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ONTOLOGY REPORT - ANNOTATIONS


Term:protein processing
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Accession:GO:0016485 term browser browse the term
Definition:Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Synonyms:exact_synonym: protein maturation by peptide bond cleavage;   protein maturation by peptide bond hydrolysis
 related_synonym: peptidolysis during protein maturation;   protein maturation by proteolysis
 alt_id: GO:0051605
 xref: MIPS_funcat:14.07.11;   MIPS_funcat:18.01.05


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protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:1624291
RGD:1600115
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 JBrowse link 10 36,098,051 36,304,416 RGD:1624291
RGD:1600115
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 JBrowse link 14 19,866,278 20,072,896 RGD:1624291
RGD:1600115
G Aebp1 AE binding protein 1 JBrowse link 14 86,101,253 86,111,323 RGD:13792537
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 63,141,418 63,185,510 RGD:1624291
G Aph1a aph-1 homolog A, gamma secretase subunit JBrowse link 2 198,006,247 198,009,837 RGD:1624291
RGD:13792537
G Aph1b aph-1 homolog B, gamma secretase subunit JBrowse link 8 72,508,008 72,598,921 RGD:1624291
RGD:13792537
G Asprv1 aspartic peptidase, retroviral-like 1 JBrowse link 4 118,431,755 118,433,286 RGD:1624291
G C2cd3 C2 domain containing 3 centriole elongation regulator JBrowse link 1 165,382,279 165,480,088 RGD:1624291
RGD:1600115
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:1624291
RGD:1600115
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:1624291
RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
RGD:1600115
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:1624291
RGD:1600115
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
RGD:1600115
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Cpd carboxypeptidase D JBrowse link 10 63,325,764 63,389,811 RGD:13792537
G Cpe carboxypeptidase E JBrowse link 16 26,906,716 27,014,811 RGD:1626225
RGD:13792537
G Cpm carboxypeptidase M JBrowse link 7 60,654,350 60,714,620 RGD:13792537
G Cpn1 carboxypeptidase N subunit 1 JBrowse link 1 263,733,887 263,762,758 RGD:13792537
G Cpxm1 carboxypeptidase X (M14 family), member 1 JBrowse link 3 122,913,886 122,920,684 RGD:13792537
G Cpxm2 carboxypeptidase X (M14 family), member 2 JBrowse link 1 204,048,785 204,161,090 RGD:13792537
G Cpz carboxypeptidase Z JBrowse link 14 80,402,946 80,426,203 RGD:13792537
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:1624291
RGD:1600115
G Ddi2 DNA damage inducible 1 homolog 2 JBrowse link 5 160,230,958 160,282,836 RGD:1624291
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 JBrowse link 8 5,217,054 5,436,969 RGD:1600115
RGD:1624291
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:728596
RGD:1624291
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:1624291
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:1624291
RGD:1600115
G Fkrp fukutin related protein JBrowse link 1 78,733,461 78,740,803 RGD:1624291
RGD:1600115
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:633598
RGD:13792537
RGD:1624291
RGD:1582619
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Ift172 intraflagellar transport 172 JBrowse link 6 26,390,686 26,485,459 RGD:1624291
G Klk13 kallikrein related-peptidase 13 JBrowse link 1 99,648,658 99,661,025 RGD:1624291
RGD:1600115
G LOC108348064 gamma-secretase subunit APH-1B-like JBrowse link 8 72,608,217 72,629,257 RGD:13792537
G Lonp2 lon peptidase 2, peroxisomal JBrowse link 19 21,400,736 21,492,634 RGD:1624291
RGD:13792537
G Metap2 methionyl aminopeptidase 2 JBrowse link 7 34,762,241 34,789,456 RGD:1624291
RGD:1600115
G Mmp16 matrix metallopeptidase 16 JBrowse link 5 31,568,344 31,818,368 RGD:1600115
RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
G Ncstn nicastrin JBrowse link 13 90,451,046 90,467,256 RGD:724403
RGD:13792537
RGD:1600115
RGD:1624291
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase JBrowse link X 71,540,870 71,585,906 RGD:1600115
RGD:1624291
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:1624291
RGD:13792537
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:1624291
RGD:13792537
G Pcsk4 proprotein convertase subtilisin/kexin type 4 JBrowse link 7 12,247,498 12,255,721 RGD:1600115
RGD:13792537
RGD:1624291
G Pcsk5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 236,031,988 236,313,858 RGD:1624291
