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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin mediated immune response
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Accession:GO:0016064 term browser browse the term
Definition:An immune response mediated by immunoglobulins, whether cell-bound or in solution.
Synonyms:exact_synonym: antibody-mediated immune response


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immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL10 BCL10 immune signaling adaptor JBrowse link 1 86,679,646 86,690,841 RGD:9068941
G CD19 CD19 molecule JBrowse link 16 29,320,734 29,327,860 RGD:9068941
G CD27 CD27 molecule JBrowse link 12 6,492,119 6,499,427 RGD:9068941
G CD74 CD74 molecule JBrowse link 5 151,830,311 151,841,334 RGD:9068941
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 140,539,555 140,543,545 RGD:9068941
G IL13RA2 interleukin 13 receptor subunit alpha 2 JBrowse link X 114,597,088 114,635,253 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G INPP5D inositol polyphosphate-5-phosphatase D JBrowse link 2B 239,201,762 239,350,190 RGD:9068941
G IRF7 interferon regulatory factor 7 JBrowse link 11 647,827 651,314 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 3 38,319,024 38,323,572 RGD:9068941
G PRKCD protein kinase C delta JBrowse link 3 54,330,328 54,357,910 RGD:9068941
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 JBrowse link 11 66,429,435 66,441,327 RGD:9068941
G TLR8 toll like receptor 8 JBrowse link X 12,808,144 12,824,720 RGD:9068941
B cell affinity maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTK Bruton tyrosine kinase JBrowse link X 100,684,017 100,720,868 RGD:9068941
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain JBrowse link 6 33,353,599 33,360,284 RGD:9068941
complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APCS amyloid P component, serum JBrowse link 1 138,734,046 138,735,093 RGD:9068941
G C1QA complement C1q A chain JBrowse link 1 22,770,557 22,773,682 RGD:9068941
G C1QB complement C1q B chain JBrowse link 1 22,787,003 22,795,599 RGD:9068941
G C1QBP complement C1q binding protein JBrowse link 17 5,473,239 5,479,735 RGD:9068941
G C1QC complement C1q C chain JBrowse link 1 22,777,679 22,782,176 RGD:9068941
G C1R complement C1r JBrowse link 12 7,126,723 7,137,895 RGD:9068941
G C1RL complement C1r subcomponent like JBrowse link 12 7,139,831 7,155,259 RGD:9068941
G C1S complement C1s JBrowse link 12 7,107,214 7,117,614 RGD:9068941
G C2 complement C2 JBrowse link 6 32,476,791 32,492,982 RGD:9068941
G C3 complement C3 JBrowse link 19 6,629,240 6,674,786 RGD:9068941
G C4BPA complement component 4 binding protein alpha JBrowse link 1 186,985,220 187,025,898 RGD:9068941
G C4BPB complement component 4 binding protein beta JBrowse link 1 186,969,905 186,981,024 RGD:9068941
G C5 complement C5 JBrowse link 9 120,416,256 120,548,366 RGD:9068941
G C6 complement C6 JBrowse link 5 74,171,926 74,288,590 RGD:9068941
G C7 complement C7 JBrowse link 5 74,447,559 74,520,730 RGD:9068941
G C8A complement C8 alpha chain JBrowse link 1 57,847,726 57,912,392 RGD:9068941
G C8B complement C8 beta chain JBrowse link 1 57,923,720 57,960,674 RGD:9068941
G C8G complement C8 gamma chain JBrowse link 9 136,974,094 136,976,345 RGD:9068941
G C9 complement C9 JBrowse link 5 76,051,911 76,130,725 RGD:9068941
G CD46 CD46 molecule JBrowse link 1 188,138,616 188,182,046 RGD:9068941
G CD55 CD55 molecule (Cromer blood group) JBrowse link 1 187,201,195 187,240,350 RGD:9068941
G CFI complement factor I JBrowse link 4 112,804,645 112,865,581 RGD:9068941
G CLU clusterin JBrowse link 8 24,070,053 24,086,934 RGD:9068941
G CR1 complement C3b/C4b receptor 1 (Knops blood group) JBrowse link 1 187,372,483 187,971,517 RGD:9068941
G CR2 complement C3d receptor 2 JBrowse link 1 187,330,483 187,366,069 RGD:9068941
G CRP C-reactive protein JBrowse link 1 138,858,353 138,860,652 RGD:9068941
G IGLL1 immunoglobulin lambda like polypeptide 1 JBrowse link 22 22,422,600 22,430,386 RGD:9068941
