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ONTOLOGY REPORT - ANNOTATIONS


Term:myotube differentiation involved in skeletal muscle regeneration
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Accession:GO:0014908 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.


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myotube differentiation involved in skeletal muscle regeneration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl9 BCL9, transcription coactivator ISO MGI:1933114 (MGI:4368064|PMID:19699733) RGD PMID:19699733 MGI:4368064 NCBI chr 2:199,334,644...199,420,083
Ensembl chr 2:199,334,664...199,354,793
JBrowse link
G Klf5 Kruppel-like factor 5 ISO MGI:4353154|MGI:4421792 (MGI:5823533|PMID:27743478) RGD PMID:27743478 MGI:5823533 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Myod1 myogenic differentiation 1 IEA
ISO
GO_REF:0000107
(MGI:48687|PMID:1348494)
Ensembl
RGD
PMID:1348494 GO_REF:0000107 MGI:48687 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
myoblast fusion involved in skeletal muscle regeneration term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(MGI:6282938|PMID:23575678)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23575678 GO_REF:0000024 GO_REF:0000107 MGI:6282938 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cd9 CD9 molecule ISS
ISO
GO_REF:0000024
(MGI:6282938|PMID:23575678)
UniProt
RGD
PMID:23575678 GO_REF:0000024 MGI:6282938 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Mymk myomaker, myoblast fusion factor ISO MGI:4841439 (MGI:5608518|PMID:25085416) RGD PMID:25085416 MGI:5608518 NCBI chr 3:5,608,243...5,617,689
Ensembl chr 3:5,608,243...5,617,225
JBrowse link
G Mymx myomixer, myoblast fusion factor ISO (MGI:6153677|PMID:29581287) RGD PMID:29581287 MGI:6153677 NCBI chr 9:17,781,397...17,783,074
Ensembl chr 9:17,782,395...17,782,664
JBrowse link
G Ptgfrn prostaglandin F2 receptor inhibitor ISS
ISO
IEA
GO_REF:0000024
(MGI:6282938|PMID:23575678)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:23575678 GO_REF:0000024 GO_REF:0000107 MGI:6282938 NCBI chr 2:203,423,143...203,494,391
Ensembl chr 2:203,423,143...203,494,391
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20030
    developmental process 6828
      developmental growth 819
        tissue regeneration 96
          skeletal muscle tissue regeneration 51
            myotube differentiation involved in skeletal muscle regeneration 8
              myoblast fusion involved in skeletal muscle regeneration 5
              myotube cell development involved in skeletal muscle regeneration 0
Path 2
Term Annotations click to browse term
  biological_process 20030
    cellular process 18802
      cellular developmental process 4458
        cell differentiation 4363
          muscle cell differentiation 419
            striated muscle cell differentiation 333
              myotube differentiation 129
                myotube differentiation involved in skeletal muscle regeneration 8
                  myoblast fusion involved in skeletal muscle regeneration 5
                  myotube cell development involved in skeletal muscle regeneration 0
paths to the root