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ONTOLOGY REPORT - ANNOTATIONS


Term:response to isoquinoline alkaloid
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Accession:GO:0014072 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


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response to isoquinoline alkaloid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11041186
cellular response to isoquinoline alkaloid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:5131909
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:12790719
cellular response to morphine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:1600115
RGD:13825193
RGD:1624291
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:2313012
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:11557986
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:4889899
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6483056
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1600115
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 10 82,800,704 82,816,735 RGD:1624291
RGD:1600115
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7488923
response to codeine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11041146
response to morphine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11041102
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:11099987
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:5128863
G Adcy5 adenylate cyclase 5 JBrowse link 11 68,695,839 68,842,452 RGD:13464135
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:1624291
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2314642
RGD:2314667
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:10059657
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:13463594
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:4890043
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:7248563
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1624291
RGD:1600115
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:1624291
RGD:1600115
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:1581828
RGD:4892606
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 JBrowse link 1 259,692,020 259,818,922 RGD:9685461
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:11341805
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:9685019
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 80,214,691 80,221,417 RGD:2293776
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:2307381
G Gnao1 G protein subunit alpha o1 JBrowse link 19 11,513,201 11,669,578 RGD:2302014
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:13506244
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:11051960
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13506833
G Grk3 G protein-coupled receptor kinase 3 JBrowse link 12 49,626,871 49,750,389 RGD:13506833
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:727454
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1626676
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 3 150,801,289 150,802,935 RGD:11560529
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317407
G Mir338 microRNA 338 JBrowse link 10 109,195,251 109,195,316 RGD:13463594
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:10040983
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:2316569
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:9831397
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:2316627
RGD:9831397
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:2308891
G Pea15 proliferation and apoptosis adaptor protein 15 JBrowse link 13 90,579,844 90,589,466 RGD:2326031
G Penk proenkephalin JBrowse link 5 17,056,412 17,061,762 RGD:10003095
G Pitx3 paired-like homeodomain 3 JBrowse link 1 265,886,766 265,899,947 RGD:11535121
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:2299883
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:1624291
RGD:1600115
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha JBrowse link 15 43,673,958 43,733,182 RGD:1624291
RGD:1600115
G Ppp5c protein phosphatase 5, catalytic subunit JBrowse link 1 78,944,054 78,968,361 RGD:1624291
RGD:1600115
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:1624291
RGD:1600115
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298784
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:13524518
RGD:13524581
G Srr serine racemase JBrowse link 10 61,756,138 61,772,327 RGD:2302212
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:2304334
G Tac3 tachykinin precursor 3 JBrowse link 7 71,023,976 71,030,582 RGD:2305965
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:2304334
G Tacr3 tachykinin receptor 3 JBrowse link 2 240,021,152 240,118,971 RGD:2305965
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7777128

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    response to stimulus 9928
      response to chemical 6195
        response to organic substance 3747
          response to organic cyclic compound 1449
            response to isoquinoline alkaloid 60
              cellular response to isoquinoline alkaloid + 10
              response to codeine + 1
              response to dextromethorphan + 0
              response to morphine + 58
Path 2
Term Annotations click to browse term
  biological_process 18166
    response to stimulus 9928
      response to chemical 6195
        response to organic substance 3747
          response to organonitrogen compound 1420
            response to alkaloid 183
              response to isoquinoline alkaloid 60
                cellular response to isoquinoline alkaloid + 10
                response to codeine + 1
                response to dextromethorphan + 0
                response to morphine + 58
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.