB2 interacting protein JBrowse link 1 261,732,280 261,859,833 RGD:14298760
G INPP5E inositol polyphosphate-5-phosphatase E RGD:9068941
G KLF4 Kruppel like factor 4 JBrowse link 1 248,604,817 248,609,574 RGD:9068941
G NCOR1 nuclear receptor corepressor 1 JBrowse link 12 59,256,868 59,392,564 RGD:9068941
G NLRC3 NLR family CARD domain containing 3 JBrowse link 3 38,673,590 38,719,188 RGD:9068941
G NOP53 NOP53 ribosome biogenesis factor JBrowse link 6 53,443,453 53,451,707 RGD:14298760
G OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF JBrowse link 2 51,317,538 51,534,246 RGD:9068941
G PIK3IP1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 14 48,040,848 48,051,660 RGD:14298760
G SERPINE2 serpin family E member 2 JBrowse link 15 125,748,383 125,777,788 RGD:14298760
G SLC9A3R1 SLC9A3 regulator 1 JBrowse link 12 6,466,138 6,483,539 RGD:14298760
G SLC9A3R2 SLC9A3 regulator 2 JBrowse link 3 39,942,366 39,952,824 RGD:9068941
G STAMBP STAM binding protein JBrowse link 3 69,156,012 69,188,256 RGD:14298760
G TSC2 TSC complex subunit 2 JBrowse link 3 39,898,924 39,935,579 RGD:9068941
G TWIST1 twist family bHLH transcription factor 1 JBrowse link 9 88,286,911 88,290,131 RGD:9068941
positive regulation of phosphatidylinositol 3-kinase signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 JBrowse link 5 23,015,777 23,035,943 RGD:9068941
G AGT angiotensinogen JBrowse link 14 59,643,030 59,656,835 RGD:14298760
G ANGPT1 angiopoietin 1 JBrowse link 4 29,925,203 30,233,434 RGD:14298760
G CAT catalase JBrowse link 2 26,493,664 26,533,881 RGD:14298760
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:14298760
G CCL5 C-C motif chemokine ligand 5 JBrowse link 12 39,652,731 39,659,121 RGD:14298760
G CD28 CD28 molecule JBrowse link 15 107,128,103 107,155,431 RGD:14298760
G CNTF ciliary neurotrophic factor JBrowse link 2 12,492,777 12,495,401 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 12 22,333,445 22,335,949 RGD:9068941
G DCN decorin JBrowse link 5 91,678,601 91,713,925 RGD:14298760
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 12 22,591,621 22,621,384 RGD:9068941
G ERBB4 erb-b2 receptor tyrosine kinase 4 JBrowse link 15 113,966,573 115,096,984 RGD:14298760
G F2 coagulation factor II, thrombin JBrowse link 2 15,793,257 15,819,151 RGD:14298760
G F2R coagulation factor II thrombin receptor JBrowse link 2 85,642,794 85,659,133 RGD:14298760
G F2RL1 F2R like trypsin receptor 1 JBrowse link 2 85,732,082 85,747,552 RGD:14298760
G FGR FGR proto-oncogene, Src family tyrosine kinase JBrowse link 6 84,809,534 84,830,401 RGD:14298760
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 11 5,620,698 5,797,095 RGD:9068941
G FSHR follicle stimulating hormone receptor JBrowse link 3 91,607,236 91,775,255 RGD:14298760
G FYN FYN proto-oncogene, Src family tyrosine kinase JBrowse link 1 77,584,675 77,810,605 RGD:9068941
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 3 711,427 715,982 RGD:14298760
G HAX1 HCLS1 associated protein X-1 JBrowse link 4 95,467,629 95,470,972 RGD:9068941
G HCLS1 hematopoietic cell-specific Lyn substrate 1 JBrowse link 13 138,852,387 138,883,088 RGD:9068941
G HCST hematopoietic cell signal transducer JBrowse link 6 45,304,744 45,309,048 RGD:14298760
G HGF hepatocyte growth factor JBrowse link 9 98,437,771 98,513,573 RGD:14298760
G IGF1 insulin like growth factor 1 JBrowse link 5 81,762,027 81,909,253 RGD:14298760
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G IL18 interleukin 18 JBrowse link 9 39,839,959 39,861,258 RGD:14298760
G INS insulin JBrowse link 2 1,496,842 1,498,052 RGD:14298760
G INSR insulin receptor JBrowse link 2 71,797,209 71,939,923 RGD:14298760
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 8 41,809,116 41,856,379 RGD:14298760
G LEP leptin JBrowse link 18 20,106,867 20,124,071 RGD:14298760
G LOC106504546 serpin A12 JBrowse link 7 115,720,892 115,734,810 RGD:14298760
G MAZ MYC associated zinc finger protein JBrowse link 3 18,043,032 18,047,531 RGD:14298760
G MYDGF myeloid derived growth factor JBrowse link 2 74,185,042 74,202,306 RGD:14298760
G MYOC myocilin JBrowse link 9 114,087,370 114,098,765 RGD:14298760
