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ONTOLOGY REPORT - ANNOTATIONS


Term:response to amine
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Accession:GO:0014075 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
Synonyms:exact_synonym: response to amine stimulus


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response to amine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 IEP dimethylnitrosamine RGD PMID:17383642 RGD:10449031 NCBI chr 3:5,519,921...5,558,390
Ensembl chr 3:5,519,990...5,558,166
JBrowse link
G Adipor2 adiponectin receptor 2 IEP dietary cysteamine RGD PMID:17696487 RGD:21079417 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Arg1 arginase 1 IEP spermine RGD PMID:16459053 RGD:4143195 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 IEP spermine RGD PMID:16168957 RGD:4110830 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Asl argininosuccinate lyase IEP spermine RGD PMID:16168957 RGD:4110830 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Ass1 argininosuccinate synthase 1 IEP spermine RGD PMID:16168957 RGD:4110830 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP RGD PMID:2864015 RGD:2303531 NCBI chr 6:26,657,507...26,680,459
Ensembl chr 6:26,657,780...26,680,284
JBrowse link
G Cdk1 cyclin-dependent kinase 1 IEP dimethylnitrosamine RGD PMID:16155410 RGD:2316487 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 IEP RGD PMID:2864015 RGD:2303531 NCBI chr 9:74,113,437...74,236,274
Ensembl chr 9:74,124,016...74,236,274
JBrowse link
G Ctsb cathepsin B IEP polyamine depletion RGD PMID:17371271 RGD:2315519 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 IEP ketamine RGD PMID:19918184 RGD:2325941 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP ketamine RGD PMID:19918184 RGD:2325941 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP ketamine RGD PMID:19918184 RGD:2325941 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Hnmt histamine N-methyltransferase IEP RGD PMID:3952132 RGD:2316841 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Itga2 integrin subunit alpha 2 IEP polyamines RGD PMID:9252524 RGD:2307415 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IEP aminophosphonovaleric acid RGD PMID:18775767 RGD:9685735 NCBI chr 1:102,414,352...102,456,718
Ensembl chr 1:102,414,625...102,456,411
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IEP aminophosphonovaleric acid RGD PMID:18775767 RGD:9685735 NCBI chr 7:54,978,453...55,159,362
Ensembl chr 7:54,980,120...55,159,351
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEP Diethylnitrosamine RGD PMID:18081878 RGD:2304231 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 IEP 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine RGD PMID:19639176 RGD:5132866 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IDA Thioacetamide RGD PMID:29444417 RGD:25823192 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pdxk pyridoxal kinase IEP RGD PMID:17115225 RGD:2303034 NCBI chr20:10,930,651...10,952,194
Ensembl chr20:10,930,518...10,952,391
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B IEP N-nitrosomorpholine RGD PMID:14587038 RGD:2291845 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G Sphk1 sphingosine kinase 1 IEP sphingosine 1-phosphate RGD PMID:17164439 RGD:2311368 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Urod uroporphyrinogen decarboxylase IEP thioctamide (thioacetamide) RGD PMID:10365252 RGD:4145076 NCBI chr 5:135,855,429...135,859,515
Ensembl chr 5:135,855,433...135,859,643
JBrowse link
cellular response to amine stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ass1 argininosuccinate synthase 1 IEP polyaspartoyl L-arginine (PDR) RGD PMID:18457831 RGD:4140461 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP dopamine RGD PMID:19674091 RGD:4107725 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Hmbs hydroxymethylbilane synthase IEP 5-aminolevulinic acid RGD PMID:10416273 RGD:2303399 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IDA serotonin RGD PMID:1505525 RGD:61633 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Uros uroporphyrinogen III synthase IEP 5-aminolevulinic acid RGD PMID:10416273 RGD:2303399 NCBI chr 1:205,755,766...205,778,170
Ensembl chr 1:205,756,640...205,777,167