RGD:13792537
G Pcsk6 proprotein convertase subtilisin/kexin type 6 JBrowse link 1 126,749,508 126,947,392 RGD:1624291
RGD:13792537
G Pcsk7 proprotein convertase subtilisin/kexin type 7 JBrowse link 8 50,200,069 50,222,655 RGD:1624291
RGD:13792537
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1582518
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 JBrowse link 18 22,964,121 23,047,896 RGD:628447
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1358417
RGD:1624291
RGD:1600115
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
RGD:1600115
G Psenen presenilin enhancer gamma secretase subunit JBrowse link 1 89,016,093 89,017,449 RGD:1624291
RGD:1600115
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
RGD:1600115
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
G Rnpep arginyl aminopeptidase JBrowse link 13 52,092,863 52,124,006 RGD:2325944
G Sde2 SDE2 telomere maintenance homolog JBrowse link 13 99,136,921 99,153,187 RGD:1600115
RGD:1624291
G Srgn serglycin JBrowse link 20 32,120,317 32,158,071 RGD:1624291
RGD:1600115
G Tysnd1 trypsin domain containing 1 JBrowse link 20 31,313,018 31,318,736 RGD:1624291
RGD:13792537
RGD:1600115
G Xpnpep3 X-prolyl aminopeptidase 3 JBrowse link 7 122,636,252 122,686,983 RGD:1624291
RGD:1600115
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:1624291
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asph aspartate-beta-hydroxylase JBrowse link 5 22,577,680 22,799,333 RGD:1624291
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:13792537
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
RGD:1600115
G Cideb cell death-inducing DFFA-like effector b JBrowse link 15 34,439,844 34,444,244 RGD:1624291
RGD:1600115
G Cyfip2 cytoplasmic FMR1 interacting protein 2 JBrowse link 10 31,278,746 31,419,235 RGD:1624291
RGD:13792537
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Lgmn legumain JBrowse link 6 126,282,246 126,308,207 RGD:1600115
RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835366
G Perp PERP, TP53 apoptosis effector JBrowse link 1 14,224,392 14,236,838 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
RGD:1600115
G Tbc1d10a TBC1 domain family, member 10a JBrowse link 14 84,417,320 84,445,034 RGD:1624291
RGD:1600115
activation of plasma proteins involved in acute inflammatory response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:1624291
RGD:1600115
angiotensin maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp6ap2 ATPase H+ transporting accessory protein 2 JBrowse link X 11,137,889 11,164,854 RGD:1624291
RGD:1600115
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:5132599
RGD:13792537
RGD:1624291
CAAX-box protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like JBrowse link 1 169,720,247 169,721,788 RGD:1624291
G Rce1 Ras converting CAAX endopeptidase 1 JBrowse link 1 219,860,826 219,863,933 RGD:1600115
RGD:13792537
RGD:1624291
G Zmpste24 zinc metallopeptidase STE24 JBrowse link 5 139,982,404 140,015,541 RGD:13792537
dibasic protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1600115
RGD:1624291
endothelin maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:1624291
RGD:1600115
enkephalin processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpe carboxypeptidase E JBrowse link 16 26,906,716 27,014,811 RGD:6483103
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:1624291
RGD:1600115
Factor XII activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
RGD:1600115
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:11062094
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:1624291
RGD:1600115
RGD:13792537
G Cst7 cystatin F JBrowse link 3 146,363,913 146,373,365 RGD:1600115
RGD:1624291
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:10047164
RGD:10047212
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Fcmr Fc fragment of IgM receptor JBrowse link 13 47,602,701 47,617,065 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
RGD:1600115
insulin processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpe carboxypeptidase E JBrowse link 16 26,906,716 27,014,811 RGD:1626225
RGD:1600115
RGD:1624291
G Ero1b endoplasmic reticulum oxidoreductase 1 beta JBrowse link 17 90,709,394 90,783,110 RGD:1624291
RGD:1600115
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:1624291
RGD:1600115
intein-mediated protein splicing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhh desert hedgehog signaling molecule JBrowse link 7 140,575,288 140,580,783 RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1600115