G MASP2 mannan binding lectin serine peptidase 2 JBrowse link 1 11,006,990 11,030,734 RGD:9068941
G MBL2 mannose binding lectin 2 JBrowse link 10 51,537,129 51,543,041 RGD:9068941
G SERPING1 serpin family G member 1 JBrowse link 11 56,309,685 56,326,639 RGD:9068941
G SUSD4 sushi domain containing 4 JBrowse link 1 203,911,484 204,055,677 RGD:9068941
humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL3 BCL3 transcription coactivator JBrowse link 19 50,300,536 50,313,005 RGD:9068941
G CD81 CD81 molecule JBrowse link 11 2,442,322 2,449,308 RGD:9068941
G EXO1 exonuclease 1 JBrowse link 1 222,389,684 222,431,556 RGD:9068941
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain JBrowse link 6 33,353,599 33,360,284 RGD:9068941
immune complex formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TREX1 three prime repair exonuclease 1 JBrowse link 3 49,469,406 49,471,371 RGD:9068941
immunoglobulin biosynthetic process involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TREX1 three prime repair exonuclease 1 JBrowse link 3 49,469,406 49,471,371 RGD:9068941
immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 15 56,886,258 56,894,488 RGD:9068941
immunoglobulin production involved in immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGL2 fibrinogen like 2 JBrowse link 7 82,926,035 82,932,550 RGD:9068941
G GAPT GRB2 binding adaptor protein, transmembrane JBrowse link 5 57,144,459 57,145,229 RGD:9068941
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain JBrowse link 6 33,353,599 33,360,284 RGD:9068941
immunoglobulin secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G POU2F2 POU class 2 homeobox 2 JBrowse link 19 47,568,984 47,656,779 RGD:9068941
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 12 8,903,288 8,913,895 RGD:9068941
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 74,919,115 74,943,652 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 50,951,674 50,994,600 RGD:9068941
G EXO1 exonuclease 1 JBrowse link 1 222,389,684 222,431,556 RGD:9068941
G EXOSC3 exosome component 3 JBrowse link 9 38,552,659 38,558,075 RGD:9068941
G EXOSC6 exosome component 6 JBrowse link 7 152,645,545 152,657,307 RGD:9068941
G LIG4 DNA ligase 4 JBrowse link 13 108,474,718 108,485,421 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 2A 48,824,469 48,849,779 RGD:9068941
G NBN nibrin JBrowse link 8 88,575,198 88,626,200 RGD:9068941
G RNF168 ring finger protein 168 JBrowse link 3 203,755,988 203,791,324 RGD:9068941
G RNF8 ring finger protein 8 JBrowse link 6 38,108,414 38,145,949 RGD:9068941
G SWAP70 switching B cell complex subunit SWAP70 JBrowse link 11 9,526,752 9,614,422 RGD:9068941
G UNG uracil DNA glycosylase JBrowse link 12 110,067,882 110,080,891 RGD:9068941
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCR6 C-C motif chemokine receptor 6 JBrowse link 6 170,069,689 170,084,779 RGD:9068941
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 2B 202,623,497 202,637,045 RGD:9068941
negative regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4BPA complement component 4 binding protein alpha JBrowse link 1 186,985,220 187,025,898 RGD:9068941
G C4BPB complement component 4 binding protein beta JBrowse link 1 186,969,905 186,981,024 RGD:9068941
G CR1 complement C3b/C4b receptor 1 (Knops blood group) JBrowse link 1 187,372,483 187,971,517 RGD:9068941
G SUSD4 sushi domain containing 4 JBrowse link 1 203,911,484 204,055,677 RGD:9068941
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXJ1 forkhead box J1 JBrowse link 17 75,637,615 75,642,571 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
G PTPN6 protein tyrosine phosphatase non-receptor type 6 JBrowse link 12 6,991,099 7,008,830 RGD:9068941
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 53,112,494 53,119,053 RGD:9068941
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 18 17,692,797 17,742,572 RGD:9068941
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
negative regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FCER2 Fc fragment of IgE receptor II JBrowse link 19 7,833,851 7,843,510 RGD:9068941