JBrowse link
response to amphetamine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO MGI:2155985 (MGI:1930839|PMID:11172060) RGD PMID:11172060 MGI:1930839 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra1b adrenoceptor alpha 1B ISO MGI:2148638 (MGI:2178201|PMID:11923452), (MGI:2667580|PMID:12871582) RGD PMID:11923452, PMID:12871582 MGI:2178201, MGI:2667580 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Asic1 acid sensing ion channel subunit 1 ISO (MGI:6108223|PMID:25828470) RGD PMID:25828470 MGI:6108223 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Calm1 calmodulin 1 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calm3 calmodulin 3 IEP RGD PMID:10854758 RGD:6892957 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Cnr2 cannabinoid receptor 2 IEP RGD PMID:20067581 RGD:2316187 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP RGD PMID:19582783 RGD:2314489 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP RGD PMID:19582783 RGD:2314489 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Dbh dopamine beta-hydroxylase IEA
ISO
GO_REF:0000107
MGI:1857556 (MGI:3574756|PMID:12370425)
Ensembl
RGD
PMID:12370425 GO_REF:0000107, MGI:3574756 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dcc DCC netrin 1 receptor IEP RGD PMID:17996376 RGD:2314370 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP RGD PMID:17105900 RGD:1599727 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP RGD PMID:20058175 RGD:2316239 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Drd1 dopamine receptor D1 IEP
ISO
IEA
MGI:1857158|MGI:2159306|MGI:3527157|MGI:94924|MGI:94925|MGI:94927|MGI:95819 (MGI:1195902|PMID:9261820), (MGI:1351083|PMID:10661513), (MGI:2137377|PMID:10222120), (MGI:3610905|PMID:11823893), (MGI:3626135|PMID:12097513), (MGI:3711455|PMID:16014726), (MGI:3797707|PMID:18486343), (MGI:4947459|PMID:21368124)
GO_REF:0000107
RGD
Ensembl
PMID:9261820, PMID:10222120, PMID:10661513, PMID:11823893, PMID:12097513, PMID:16014726, PMID:18486343, PMID:21368124, PMID:19145071 GO_REF:0000107, MGI:1195902, MGI:1351083, MGI:2137377, MGI:3610905, MGI:3626135, MGI:3711455, MGI:3797707, MGI:4947459, RGD:2311558 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 IEP
ISO
MGI:1857875|MGI:2656648|MGI:94925|MGI:99578 (MGI:3611062|PMID:12476322), (MGI:3626135|PMID:12097513), (MGI:3797707|PMID:18486343) RGD PMID:12097513, PMID:12476322, PMID:18486343, PMID:19145071 MGI:3611062, MGI:3626135, MGI:3797707, RGD:2311558 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 ISO MGI:94924|MGI:99578 (MGI:3626135|PMID:12097513) RGD PMID:12097513 MGI:3626135 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 IEA
ISO
GO_REF:0000107
MGI:2178631 (MGI:1097029|PMID:9323127)
Ensembl
RGD
PMID:9323127 GO_REF:0000107, MGI:1097029 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Drd5 dopamine receptor D5 IEA
ISO
GO_REF:0000107
MGI:99578 (MGI:3610905|PMID:11823893)
Ensembl
RGD
PMID:11823893 GO_REF:0000107, MGI:3610905 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Egr1 early growth response 1 IEP methamphetamine RGD PMID:21229349 RGD:5131852 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Gnal G protein subunit alpha L ISO MGI:2151207 (MGI:3719553|PMID:11404425) RGD PMID:11404425 MGI:3719553 NCBI chr18:62,805,406...62,946,133
Ensembl chr18:62,805,410...62,944,630
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 IEA
ISO
GO_REF:0000107
MGI:1928280|MGI:99578 (MGI:3629445|PMID:16638606), (MGI:3784348|PMID:15467708), (MGI:4947459|PMID:21368124)
Ensembl
RGD
PMID:15467708, PMID:16638606, PMID:21368124 GO_REF:0000107, MGI:3629445, MGI:3784348, MGI:4947459 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEA
ISO
GO_REF:0000107
MGI:1928285 (MGI:3656418|PMID:15731593)
Ensembl
RGD
PMID:15731593 GO_REF:0000107, MGI:3656418 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP RGD PMID:20422365 RGD:4107018 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Hdac1 histone deacetylase 1 IMP RGD PMID:18632938 RGD:9586741 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 IEP RGD PMID:22470541 RGD:9590269 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac6 histone deacetylase 6 IEP RGD PMID:25452209 RGD:9681719 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hdac9 histone deacetylase 9 IEP RGD PMID:25452209 RGD:9681719 NCBI chr 6:53,487,367...54,358,694