G NCF1 neutrophil cytosolic factor 1 JBrowse link 3 11,820,367 11,834,394 RGD:14298760
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 1 115,941,945 116,069,884 RGD:14298760
G NKX3-1 NK3 homeobox 1 JBrowse link 14 7,783,296 7,787,036 RGD:14298760
G NRG1 neuregulin 1 JBrowse link 15 52,625,550 53,688,003 RGD:9068941
G NTRK1 neurotrophic receptor tyrosine kinase 1 JBrowse link 4 93,219,509 93,237,944 RGD:14298760
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 10 30,030,050 30,429,938 RGD:14298760
G NTRK3 neurotrophic receptor tyrosine kinase 3 JBrowse link 1 191,535,262 191,941,675 RGD:14298760
G OSM oncostatin M JBrowse link 14 47,242,767 47,246,836 RGD:14298760
G PDGFA platelet derived growth factor subunit A JBrowse link 3 296,399 322,967 RGD:14298760
G PDGFB platelet derived growth factor subunit B RGD:14298760
G PDGFC platelet derived growth factor C JBrowse link 8 45,579,065 45,808,789 RGD:14298760
G PDGFD platelet derived growth factor D JBrowse link 9 34,388,636 34,621,227 RGD:14298760
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:14298760
G PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 JBrowse link 14 108,038,396 108,303,942 RGD:14298760
G PLD2 phospholipase D2 JBrowse link 12 52,073,913 52,087,804 RGD:9068941
G PLXNB1 plexin B1 JBrowse link 13 31,113,910 31,140,133 RGD:14298760
G PPARD peroxisome proliferator activated receptor delta JBrowse link 7 31,222,533 31,295,221 RGD:14298760
G PRR5 proline rich 5 JBrowse link 5 4,467,231 4,525,610 RGD:14298760
G PRR5L proline rich 5 like JBrowse link 2 24,646,865 24,812,642 RGD:14298760
G PTK2 protein tyrosine kinase 2 JBrowse link 4 2,656,606 2,896,060 RGD:14298760
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 5 63,762,109 63,779,086 RGD:14298760
G RARA retinoic acid receptor alpha JBrowse link 12 22,047,449 22,085,759 RGD:9068941
G RELN reelin JBrowse link 9 103,460,855 103,963,728 RGD:14298760
G RGL2 ral guanine nucleotide dissociation stimulator like 2 JBrowse link 7 29,655,530 29,662,375 RGD:14298760
G ROR1 receptor tyrosine kinase like orphan receptor 1 JBrowse link 6 148,314,575 148,834,659 RGD:14298760
G ROR2 receptor tyrosine kinase like orphan receptor 2 JBrowse link 14 2,803,840 3,035,384 RGD:14298760
G SELP selectin P JBrowse link 4 81,376,804 81,401,240 RGD:9068941
G SEMA4D semaphorin 4D JBrowse link 14 957,074 1,078,522 RGD:14298760
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:14298760
G SOX9 SRY-box transcription factor 9 JBrowse link 12 8,642,154 8,647,315 RGD:14298760
G TEK TEK receptor tyrosine kinase JBrowse link 1 195,938,177 196,052,294 RGD:14298760
G TGFB2 transforming growth factor beta 2 JBrowse link 10 8,306,136 8,435,307 RGD:14298760
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
G UBE3A ubiquitin protein ligase E3A JBrowse link 1 141,887,179 142,001,595 RGD:14298760
G UNC5B unc-5 netrin receptor B JBrowse link 14 74,120,055 74,208,055 RGD:14298760
G WNT16 Wnt family member 16 JBrowse link 18 25,621,802 25,633,730 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16412
    signaling 6413
      signal transduction 5870
        intracellular signal transduction 2465
          regulation of intracellular signal transduction 1620
            regulation of phosphatidylinositol 3-kinase signaling 99
              negative regulation of phosphatidylinositol 3-kinase signaling 16
              positive regulation of phosphatidylinositol 3-kinase signaling 72
Path 2
Term Annotations click to browse term
  biological_process 16412
    biological regulation 11883
      regulation of biological process 11314
        regulation of cellular process 10867
          signal transduction 5870
            intracellular signal transduction 2465
              inositol lipid-mediated signaling 170
                phosphatidylinositol-mediated signaling 167
                  phosphatidylinositol 3-kinase signaling 133
                    regulation of phosphatidylinositol 3-kinase signaling 99
                      negative regulation of phosphatidylinositol 3-kinase signaling 16
                      positive regulation of phosphatidylinositol 3-kinase signaling 72
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.