islet amyloid polypeptide processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:8554260
mitochondrial protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afg3l1 AFG3(ATPase family gene 3)-like 1 (S. cerevisiae) JBrowse link 19 56,272,171 56,299,323 RGD:13792537
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 63,141,418 63,185,510 RGD:1624291
RGD:13792537
G Atp23 ATP23 metallopeptidase and ATP synthase assembly factor homolog JBrowse link 7 70,183,625 70,198,655 RGD:13792537
G LOC100910779 ATP-dependent zinc metalloprotease YME1L1-like JBrowse link 17 89,701,899 89,741,953 RGD:1624291
G Oma1 OMA1 zinc metallopeptidase JBrowse link 5 122,847,624 122,900,475 RGD:1624291
RGD:1600115
G Stoml2 stomatin like 2 JBrowse link 5 58,472,561 58,476,158 RGD:1624291
RGD:1600115
G Yme1l1 YME1-like 1 ATPase JBrowse link 17 89,701,899 89,741,919 RGD:1624291
RGD:1600115
negative regulation of plasminogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cpb2 carboxypeptidase B2 JBrowse link 15 57,290,849 57,339,762 RGD:7243115
G Ctsz cathepsin Z JBrowse link 3 172,527,107 172,537,877 RGD:1624291
RGD:1600115
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:1624291
RGD:1600115
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:1624291
RGD:1600115
G Serpinf2 serpin family F member 2 JBrowse link 10 62,264,247 62,272,353 RGD:1624291
RGD:1600115
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
RGD:1600115
negative regulation of protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp4 acid phosphatase 4 JBrowse link 1 100,226,311 100,234,536 RGD:1600115
RGD:1624291
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:1624291
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 JBrowse link 3 111,160,205 111,163,425 RGD:1624291
RGD:1600115
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:11566024
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:1624291
RGD:1600115
G Glg1 golgi glycoprotein 1 JBrowse link 19 42,983,879 43,088,074 RGD:1624291
RGD:1600115
G Il1r2 interleukin 1 receptor type 2 JBrowse link 9 46,840,646 46,881,241 RGD:1624291
RGD:1600115
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like JBrowse link 1 169,720,247 169,721,788 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
RGD:1600115
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317364
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:9999170
G Snx12 sorting nexin 12 JBrowse link X 70,989,822 71,127,330 RGD:1624291
RGD:1600115
G Tmem59 transmembrane protein 59 JBrowse link 5 126,783,061 126,804,177 RGD:1624291
RGD:1600115
G Tmem98 transmembrane protein 98 JBrowse link 10 68,173,380 68,184,289 RGD:1600115
RGD:1624291
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt4 sirtuin 4 JBrowse link 12 46,862,358 46,876,593 RGD:9586053
neuropeptide processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mme membrane metallo-endopeptidase JBrowse link 2 153,799,203 153,880,910 RGD:1600115
RGD:1624291
peptide hormone processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Corin corin, serine peptidase JBrowse link 14 38,247,379 38,474,931 RGD:1600115
RGD:1624291
G Cpe carboxypeptidase E JBrowse link 16 26,906,716 27,014,811 RGD:727682
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:1624291
G Ece2 endothelin-converting enzyme 2 JBrowse link 11 83,948,896 83,985,429 RGD:1303943
RGD:1624291
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:13792537
RGD:1600115
G LOC103690091 proSAAS JBrowse link X 15,324,261 15,328,617 RGD:1624291
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:1601276
RGD:13792537
RGD:1624291
RGD:2308913
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:1601276
RGD:1624291
RGD:1600115
G Pcsk4 proprotein convertase subtilisin/kexin type 4 JBrowse link 7 12,247,498 12,255,721 RGD:13792537
G Pcsk5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 236,031,988 236,313,858 RGD:1624291
RGD:13792537
G Pcsk6 proprotein convertase subtilisin/kexin type 6 JBrowse link 1 126,749,508 126,947,392 RGD:729476
RGD:13792537
RGD:1600115
RGD:1624291
G Scg5 secretogranin V JBrowse link 3 105,235,065 105,279,475 RGD:1600115
RGD:1624291
plasminogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoh apolipoprotein H JBrowse link 10 96,640,013 96,653,939 RGD:1624291
RGD:1600115
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:1624291
RGD:1600115
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:1624291
RGD:1600115
