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Term:prefoldin complex
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Accession:GO:0016272 term browser browse the term
Definition:A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
Synonyms:narrow_synonym: GIM complex
 xref: Wikipedia:Prefoldin

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prefoldin complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pfdn1 prefoldin subunit 1 JBrowse link 18 29,233,987 29,290,447 RGD:1600115
G Pfdn2 prefoldin subunit 2 JBrowse link 13 89,725,113 89,743,849 RGD:1600115
G Pfdn4 prefoldin subunit 4 JBrowse link 3 168,124,634 168,132,739 RGD:13792537
G Pfdn5 prefoldin subunit 5 JBrowse link 7 143,924,662 143,929,400 RGD:13792537
G Pfdn6 prefoldin subunit 6 JBrowse link 20 5,455,974 5,457,448 RGD:1624291
G Vbp1 VHL binding protein 1 JBrowse link 1 148,425,046 148,443,505 RGD:13792537

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  cellular_component 19809
    protein-containing complex 5770
      prefoldin complex 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.