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ONTOLOGY REPORT - ANNOTATIONS


Term:histone deacetylation
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Accession:GO:0016575 term browser browse the term
Definition:The modification of histones by removal of acetyl groups.


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histone deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baz2a bromodomain adjacent to zinc finger domain, 2A JBrowse link 7 2,518,267 2,548,840 RGD:1624291
G Brms1 BRMS1, transcriptional repressor and anoikis regulator JBrowse link 1 220,325,352 220,334,616 RGD:13792537
G Brms1l BRMS1 like transcriptional repressor JBrowse link 6
6
76,675,399
76,743,243
76,708,261
76,753,950
RGD:13792537
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
G Hdac10 histone deacetylase 10 JBrowse link 7 130,102,335 130,109,036 RGD:1624291
G Hdac11 histone deacetylase 11 JBrowse link 4 122,781,095 122,798,355 RGD:1624291
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1600115
RGD:1624291
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:1304416
RGD:1624291
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:1624291
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
G Hopx HOP homeobox JBrowse link 14 33,354,803 33,362,547 RGD:1624291
G LOC108348098 breast cancer metastasis-suppressor 1 homolog JBrowse link 1 220,418,455 220,427,785 RGD:13792537
G Mier1 MIER1 transcriptional regulator JBrowse link 5 122,642,065 122,693,642 RGD:1624291
RGD:13792537
G Mier2 MIER family member 2 JBrowse link 7 13,039,759 13,055,632 RGD:1624291
RGD:13792537
G Mier3 MIER family member 3 JBrowse link 2 43,266,301 43,295,175 RGD:1624291
G Morf4l1 mortality factor 4 like 1 JBrowse link 8 97,473,454 97,494,974 RGD:1624291
RGD:13792537
RGD:1600115
G Morf4l2 mortality factor 4 like 2 JBrowse link X 107,394,468 107,405,564 RGD:13792537
G Msl3 MSL complex subunit 3 JBrowse link X 27,015,826 27,033,562 RGD:13792537
G Msl3l2 male-specific lethal 3-like 2 (Drosophila) JBrowse link 20 37,580,002 37,590,015 RGD:13792537
G Mta1 metastasis associated 1 JBrowse link 6 137,911,302 137,950,066 RGD:13792537
G Mta2 metastasis associated 1 family, member 2 JBrowse link 1 225,140,863 225,149,584 RGD:13792537
G Mta3 metastasis associated 1 family, member 3 JBrowse link 6 6,904,449 7,036,929 RGD:13792537
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:1624291
G Prdm5 PR/SET domain 5 JBrowse link 4 96,659,062 96,810,816 RGD:1624291
G Rbm14 RNA binding motif protein 14 JBrowse link 1 220,048,740 220,067,124 RGD:1624291
G Sin3a SIN3 transcription regulator family member A JBrowse link 8 61,748,590 61,803,314 RGD:13792537
G Sin3b SIN3 transcription regulator family member B JBrowse link 16 18,842,456 18,860,086 RGD:13792537
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:1624291
G Suds3 SDS3 homolog, SIN3A corepressor complex component JBrowse link 12 45,199,012 45,221,507 RGD:1624291
RGD:13792537
G Tbl1x transducin (beta)-like 1 X-linked JBrowse link X 44,959,883 44,988,551 RGD:13792537
G Tbl1xr1 TBL1X receptor 1 JBrowse link 2 107,221,913 107,359,229 RGD:13792537
histone H3 deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:5688291
G Elk4 ETS transcription factor ELK4 JBrowse link 13 48,788,262 48,813,267 RGD:1624291
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:2316171
RGD:13792537
RGD:1624291
G Hdac1l histone deacetylase 1-like JBrowse link 9 84,893,145 84,894,599 RGD:13792537
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590255
RGD:13792537
RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:5688291
RGD:13792537
RGD:1600115
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:1600115
G Hdac7 histone deacetylase 7 JBrowse link 7 139,280,396 139,319,108 RGD:1600115
G Hdac8 histone deacetylase 8 JBrowse link X 72,163,777 72,370,058 RGD:13792537
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
G Per1 period circadian regulator 1 JBrowse link 10 55,681,761 55,696,557 RGD:1600115
RGD:1624291
G Per2 period circadian regulator 2 JBrowse link 9 98,555,154 98,597,362 RGD:1624291
RGD:1600115
G Sfpq splicing factor proline and glutamine rich JBrowse link 5 145,079,803 145,088,517 RGD:1624291
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:2316169
RGD:13792537
RGD:1624291
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:1600115
RGD:1624291
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:1600115
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:13792537
G Sirt7 sirtuin 7 JBrowse link 10 109,796,046 109,802,821 RGD:1600115
RGD:1624291
RGD:13792537
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` JBrowse link 4 95,884,020 95,945,248 RGD:1624291
RGD:1600115
histone H3-K9 deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1600115
G Sirt6 sirtuin 6 JBrowse link 7 10,937,622 10,943,048 RGD:1600115
histone H4 deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Baz2a bromodomain adjacent to zinc finger domain, 2A JBrowse link 7 2,518,267 2,548,840 RGD:1624291