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:1624291
RGD:1600115
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:1624291
RGD:1600115
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:1624291
RGD:1600115
G H2bc1 H2B clustered histone 1 JBrowse link 17 43,423,111 43,423,580 RGD:1624291
RGD:1600115
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:1624291
RGD:1600115
G LOC100910418 tissue-type plasminogen activator-like JBrowse link 16 73,745,767 73,763,198 RGD:1600115
G Pgk1 phosphoglycerate kinase 1 JBrowse link X 77,263,399 77,279,373 RGD:1624291
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:11537479
RGD:13792537
RGD:1624291
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:1600115
RGD:13792537
RGD:1624291
G Tmprss9 transmembrane serine protease 9 JBrowse link 7 11,678,591 11,710,581 RGD:1624291
positive regulation of plasminogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec3b C-type lectin domain family 3, member B JBrowse link 8 132,241,016 132,248,066 RGD:1624291
RGD:1600115
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:1624291
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
RGD:1600115
G Hpn hepsin JBrowse link 1 89,534,112 89,549,575 RGD:1600115
RGD:1624291
G Meltf melanotransferrin JBrowse link 11 72,135,311 72,158,106 RGD:1624291
RGD:1600115
G Plgrkt plasminogen receptor with a C-terminal lysine JBrowse link 1 247,502,274 247,514,540 RGD:1624291
RGD:13792537
G Ruvbl1 RuvB-like AAA ATPase 1 JBrowse link 4 120,411,917 120,447,458 RGD:67924
positive regulation of protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angptl8 angiopoietin-like 8 JBrowse link 8 22,855,495 22,858,565 RGD:1624291
RGD:1600115
G Astl astacin like metalloendopeptidase JBrowse link 3 119,783,717 119,799,450 RGD:1624291
RGD:1600115
G Bag2 Bcl2-associated athanogene 2 JBrowse link 9 38,456,487 38,467,120 RGD:1624291
RGD:1600115
G Ccbe1 collagen and calcium binding EGF domains 1 JBrowse link 18 61,758,754 62,013,194 RGD:1624291
G Cntn2 contactin 2 JBrowse link 13 49,280,913 49,314,061 RGD:1624291
RGD:1600115
G Ctnnd1 catenin delta 1 JBrowse link 3 72,001,904 72,053,047 RGD:1624291
G Fuz fuzzy planar cell polarity protein JBrowse link 1 100,891,832 100,896,811 RGD:1624291
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:7242176
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1582606
G Nkd2 NKD inhibitor of WNT signaling pathway 2 JBrowse link 1 32,054,390 32,085,416 RGD:1624291
RGD:1600115
G Rhbdd1 rhomboid domain containing 1 JBrowse link 9 88,110,731 88,229,462 RGD:1624291
RGD:1600115
G Spon1 spondin 1 JBrowse link 1 178,568,777 178,935,715 RGD:1624291
RGD:1600115
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Timm17a translocase of inner mitochondrial membrane 17A JBrowse link 13 52,124,641 52,136,127 RGD:13463485
G Timm23 translocase of inner mitochondrial membrane 23 JBrowse link 16 8,324,038 8,350,067 RGD:13463485
G Tnp1 transition protein 1 JBrowse link 9 80,294,837 80,295,446 RGD:1624291
RGD:1600115
G Tnp2 transition protein 2 JBrowse link 10 4,953,898 4,954,626 RGD:1600115
RGD:1624291
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:1624291
RGD:1600115
G Myh9 myosin, heavy chain 9 JBrowse link 7 118,740,005 118,792,507 RGD:1624291
protein autoprocessing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 JBrowse link 18 63,141,418 63,185,510 RGD:1624291
RGD:1600115
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:1626249
RGD:2303057
G Capn2 calpain 2 JBrowse link 13 100,878,649 100,928,811 RGD:1626249
RGD:2303057
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:1624291
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:2311459
G Ctse cathepsin E JBrowse link 13 48,426,833 48,449,493 RGD:2325171
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:1624291
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
RGD:1600115
G Fxn frataxin JBrowse link 1 242,123,975 242,152,834 RGD:1624291
RGD:1600115
G Hjv hemojuvelin BMP co-receptor JBrowse link 2 198,655,437 198,659,318 RGD:1624291
RGD:1600115
G Myrf myelin regulatory factor JBrowse link 1 226,260,558 226,292,650 RGD:1600115
RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1601081
G Pcsk1 proprotein convertase subtilisin/kexin type 1 JBrowse link 2 91,450,162 91,497,091 RGD:2308914
G Pcsk2 proprotein convertase subtilisin/kexin type 2 JBrowse link 3 137,618,891 137,923,385 RGD:1624291
RGD:1600115
G Pcsk9 proprotein convertase subtilisin/kexin type 9 JBrowse link 5 126,031,368 126,053,726 RGD:1582518
