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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin mediated immune response
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Accession:GO:0016064 term browser browse the term
Definition:An immune response mediated by immunoglobulins, whether cell-bound or in solution.
Synonyms:exact_synonym: antibody-mediated immune response


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immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10 immune signaling adaptor JBrowse link NW_004955423 8,710,231 8,720,530 RGD:9068941
G Cd19 CD19 molecule JBrowse link NW_004955493 6,540,160 6,544,077 RGD:9068941
G Cd27 CD27 molecule JBrowse link NW_004955413 4,102,740 4,107,739 RGD:9068941
G Cd74 CD74 molecule JBrowse link NW_004955415 4,129,151 4,138,336 RGD:9068941
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link NW_004955468 12,971,931 12,975,206 RGD:9068941
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link NW_004955490 708,144 758,195 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link NW_004955453 2,938,659 3,037,211 RGD:9068941
G Irf7 interferon regulatory factor 7 JBrowse link NW_004955476 11,442,781 11,445,706 RGD:9068941
G Myd88 MYD88 innate immune signal transduction adaptor JBrowse link NW_004955427 25,553,589 25,557,654 RGD:9068941
G Prkcd protein kinase C delta JBrowse link NW_004955430 3,125,066 3,151,857 RGD:9068941
G Tcirg1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 JBrowse link NW_004955422 17,768,469 17,778,976 RGD:9068941
G Tlr8 toll like receptor 8 JBrowse link NW_004955544 302,027 317,110 RGD:9068941
B cell affinity maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link NW_004955503 7,483,819 7,515,085 RGD:9068941
complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apcs amyloid P component, serum JBrowse link NW_004955468 11,388,154 11,389,259 RGD:9068941
G C1qa complement C1q A chain JBrowse link NW_004955452 2,753,362 2,756,220 RGD:9068941
G C1qb complement C1q B chain JBrowse link NW_004955452 2,765,844 2,771,695 RGD:9068941
G C1qbp complement C1q binding protein JBrowse link NW_004955467 10,788,142 10,792,272 RGD:9068941
G C1qc complement C1q C chain JBrowse link NW_004955452 2,759,079 2,762,522 RGD:9068941
G C1r complement C1r JBrowse link NW_004955413 4,652,156 4,660,897 RGD:9068941
G C1rl complement C1r subcomponent like JBrowse link NW_004955413 4,663,643 4,670,454 RGD:9068941
G C1s complement C1s JBrowse link NW_004955413 4,620,450 4,630,860 RGD:9068941
G C2 complement C2 JBrowse link NW_004955437 449,171 460,898 RGD:9068941
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G C4bpa complement component 4 binding protein alpha JBrowse link NW_004955406 42,613,659 42,641,918 RGD:9068941
G C4bpb complement component 4 binding protein beta JBrowse link NW_004955406 42,601,164 42,608,912 RGD:9068941
G C7 complement C7 JBrowse link NW_004955426 25,173,463 25,230,897 RGD:9068941
G C8a complement C8 alpha chain JBrowse link NW_004955464 2,806,859 2,874,444 RGD:9068941
G C8b complement C8 beta chain JBrowse link NW_004955464 2,754,655 2,796,423 RGD:9068941
G C9 complement C9 JBrowse link NW_004955426 23,790,792 23,824,117 RGD:9068941
G Cd46 CD46 molecule JBrowse link NW_004955406 43,002,817 43,034,555 RGD:9068941
G Cd55 CD55 molecule (Cromer blood group) JBrowse link NW_004955406 42,773,368 42,796,205 RGD:9068941
G Cfi complement factor I JBrowse link NW_004955496 492,217 553,398 RGD:9068941
G Clu clusterin JBrowse link NW_004955403 50,160,598 50,175,876 RGD:9068941
G Cr2 complement C3d receptor 2 JBrowse link NW_004955406 42,877,041 42,910,970 RGD:9068941
G Masp2 mannan binding lectin serine peptidase 2 JBrowse link NW_004955486 2,641,730 2,655,125 RGD:9068941
G Mbl2 mannose binding lectin 2 JBrowse link NW_004955425 7,704,371 7,708,951 RGD:9068941
G Serping1 serpin family G member 1 JBrowse link NW_004955511 2,545,337 2,557,850 RGD:9068941
G Susd4 sushi domain containing 4 JBrowse link NW_004955520 1,444,618 1,523,214 RGD:9068941
humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3 transcription coactivator JBrowse link NW_004955555 1,898,280 1,911,466 RGD:9068941
G Cd81 CD81 molecule JBrowse link NW_004955422 14,155,682 14,175,181 RGD:9068941
G Exo1 exonuclease 1 JBrowse link NW_004955406 10,248,981 10,276,207 RGD:9068941
G Zp3 zona pellucida glycoprotein 3 JBrowse link NW_004955456 15,013,472 15,020,809 RGD:9068941
immune complex formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trex1 three prime repair exonuclease 1 JBrowse link NW_004955532 533,877 535,767 RGD:9068941
immunoglobulin biosynthetic process involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trex1 three prime repair exonuclease 1 JBrowse link NW_004955532 533,877 535,767 RGD:9068941
immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link NW_004955450 15,204,502 15,211,747 RGD:9068941
immunoglobulin production involved in immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgl2 fibrinogen like 2 JBrowse link NW_004955410 7,899,263 7,903,499 RGD:9068941
G Gapt GRB2 binding adaptor protein, transmembrane JBrowse link NW_004955446 9,631,970 9,639,215 RGD:9068941
immunoglobulin secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou2f2 POU class 2 homeobox 2 JBrowse link NW_004955555 759,308 793,500 RGD:9068941
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family AAA domain containing 5 JBrowse link NW_004955481 6,986,128 7,031,113 RGD:9068941
G Batf basic leucine zipper ATF-like transcription factor JBrowse link NW_004955523 42,365 66,103 RGD:9068941
G Cd40lg CD40 ligand JBrowse link NW_004955489 8,465,571 8,477,714 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004955555 2,393,510 2,430,180 RGD:9068941
G Exo1 exonuclease 1 JBrowse link NW_004955406 10,248,981 10,276,207 RGD:9068941
G Exosc3 exosome component 3 JBrowse link NW_004955419 28,683,896 28,692,006 RGD:9068941
G Exosc6 exosome component 6 JBrowse link NW_004955484 3,088,133 3,089,551 RGD:9068941
G Lig4 DNA ligase 4 JBrowse link NW_004955404 3,606,077 3,615,193 RGD:9068941
G Mlh1 mutL homolog 1 JBrowse link NW_004955421 3,890,291 3,936,892 RGD:9068941
G Msh2 mutS homolog 2 JBrowse link NW_004955441 14,188,315 14,247,608 RGD:9068941
G Msh6 mutS homolog 6 JBrowse link NW_004955441 14,451,207 14,471,316 RGD:9068941
G Nbn nibrin JBrowse link NW_004955417 6,840,916 6,880,479 RGD:9068941
G Rnf168 ring finger protein 168 JBrowse link NW_004955420 12,656,815 12,676,836 RGD:9068941
G Rnf8 ring finger protein 8 JBrowse link NW_004955437 5,807,592 5,832,213 RGD:9068941
G Swap70 switching B cell complex subunit SWAP70 JBrowse link NW_004955414 25,385,648 25,444,743 RGD:9068941
G Ung uracil DNA glycosylase JBrowse link NW_004955455 10,266,989 10,282,196 RGD:9068941
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr6 C-C motif chemokine receptor 6 JBrowse link NW_004955439 14,921,524 14,949,493 RGD:9068941
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link NW_004955403 3,062,724 3,073,419 RGD:9068941
negative regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein alpha JBrowse link NW_004955406 42,613,659 42,641,918 RGD:9068941
G C4bpb complement component 4 binding protein beta JBrowse link NW_004955406 42,601,164 42,608,912 RGD:9068941
G Susd4 sushi domain containing 4 JBrowse link NW_004955520 1,444,618 1,523,214 RGD:9068941
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
G Foxj1 forkhead box J1 JBrowse link NW_004955506 6,127,551 6,132,302 RGD:9068941
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 JBrowse link NW_004955413 4,525,954 4,547,177 RGD:9068941
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly(ADP-ribose) polymerase family member 3 JBrowse link NW_004955532 3,591,484 3,597,549 RGD:9068941
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Thoc1 THO complex 1 JBrowse link NW_004955402 9,675,211 9,708,045 RGD:9068941
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6 transcription repressor JBrowse link NW_004955420 19,998,960 20,021,200 RGD:9068941
G Foxp3 forkhead box P3 JBrowse link NW_004955543 731,707 742,606 RGD:9068941
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link NW_004955415 11,643,846 11,666,131 RGD:9068941
negative regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link NW_004955462 14,639,396 14,653,801 RGD:9068941
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer2 Fc fragment of IgE receptor II JBrowse link NW_004955563 1,587,471 1,596,707 RGD:9068941
G Hpx hemopexin JBrowse link NW_004955414 22,158,654 22,169,133 RGD:9068941
G Lta lymphotoxin alpha JBrowse link NW_004955437 114,216 116,003 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004955406 35,005,577 35,127,395 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd226 CD226 molecule JBrowse link NW_004955402 53,408,861 53,560,896 RGD:9068941
G Nectin2 nectin cell adhesion molecule 2 JBrowse link NW_004955555 1,959,702 1,985,679 RGD:9068941
G Tnfsf4 TNF superfamily member 4 JBrowse link NW_004955406 13,477,077 13,493,309 RGD:9068941
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102026773 chromosome unknown open reading frame, human C17orf99 JBrowse link NW_004955506 4,397,221 4,408,645 RGD:9068941
G Xcl1 X-C motif chemokine ligand 1 JBrowse link NW_004955462 8,594,416 8,598,101 RGD:9068941
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link NW_004955406 13,477,077 13,493,309 RGD:9068941
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link NW_004955419 28,683,896 28,692,006 RGD:9068941
