Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:somatic cell DNA recombination
go back to main search page
Accession:GO:0016444 term browser browse the term
Definition:Recombination occurring within or between DNA molecules in somatic cells.


show annotations for term's descendants       view all columns           Sort by:
 
somatic cell DNA recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Swap70 switching B-cell complex subunit SWAP70 JBrowse link 1 174,862,683 174,924,101 RGD:1624291
immunoglobulin heavy chain V-D-J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polb DNA polymerase beta JBrowse link 16 74,237,001 74,260,272 RGD:1624291
immunoglobulin V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
RGD:13792537
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
RGD:13792537
G Tcf3 transcription factor 3 JBrowse link 7 12,146,642 12,168,400 RGD:1624291
RGD:13792537
RGD:1600115
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
RGD:13792537
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:1600115
RGD:1624291
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1624291
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
RGD:1600115
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1600115
RGD:1624291
G Rnf168 ring finger protein 168 JBrowse link 11 71,721,242 71,743,421 RGD:1624291
RGD:1600115
G Rnf8 ring finger protein 8 JBrowse link 20 8,285,380 8,309,858 RGD:1624291
RGD:1600115
G Swap70 switching B-cell complex subunit SWAP70 JBrowse link 1 174,862,683 174,924,101 RGD:1624291
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
G Hmces 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 4 119,841,088 119,864,115 RGD:1600115
RGD:1624291
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:1600115
RGD:1624291
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1600115
RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 14 82,119,210 82,196,501 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
RGD:13792537
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin-like cytokine factor 1 JBrowse link 1 219,468,866 219,472,445 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:13792537
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1624291
G Mir181b1 microRNA 181b-1 JBrowse link 13 54,952,903 54,953,012 RGD:1624291
G Mir181b2 microRNA 181b-2 JBrowse link 3 23,151,455 23,151,542 RGD:1624291
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 10 65,470,470 65,507,581 RGD:1624291
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
somatic recombination of immunoglobulin gene segments term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:1624291
RGD:13792537
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
RGD:13792537
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:13792537
T cell receptor V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1624291
RGD:1600115
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Tcf7 transcription factor 7 JBrowse link 10 37,616,033 37,646,027 RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1600115
V(D)J recombination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291
G Dcaf1 DDB1 and CUL4 associated factor 1 JBrowse link 8 115,538,365 115,615,282 RGD:1624291
G Dclre1c DNA cross-link repair 1C JBrowse link 17 78,782,512 78,812,140 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Lig1 DNA ligase 1 JBrowse link 1 75,356,212 75,394,757 RGD:1624291
G Lig3 DNA ligase 3 JBrowse link 10 70,134,734 70,158,051 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
RGD:13792537
G Rag2 recombination activating 2 JBrowse link 3 91,191,837 91,200,134 RGD:1624291
RGD:13792537
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      cellular metabolic process 10737
        cellular macromolecule metabolic process 8223
          DNA metabolic process 887
            DNA recombination 309
              somatic cell DNA recombination 74
                somatic diversification of immune receptors via gene conversion + 0
                somatic diversification of immune receptors via germline recombination within a single locus + 74
Path 2
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      cellular metabolic process 10737
        cellular nitrogen compound metabolic process 6385
          nucleobase-containing compound metabolic process 5276
            nucleic acid metabolic process 4782
              DNA metabolic process 887
                DNA recombination 309
                  somatic cell DNA recombination 74
                    somatic diversification of immune receptors via gene conversion + 0
                    somatic diversification of immune receptors via germline recombination within a single locus + 74
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.