RGD:1624291
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pisd phosphatidylserine decarboxylase JBrowse link 14 83,298,630 83,347,697 RGD:1600115
G Tmprss2 transmembrane serine protease 2 JBrowse link 11 38,063,914 38,103,406 RGD:1624291
RGD:13792537
protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Immp1l inner mitochondrial membrane peptidase subunit 1 JBrowse link 3 95,955,126 96,024,316 RGD:13792537
G Immp2l inner mitochondrial membrane peptidase subunit 2 JBrowse link 6 60,958,351 61,859,457 RGD:1624291
G Mipep mitochondrial intermediate peptidase JBrowse link 15 41,084,180 41,192,621 RGD:13792537
G Pmpca peptidase, mitochondrial processing alpha subunit JBrowse link 3 3,834,262 3,842,061 RGD:1600115
RGD:1624291
RGD:13792537
G Pmpcb peptidase, mitochondrial processing beta subunit JBrowse link 4 9,908,838 9,921,615 RGD:13463464
RGD:14995326
RGD:1624291
RGD:13792537
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 JBrowse link 1 190,555,177 190,585,741 RGD:13792537
regulation of plasminogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:13792537
G Anxa9 annexin A9 JBrowse link 2 196,470,318 196,481,568 RGD:13792537
regulation of protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ift52 intraflagellar transport 52 JBrowse link 3 159,388,868 159,413,358 RGD:1624291
RGD:1600115
G Ift88 intraflagellar transport 88 JBrowse link 15 37,690,417 37,786,855 RGD:1624291
G Inpp5b inositol polyphosphate-5-phosphatase B JBrowse link 5 142,731,767 142,796,305 RGD:1624291
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 JBrowse link 3 91,596,730 91,839,054 RGD:1624291
RGD:1600115
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:1624291
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1624291
RGD:1600115
G Prkacb protein kinase cAMP-activated catalytic subunit beta JBrowse link 2 252,602,197 252,691,886 RGD:1624291
RGD:1600115
G Prss37 serine protease 37 JBrowse link 4 68,337,498 68,349,286 RGD:1624291
RGD:1600115
G Rfx4 regulatory factor X4 JBrowse link 7 25,831,358 25,909,976 RGD:1624291
RGD:1600115
G Rnf139 ring finger protein 139 JBrowse link 7 98,770,840 98,782,025 RGD:1624291
RGD:1600115
G Rps6ka2 ribosomal protein S6 kinase A2 JBrowse link 1 53,219,346 53,499,445 RGD:1624291
RGD:1600115
signal peptide processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arxes2 adipocyte-related X-chromosome expressed sequence 2 JBrowse link X 106,522,900 106,524,832 RGD:13792537
G Cln5 CLN5, intracellular trafficking protein JBrowse link 15 93,634,815 93,644,146 RGD:1624291
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291
RGD:1600115
G Hm13 histocompatibility minor 13 JBrowse link 3 148,150,695 148,189,623 RGD:13792537
G MGC109340 similar to Microsomal signal peptidase 23 kDa subunit (SPase 22 kDa subunit) (SPC22/23) JBrowse link X 106,487,872 106,489,391 RGD:13792537
G Pcsk5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 236,031,988 236,313,858 RGD:1624291
G Sec11a SEC11 homolog A, signal peptidase complex subunit JBrowse link 1 142,733,423 142,759,999 RGD:1600115
RGD:13792537
G Sec11c SEC11 homolog C, signal peptidase complex subunit JBrowse link 18 61,490,051 61,506,393 RGD:1600115
RGD:13792537
G Spcs1 signal peptidase complex subunit 1 JBrowse link 16 7,080,389 7,081,957 RGD:13792537
G Spcs2 signal peptidase complex subunit 2 JBrowse link 1 164,829,896 164,849,749 RGD:13792537
G Spcs3 signal peptidase complex subunit 3 JBrowse link 16 40,050,862 40,056,296 RGD:13792537
G Sppl3 signal peptide peptidase like 3 JBrowse link 12 47,276,485 47,360,552 RGD:13792537
trypsinogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cuzd1 CUB and zona pellucida-like domains 1 JBrowse link 1 201,881,846 201,894,970 RGD:1624291
RGD:1600115
vacuolar protein processing term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgmn legumain JBrowse link 6 126,282,246 126,308,207 RGD:13792537
G Tmem208 transmembrane protein 208 JBrowse link 19 37,282,018 37,284,718 RGD:13792537
zymogen activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07003241.2 RGD:13792537
G AABR07003244.1 RGD:13792537
G C1r complement C1r JBrowse link 4 157,126,060 157,136,825 RGD:1624291
RGD:13792537
G C1rl complement C1r subcomponent like JBrowse link 4 157,108,190 157,122,689 RGD:13792537
G Cd5l Cd5 molecule-like JBrowse link 2 186,685,104 186,696,117 RGD:13792537
G Ctsh cathepsin H JBrowse link 8 97,439,155 97,458,293 RGD:1600115
RGD:1624291