Ensembl chr 6:53,488,883...54,059,119
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO MGI:1857299 (MGI:50371|PMID:1777100), (MGI:65928|PMID:1432691) RGD PMID:1432691, PMID:1777100 MGI:50371, MGI:65928 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:21093552 RGD:4889145 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IEA
ISO
GO_REF:0000107
MGI:2429971 (MGI:3529728|PMID:12385813)
Ensembl
RGD
PMID:12385813 GO_REF:0000107, MGI:3529728 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nts neurotensin IEP RGD PMID:9786410 RGD:9698453 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IEP RGD PMID:17383105 RGD:2304140 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:17383105 RGD:2304140 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G Pde1b phosphodiesterase 1B ISO MGI:2676625|MGI:3604470|MGI:94860 (MGI:3761427|PMID:17010100), (MGI:3769297|PMID:17559891) RGD PMID:17010100, PMID:17559891 MGI:3761427, MGI:3769297 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B ISO MGI:97523 (MGI:3761427|PMID:17010100) RGD PMID:17010100 MGI:3761427 NCBI chr10:86,303,727...86,312,770
Ensembl chr10:86,303,727...86,312,762
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IEP RGD PMID:19932152 RGD:9999394 NCBI chr10:82,800,704...82,816,735
Ensembl chr10:82,800,704...82,816,731
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEP reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEP reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEP RGD PMID:23711322 RGD:9835030 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Ranbp2 RAN binding protein 2 IEP methamphetamine RGD PMID:23711322 RGD:9835030 NCBI chr20:28,027,054...28,076,664
NCBI chr20:28,365,538...28,375,676
Ensembl chr20:28,027,054...28,076,664
Ensembl chr20:28,027,054...28,076,664
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 IEP RGD PMID:19686726 RGD:10003122 NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
JBrowse link
G Rgs10 regulator of G-protein signaling 10 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 1:199,782,076...199,823,440
Ensembl chr 1:199,782,078...199,823,386
JBrowse link
G Rgs17 regulator of G-protein signaling 17 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 1:42,491,566...42,587,735
Ensembl chr 1:42,492,761...42,587,721
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs20 regulator of G-protein signaling 20 IEP RGD PMID:26321241 RGD:13524514 NCBI chr 5:14,367,498...14,494,048
Ensembl chr 5:14,415,606...14,494,756
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rgs7 regulator of G-protein signaling 7 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:93,095,659...93,534,452
Ensembl chr13:93,095,200...93,307,199
JBrowse link
G Rgs8 regulator of G-protein signaling 8 IEP RGD PMID:26321241 RGD:13524514 NCBI chr13:71,086,654...71,141,820
Ensembl chr13:71,086,745...71,141,075
JBrowse link
G Rgs9 regulator of G-protein signaling 9 IEP RGD PMID:26321241 RGD:13524514 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IEP
ISO
IEA
methamphetamine
MGI:3620458 (MGI:1096299|PMID:9275230)
GO_REF:0000107
RGD
Ensembl
PMID:9275230, PMID:21159748 GO_REF:0000107, MGI:1096299, RGD:5130776 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Sod1 superoxide dismutase 1 IEP RGD PMID:18452277 RGD:2302826 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 IEP RGD PMID:18632938 RGD:9586741 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Th tyrosine hydroxylase IEP RGD PMID:21078367 RGD:5128808 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 IEP RGD PMID:15542706 RGD:2303196 NCBI chr17:80,824,652...80,859,585
Ensembl chr17:80,826,846...80,860,195
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    response to stimulus 10580
      response to chemical 6337
        response to nitrogen compound 1552
          response to organonitrogen compound 1456
            response to amine 79
              cellular response to amine stimulus + 5
              response to amphetamine + 54
              response to hesperadin + 0
              response to methylamine + 0
              response to tamsulosin 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.