G Exosc6 exosome component 6 JBrowse link NW_004955484 3,088,133 3,089,551 RGD:9068941
G Hmces 5-hydroxymethylcytosine binding, ES cell specific JBrowse link NW_004955429 13,616,647 13,638,657 RGD:9068941
G Kmt5b lysine methyltransferase 5B JBrowse link NW_004955422 17,626,606 17,684,890 RGD:9068941
G Kmt5c lysine methyltransferase 5C JBrowse link NW_004955567 895,334 901,240 RGD:9068941
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link NW_004955486 2,191,903 2,197,193 RGD:9068941
G Paxip1 PAX interacting protein 1 JBrowse link NW_004955491 8,177,422 8,219,764 RGD:9068941
G Rif1 replication timing regulatory factor 1 JBrowse link NW_004955440 16,977,710 17,047,809 RGD:9068941
G Shld1 shieldin complex subunit 1 JBrowse link NW_004955415 16,180,074 16,282,937 RGD:9068941
G Shld2 shieldin complex subunit 2 JBrowse link NW_004955510 6,021,477 6,114,745 RGD:9068941
G Tfrc transferrin receptor JBrowse link NW_004955420 12,348,392 12,372,714 RGD:9068941
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link NW_004955416 9,962,736 10,035,433 RGD:9068941
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link NW_004955421 3,890,291 3,936,892 RGD:9068941
G Msh2 mutS homolog 2 JBrowse link NW_004955441 14,188,315 14,247,608 RGD:9068941
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link NW_004955514 1,084,522 1,162,624 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin like cytokine factor 1 JBrowse link NW_004955422 18,097,779 18,108,628 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
G Stat6 signal transducer and activator of transcription 6 JBrowse link NW_004955458 4,833,417 4,847,956 RGD:9068941
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family AAA domain containing 5 JBrowse link NW_004955481 6,986,128 7,031,113 RGD:9068941
G Cd28 CD28 molecule JBrowse link NW_004955457 11,159,769 11,253,099 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
G Mlh1 mutL homolog 1 JBrowse link NW_004955421 3,890,291 3,936,892 RGD:9068941
G Msh2 mutS homolog 2 JBrowse link NW_004955441 14,188,315 14,247,608 RGD:9068941
G Paxip1 PAX interacting protein 1 JBrowse link NW_004955491 8,177,422 8,219,764 RGD:9068941
G Ptprc protein tyrosine phosphatase receptor type C JBrowse link NW_004955406 35,005,577 35,127,395 RGD:9068941
G Tbx21 T-box transcription factor 21 JBrowse link NW_004955451 13,315,237 13,317,888 RGD:9068941
positive regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link NW_004955503 7,483,819 7,515,085 RGD:9068941
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link NW_004955468 12,971,931 12,975,206 RGD:9068941
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link NW_004955468 12,971,931 12,975,206 RGD:9068941
positive regulation of type III hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link NW_004955503 7,483,819 7,515,085 RGD:9068941
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link NW_004955468 12,971,931 12,975,206 RGD:9068941
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link NW_004955424 16,338,546 16,449,074 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link NW_004955481 4,462,270 4,497,364 RGD:9068941
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link NW_004955543 731,707 742,606 RGD:9068941
G Il27ra interleukin 27 receptor subunit alpha JBrowse link NW_004955415 32,749,682 32,762,532 RGD:9068941
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link NW_004955415 11,643,846 11,666,131 RGD:9068941
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msh2 mutS homolog 2 JBrowse link NW_004955441 14,188,315 14,247,608 RGD:9068941

Term paths to the root
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Term Annotations click to browse term
  biological_process 14568
    immune system process 2499
      immune effector process 1002
        leukocyte mediated immunity 665
          lymphocyte mediated immunity 212
            B cell mediated immunity 107
              immunoglobulin mediated immune response 106
                humoral immune response mediated by circulating immunoglobulin + 37
                immune complex formation 1
                immunoglobulin production involved in immunoglobulin mediated immune response + 56
                immunoglobulin-mediated neutralization 0
                negative regulation of immunoglobulin mediated immune response + 11
                positive regulation of immunoglobulin mediated immune response + 37
                regulation of immunoglobulin mediated immune response + 52
                type I hypersensitivity + 3
                type II hypersensitivity + 3
                type III hypersensitivity + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.