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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
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Accession:GO:0014809 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.


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regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casq1 calsequestrin 1 JBrowse link 13 90,592,676 90,602,365 RGD:1600115
RGD:1624291
RGD:13792537
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    cellular process 16139
      regulation of cellular process 11369
        regulation of calcium ion transport into cytosol 114
          regulation of release of sequestered calcium ion into cytosol 87
            regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 26
              regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
Path 2
Term Annotations click to browse term
  biological_process 18008
    biological regulation 12699
      regulation of biological quality 4158
        homeostatic process 1988
          chemical homeostasis 1281
            ion homeostasis 858
              cellular ion homeostasis 706
                cellular cation homeostasis 693
                  cellular metal ion homeostasis 633
                    cellular calcium ion homeostasis 521
                      regulation of cytosolic calcium ion concentration 424
                        positive regulation of cytosolic calcium ion concentration 368
                          calcium ion transport into cytosol 184
                            calcium ion transmembrane import into cytosol 160
                              release of sequestered calcium ion into cytosol 140
                                release of sequestered calcium ion into cytosol by endoplasmic reticulum 30
                                  release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 29
                                    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 26
                                      regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2
                                        negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
                                        positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.