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ONTOLOGY REPORT - ANNOTATIONS


Term:somatic hypermutation of immunoglobulin genes
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Accession:GO:0016446 term browser browse the term
Definition:Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.
Synonyms:exact_synonym: somatic hypermutation of antibody genes


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somatic hypermutation of immunoglobulin genes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1624291
G Mcm3ap minichromosome maintenance complex component 3 associated protein JBrowse link 20 12,879,304 12,917,069 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:13792537
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:1600115
G Msh3 mutS homolog 3 JBrowse link 2 21,790,048 21,931,791 RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
RGD:13792537
G Nuggc nuclear GTPase, germinal center associated JBrowse link 15 49,011,951 49,055,246 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
RGD:13792537
G Polb DNA polymerase beta JBrowse link 16 74,237,001 74,260,272 RGD:1624291
G Polm DNA polymerase mu JBrowse link 14 86,069,378 86,079,327 RGD:1624291
G Polq DNA polymerase theta JBrowse link 11 66,585,860 66,695,369 RGD:1624291
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 JBrowse link 3 153,210,829 153,250,705 RGD:1624291
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    immune system process 2641
      somatic diversification of immune receptors 80
        somatic diversification of immune receptors via somatic mutation 15
          somatic hypermutation of immunoglobulin genes 14
            somatic hypermutation of immunoglobulin genes involved in immune response 0
Path 2
Term Annotations click to browse term
  biological_process 19334
    developmental process 6638
      anatomical structure development 6107
        multicellular organism development 5579
          system development 5100
            immune system development 1031
              somatic diversification of immune receptors 80
                somatic diversification of immune receptors via somatic mutation 15
                  somatic hypermutation of immunoglobulin genes 14
                    somatic hypermutation of immunoglobulin genes involved in immune response 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.