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Term:urocanate hydratase activity
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Accession:GO:0016153 term browser browse the term
Definition:Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O.
Synonyms:related_synonym: 3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming);   3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity;   imidazolonepropionate hydrolase activity;   urocanase activity
 xref: EC:;   KEGG_REACTION:R02914;   MetaCyc:UROCANATE-HYDRATASE-RXN;   RHEA:13101;   reactome:R-HSA-70903 "urocanate + H2O => 4-imidazolone-5-propionate"

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urocanate hydratase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uroc1 urocanate hydratase 1 ISO
RGD PMID:19304569, PMID:21873635 RGD:13792537 NCBI chr 4:122,244,744...122,276,357
Ensembl chr 4:122,244,711...122,276,361
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  molecular_function 20471
    catalytic activity 6068
      lyase activity 212
        carbon-oxygen lyase activity 92
          hydro-lyase activity 71
            urocanate hydratase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.