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:1624291
RGD:13792537
RGD:1600115
G Hdac1l histone deacetylase 1-like JBrowse link 9 84,893,145 84,894,599 RGD:13792537
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:1624291
RGD:13792537
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1624291
RGD:13792537
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:1624291
G Hdac8 histone deacetylase 8 JBrowse link X 72,163,777 72,370,058 RGD:13792537
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
G Rcor1 REST corepressor 1 JBrowse link 6 135,475,470 135,552,155 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1600115
RGD:1624291
G Sirt2 sirtuin 2 JBrowse link 1 86,948,866 86,971,954 RGD:1600115
RGD:1624291
G Sirt7 sirtuin 7 JBrowse link 10 109,796,046 109,802,821 RGD:1600115
G Smarcad1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1` JBrowse link 4 95,884,020 95,945,248 RGD:1624291
RGD:1600115
histone H4-K12 deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1624291
histone H4-K16 deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hdac9 histone deacetylase 9 JBrowse link 6 53,487,367 54,358,694 RGD:1624291
negative regulation of histone deacetylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdm5a lysine demethylase 5A JBrowse link 4 152,892,388 152,972,196 RGD:1624291
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
negative regulation of histone deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like JBrowse link 1 169,720,247 169,721,788 RGD:1624291
G Prmt6 protein arginine methyltransferase 6 JBrowse link 2 213,173,403 213,180,721 RGD:1624291
G Ski SKI proto-oncogene JBrowse link 5 172,556,196 172,623,878 RGD:1600115
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1600115
positive regulation of histone deacetylase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Prkd1 protein kinase D1 JBrowse link 6 71,035,017 71,349,531 RGD:1624291
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
G RGD735065 similar to GI:13385412-like protein splice form I JBrowse link 20 6,869,870 6,910,022 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
positive regulation of histone deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap8 A-kinase anchoring protein 8 JBrowse link 7 14,323,298 14,339,953 RGD:1624291
G Akap8l A-kinase anchoring protein 8 like JBrowse link 7 14,340,168 14,369,835 RGD:1624291
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Ctbp1 C-terminal binding protein 1 JBrowse link 14 82,762,109 82,789,350 RGD:1624291
RGD:1600115
G Ing2 inhibitor of growth family, member 2 JBrowse link 16 47,714,756 47,725,836 RGD:1624291
G Jdp2 Jun dimerization protein 2 JBrowse link 6 109,464,910 109,505,591 RGD:1624291
G Lpin1 lipin 1 JBrowse link 6 41,796,214 41,905,149 RGD:1624291
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:1624291
G Nipbl NIPBL, cohesin loading factor JBrowse link 2 57,508,830 57,676,197 RGD:1624291
G Pml PML nuclear body scaffold JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 JBrowse link 5 16,904,926 16,930,111 RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
regulation of histone deacetylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:1600115
G Tada2a transcriptional adaptor 2A JBrowse link 10 71,393,701 71,441,435 RGD:1624291
G Tada3 transcriptional adaptor 3 JBrowse link 4 145,318,417 145,330,291 RGD:1624291
G Znhit1 zinc finger, HIT-type containing 1 JBrowse link 12 22,726,643 22,732,917 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      cellular component organization or biogenesis 6706
        cellular component organization 6456
          chromatin organization 834
            covalent chromatin modification 507
              histone modification 492
                histone deacetylation 80
                  histone H3 deacetylation + 20
                  histone H4 deacetylation + 13
                  histone deacetylation at centromere + 0
                  negative regulation of histone deacetylation + 7
                  positive regulation of histone deacetylation + 21
                  regulation of histone deacetylation + 32
Path 2
Term Annotations click to browse term
  biological_process 19858
    metabolic process 12096
      organic substance metabolic process 11494
        macromolecule metabolic process 9943
          macromolecule modification 4106
            protein modification process 3901
              cellular protein modification process 3901
                protein deacylation 114
                  protein deacetylation 102
                    histone deacetylation 80
                      histone H3 deacetylation + 20
                      histone H4 deacetylation + 13
                      histone deacetylation at centromere + 0
                      negative regulation of histone deacetylation + 7
                      positive regulation of histone deacetylation + 21
                      regulation of histone deacetylation + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.