G Dcbld1 discoidin, CUB and LCCL domain containing 1 JBrowse link 20 33,359,062 33,455,161 RGD:13792537
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1600115
RGD:1624291
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:1624291
RGD:13792537
RGD:1600115
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1600115
RGD:1624291
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:1624291
RGD:1600115
G Klk1 kallikrein 1 JBrowse link 1 100,131,562 100,135,556 RGD:13792537
G Klk1b3 kallikrein 1-related peptidase B3 JBrowse link 1 100,199,057 100,203,260 RGD:13792537
G Klk1c10 kallikrein 1-related peptidase C10 JBrowse link 1 99,890,294 99,894,353 RGD:13792537
G Klk1c12 kallikrein 1-related peptidase C12 JBrowse link 1 99,298,965 99,303,048 RGD:13792537
G Klk1c2 kallikrein 1-related peptidase C2 JBrowse link 1 99,981,045 99,985,422 RGD:13792537
G Klk1c3 kallikrein 1-related peptidase C3 JBrowse link 1 100,141,205 100,163,945 RGD:13792537
G Klk1c6 kallikrein 1-related peptidase C6 JBrowse link 1 99,947,714 99,964,824 RGD:13792537
G Klk1c8 kallikrein 1-related peptidase C8 JBrowse link 1 99,352,114 99,355,976 RGD:13792537
G Klk1c9 kallikrein 1-related peptidase C9 JBrowse link 1 100,086,520 100,090,406 RGD:13792537
G LOC100911689 glandular kallikrein-10-like JBrowse link 1 99,323,893 99,327,978 RGD:13792537
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:1624291
RGD:13792537
G Prss12 serine protease 12 JBrowse link 2 227,657,983 227,717,884 RGD:1624291
RGD:13792537
G Prss3 serine protease 3 JBrowse link 4 70,614,524 70,617,998 RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
zymogen inhibition term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Furin furin (paired basic amino acid cleaving enzyme) JBrowse link 1 142,185,092 142,198,167 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    metabolic process 11438
      primary metabolic process 10300
        protein metabolic process 5943
          proteolysis 1817
            protein processing 228
              CAAX-box protein processing 3
              Notch receptor processing, ligand-independent 0
              activation of plasma proteins involved in acute inflammatory response + 3
              dibasic protein processing + 1
              mitochondrial protein processing + 14
              negative regulation of protein processing + 32
              neuropeptide processing 1
              peptide bond cleavage involved in epidermal growth factor receptor ligand maturation 0
              peptide hormone processing + 15
              positive regulation of protein processing + 27
              protein autoprocessing 18
              protein initiator methionine removal involved in protein maturation 0
              protein processing in phagocytic vesicle + 2
              protein splicing + 3
              regulation of protein processing + 72
              signal peptide processing + 12
              sterol regulatory element binding protein cleavage + 0
              vacuolar protein processing 2
              zymogen activation + 66
Path 2
Term Annotations click to browse term
  biological_process 19245
    metabolic process 11438
      organic substance metabolic process 10836
        macromolecule metabolic process 9317
          protein metabolic process 5943
            proteolysis 1817
              protein processing 228
                CAAX-box protein processing 3
                Notch receptor processing, ligand-independent 0
                activation of plasma proteins involved in acute inflammatory response + 3
                dibasic protein processing + 1
                mitochondrial protein processing + 14
                negative regulation of protein processing + 32
                neuropeptide processing 1
                peptide bond cleavage involved in epidermal growth factor receptor ligand maturation 0
                peptide hormone processing + 15
                positive regulation of protein processing + 27
                protein autoprocessing 18
                protein initiator methionine removal involved in protein maturation 0
                protein processing in phagocytic vesicle + 2
                protein splicing + 3
                regulation of protein processing + 72
                signal peptide processing + 12
                sterol regulatory element binding protein cleavage + 0
                vacuolar protein processing 2
                zymogen activation + 66
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.