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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic vesicle docking
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Accession:GO:0016081 term browser browse the term
Definition:The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
Comment:Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).
Synonyms:exact_synonym: synaptic vesicle docking involved in exocytosis
 related_synonym: synaptic vesicle docking during exocytosis


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synaptic vesicle docking term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctbp2 C-terminal binding protein 2 JBrowse link 1 205,001,354 205,030,565 RGD:1624291
G Ppfia3 PTPRF interacting protein alpha 3 JBrowse link 1 101,328,547 101,357,391 RGD:1600115
RGD:1624291
G Rims1 regulating synaptic membrane exocytosis 1 JBrowse link 9 28,440,408 28,973,246 RGD:1624291
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:1624291
G Sptbn2 spectrin, beta, non-erythrocytic 2 JBrowse link 1 219,964,429 220,006,811 RGD:70020
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:8553325
G Stx1b syntaxin 1B JBrowse link 1 199,251,842 199,270,465 RGD:1600115
RGD:1624291
G Stx3 syntaxin 3 JBrowse link 1 228,137,781 228,195,004 RGD:68313
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:68313
G Syde1 synapse defective Rho GTPase homolog 1 JBrowse link 7 14,037,646 14,043,632 RGD:1624291
G Unc13a unc-13 homolog A JBrowse link 16 20,056,398 20,103,951 RGD:1624291
RGD:13792537
RGD:1600115
G Unc13b unc-13 homolog B JBrowse link 5 58,505,449 58,714,396 RGD:1624291
RGD:13792537
G Unc13c unc-13 homolog C JBrowse link 8 80,202,736 80,656,363 RGD:13792537
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
regulation of synaptic vesicle docking term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:1600115
RGD:1624291
G Septin5 septin 5 JBrowse link 11 86,516,377 86,522,169 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      exocytic process 99
        vesicle docking involved in exocytosis 49
          synaptic vesicle docking 16
            regulation of synaptic vesicle docking 2
            synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    localization 6430
      establishment of localization 4940
        transport 4800
          export from cell 1233
            secretion by cell 1184
              signal release 863
                signal release from synapse 209
                  neurotransmitter secretion 209
                    synaptic vesicle exocytosis 157
                      synaptic vesicle docking 16
                        regulation of synaptic vesicle docking 2
                        synaptic vesicle tethering involved in synaptic vesicle exocytosis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.