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ONTOLOGY REPORT - ANNOTATIONS


Term:lipoate-protein ligase activity
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Accession:GO:0016979 term browser browse the term
Definition:Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP.
Synonyms:narrow_synonym: lipoate-protein ligase A activity;   lipoate-protein ligase B activity;   lipoate-protein ligase activity (lipoylation of glycine cleavage complex)
 alt_id: GO:0008916;   GO:0016978;   GO:0102315
 xref: MetaCyc:RXN-13039;   MetaCyc:RXN-8654;   MetaCyc:RXN-8655;   MetaCyc:RXN0-1141


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lipoate-protein ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipt1 lipoyltransferase 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:44,466,627...44,471,986
Ensembl chr 9:44,466,627...44,471,986
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      catalytic activity, acting on a protein 2312
        lipoate-protein ligase activity 1
Path 2
Term Annotations click to browse term
  molecular_function 20467
    catalytic activity 6067
      transferase activity 2353
        transferase activity, transferring phosphorus-containing groups 956
          nucleotidyltransferase activity 126
            lipoate-protein ligase activity 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.