Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:type I hypersensitivity
go back to main search page
Accession:GO:0016068 term browser browse the term
Definition:An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
Comment:Note that localized and systemic anaphylaxis is usually a result of type I hypersensitivity.
Synonyms:exact_synonym: immediate hypersensitivity response
 xref: Wikipedia:Type_I_hypersensitivity


show annotations for term's descendants       view all columns           Sort by:
 
negative regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
positive regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:11040701
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    immune system process 2631
      immune response 1575
        inflammatory response to antigenic stimulus 83
          acute inflammatory response to antigenic stimulus 34
            hypersensitivity 16
              type I hypersensitivity 6
                negative regulation of type I hypersensitivity 1
                positive regulation of type I hypersensitivity 5
                regulation of type I hypersensitivity + 6
                type I hypersensitivity mediated by basophils 0
                type I hypersensitivity mediated by mast cells 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    response to stimulus 10457
      response to stress 3959
        defense response 1551
          inflammatory response 706
            inflammatory response to antigenic stimulus 83
              acute inflammatory response to antigenic stimulus 34
                hypersensitivity 16
                  type I hypersensitivity 6
                    negative regulation of type I hypersensitivity 1
                    positive regulation of type I hypersensitivity 5
                    regulation of type I hypersensitivity + 6
                    type I hypersensitivity mediated by basophils 0
                    type I hypersensitivity mediated by mast cells 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.