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ONTOLOGY REPORT - ANNOTATIONS


Term:dystroglycan complex
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Accession:GO:0016011 term browser browse the term
Definition:A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.


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dystroglycan complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dag1 dystroglycan 1 JBrowse link 8 116,980,501 116,993,182 RGD:1624291
G Sgca sarcoglycan, alpha JBrowse link 10 82,770,905 82,785,142 RGD:1624291
G Sgcb sarcoglycan, beta JBrowse link 14 37,113,194 37,128,623 RGD:1624291
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:1624291
G Sgcg sarcoglycan, gamma JBrowse link 15 41,549,330 41,595,275 RGD:1624291
sarcoglycan complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07025986.2 RGD:13792537
G Sgca sarcoglycan, alpha JBrowse link 10 82,770,905 82,785,142 RGD:1624291
RGD:13792537
G Sgcb sarcoglycan, beta JBrowse link 14 37,113,194 37,128,623 RGD:1624291
G Sgcd sarcoglycan, delta JBrowse link 10 32,062,946 32,471,454 RGD:13792537
RGD:1624291
G Sgce sarcoglycan, epsilon JBrowse link 4 29,726,140 29,769,902 RGD:1600115
RGD:13792537
G Sgcg sarcoglycan, gamma JBrowse link 15 41,549,330 41,595,275 RGD:13792537
RGD:1624291
G Sgcz sarcoglycan zeta JBrowse link 16 57,136,433 58,206,350 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      glycoprotein complex 21
        dystrophin-associated glycoprotein complex 21
          dystroglycan complex 8
            sarcoglycan complex 7
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      membrane 9936
        membrane protein complex 1210
          plasma membrane protein complex 554
            dystrophin-associated glycoprotein complex 21
              dystroglycan complex 8
                sarcoglycan complex 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.