G HPX hemopexin JBrowse link 11 6,246,392 6,256,410 RGD:9068941
G LTA lymphotoxin alpha JBrowse link 6 32,123,353 32,125,375 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 32,126,618 32,129,389 RGD:9068941
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD226 CD226 molecule JBrowse link 18 66,533,949 66,627,580 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 19 50,399,367 50,443,024 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C17H17orf99 chromosome 17 C17orf99 homolog JBrowse link 17 77,776,151 77,796,139 RGD:9068941
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 9 38,552,659 38,558,075 RGD:9068941
G EXOSC6 exosome component 6 JBrowse link 7 152,645,545 152,657,307 RGD:9068941
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 3 133,694,676 133,721,519 RGD:9068941
G KMT5B lysine methyltransferase 5B JBrowse link 11 66,546,398 66,581,553 RGD:9068941
G KMT5C lysine methyltransferase 5C JBrowse link 19 61,073,185 61,079,389 RGD:9068941
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,654,963 11,671,364 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G RIF1 replication timing regulatory factor 1 JBrowse link 2B 155,985,960 156,109,726 RGD:9068941
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,537,989 5,642,107 RGD:9068941
G SHLD2 shieldin complex subunit 2 JBrowse link 14 87,923,049 87,928,101 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 40,519,012 40,626,845 RGD:9068941
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 4 1,938,777 2,027,425 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNFSF13 TNF superfamily member 13 JBrowse link 17 7,576,518 7,579,834 RGD:9068941
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 66,034,536 66,042,114 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 32,068,645 32,085,099 RGD:9068941
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 209,076,388 209,111,213 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,973,343 9,988,131 RGD:9068941
positive regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTK Bruton tyrosine kinase JBrowse link X 100,684,017 100,720,868 RGD:9068941
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 140,539,555 140,543,545 RGD:9068941
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 19 6,629,240 6,674,786 RGD:9068941
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 140,539,555 140,543,545 RGD:9068941
positive regulation of type III hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BTK Bruton tyrosine kinase JBrowse link X 100,684,017 100,720,868 RGD:9068941
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 140,539,555 140,543,545 RGD:9068941
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 2A 69,632,459 69,744,611 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 17 28,578,199 28,617,347 RGD:9068941
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,323,618 14,343,636 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941

Term paths to the root
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Term Annotations click to browse term
  biological_process 15702
    immune system process 2729
      immune effector process 1106
        leukocyte mediated immunity 739
          lymphocyte mediated immunity 240
            B cell mediated immunity 115
              immunoglobulin mediated immune response 113
                humoral immune response mediated by circulating immunoglobulin + 43
                immune complex formation 1
                immunoglobulin production involved in immunoglobulin mediated immune response + 58
                immunoglobulin-mediated neutralization 0
                negative regulation of immunoglobulin mediated immune response + 12
                positive regulation of immunoglobulin mediated immune response + 37
                regulation of immunoglobulin mediated immune response + 53
                type I hypersensitivity + 3
                type II hypersensitivity + 3
                type III hypersensitivity + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.